Jason D. Christie, MD, MSCE
Associate Professor of Medicine
Department: Medicine
Graduate Group Affiliations
Contact information
Division of Pulmonary and Critical Care Medicine
Hospital of the University of Pennsylvania
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania School of Medicine
423 Guardian Drive
719 Blockley Hall
Philadelphia, PA 19104
Hospital of the University of Pennsylvania
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania School of Medicine
423 Guardian Drive
719 Blockley Hall
Philadelphia, PA 19104
Office: (215) 573-3209
Fax: (215) 573-0198
Fax: (215) 573-0198
Email:
jchristi@mail.med.upenn.edu
jchristi@mail.med.upenn.edu
Publications
Links
Search PubMed for articles
Institute for Translational Medicine and Therapeutics
Center for Clinical Epidemiology and Biostatistics faculty webpage
Search PubMed for articles
Institute for Translational Medicine and Therapeutics
Center for Clinical Epidemiology and Biostatistics faculty webpage
Education:
Sc.B. (Chemistry)
Brown University, 1989.
M.D. (Medicine)
Columbia University, 1993.
M.S.C.E. (Clinical Epidemiology)
University of Pennsylvania, 2002.
Permanent linkSc.B. (Chemistry)
Brown University, 1989.
M.D. (Medicine)
Columbia University, 1993.
M.S.C.E. (Clinical Epidemiology)
University of Pennsylvania, 2002.
Description of Research Expertise
Dr. Christie's translational research studies involve the role of oxidative stress, coagulation/fibrinolysis and inflammatory pathways in acute lung injury following lung transplantation (termed primary graft dysfunction); somatic genetic variation; gene expression; and protein biomarkers in the etiology and pathogenesis of acute lung injury in the transplant, sepsis, and trauma populations.Selected Publications
Mikkelsen Mark E, Christie Jason D, Abella Benjamin S, Kerlin Meeta Prasad, Fuchs Barry D, Schweickert William D, Berg Robert A, Mosesso Vincent N, Shofer Frances S, Gaieski David F: Use of Therapeutic Hypothermia After In-Hospital Cardiac Arrest* Critical care medicine 41(6): 1385-1395, Jun 2013.Cantu E, Lederer D J, Meyer K, Milewski K, Suzuki Y, Shah R J, Diamond J M, Meyer N J, Tobias J W, Baldwin D A, Van Deerlin V M, Olthoff K M, Shaked A, Christie J D: Gene Set Enrichment Analysis Identifies Key Innate Immune Pathways in Primary Graft Dysfunction After Lung Transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons May 2013.
Karnatovskaia Lioudmila V, Lee Augustine S, Gajic Ognjen, Festic Emir: The Influence of Prehospital Systemic Corticosteroid Use on Development of Acute Respiratory Distress Syndrome and Hospital Outcomes. Critical care medicine May 2013.
Thabut Gabriel, Christie Jason D, Mal Herve, Fournier Michel, Brugiere Olivier, Leseche Guy, Castier Yves, Rizopoulos Dimitris: Survival Benefit of Lung Transplant for Cystic Fibrosis since Lung-Allocation-Score Implementation. American journal of respiratory and critical care medicine Apr 2013.
Shah R J, Bellamy S L, Lee J C, Cantu E, Diamond J M, Mangalmurti N, Kawut S M, Ware L B, Christie J D: Early plasma soluble receptor for advanced glycation end-product levels are associated with bronchiolitis obliterans syndrome. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 13(3): 754-9, Mar 2013.
Diamond Joshua M, Lee James C, Kawut Steven M, Shah Rupal J, Localio A Russell, Bellamy Scarlett L, Lederer David J, Cantu Edward, Kohl Benjamin A, Lama Vibha N, Bhorade Sangeeta M, Crespo Maria, Demissie Ejigayehu, Sonett Joshua, Wille Keith, Orens Jonathan, Shah Ashish S, Weinacker Ann, Arcasoy Selim, Shah Pali D, Wilkes David S, Ware Lorraine B, Palmer Scott M, Christie Jason D: Clinical risk factors for primary graft dysfunction after lung transplantation. American journal of respiratory and critical care medicine 187(5): 527-34, Mar 2013.
Shah R J, Diamond J M, Cantu E, Lee J C, Lederer D J, Lama V N, Orens J, Weinacker A, Wilkes D S, Bhorade S, Wille K M, Ware L B, Palmer S M, Crespo M, Localio A R, Demissie E J, Kawut S M, Bellamy S L, Christie J D: Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation. Chest Feb 2013.
Meyer NJ, Feng R, Li M, Zhao Y, Sheu CC, Tejera P, Gallop R, Bellamy S, Rushefski M, Lanken PN, Aplenc R, O'Keefe GE, Wurfel MM, Christiani DC, Christie JD: IL1RN Coding Variant Is Associated with Lower Risk of Acute Respiratory Distress Syndrome and Increased Plasma IL1RA. Am J Respir Crit Care Med Page: Epup ahead of print, 2013.
Shah RJ, Diamond JM, Lederer DJ, Arcasoy SM, Cantu E, Demissie EJ, Kawut SM, Kohl B, Lee JC, Sonett J, Christie JD, Ware LB: Plasma Monocyte Chemotactic Protein-1 (MCP-1) levels at 24 hours are a biomarker of primary graft dysfunction following lung transplantation. Transl Research 160(6): 435-42, Dec 2012.
Diamond JM, Porteous MK, Cantu E, Meyer NJ, Shah RJ, Lederer DJ, Kawut SM, Lee J, Bellamy SL, Palmer SM, Lama VN, Bhorade SM, Crespo M, Demissie E, Wille K, Orens J, Shah PD, Weinacker A, Weill D, Arcasoy S, Wilkes DS, Ware LB, Christie JD; Lung Transplant Outcomes Group: Elevated plasma angiopoietin-2 levels and primary graft dysfunction after lung transplantation. PLoS One 7(12): e51932, Dec 2012.