Ulf H Beier, MD

faculty photo
Assistant Professor of Pediatrics
Department: Pediatrics
Graduate Group Affiliations

Contact information
Abramson Research Center, Room 916-C
3615 Civic Center Boulevard
Philadelphia, PA 19104
Office: (215) 590 2449
Fax: (215) 590 7385
Lab: (267) 426 5407
Education:
Dr. med.
Christian Albrechts University of Kiel, Germany, 2004.
MD
Christian Albrechts University of Kiel, Germany, 2004.
Permanent link
 

Selected Publications

Beier, UH, Angelin A, Akimova T, Wang L, Liu Y, Xiao H, Koike MA, Hancock SA, Bhatti TR, Han R, Jiao J, Veasey SC, Sims CA, Baur JA, Wallace DC, Hancock WW: Essential role of mitochondrial energy metabolism in Foxp3+ T-regulatory cell function and allograft survival. FASEB J 29(6): 2315-26, Jun 2015.

Wang L, Liu Y, Han R, Beier UH, Bhatti TR, Akimova T, Greene MI, Hiebert SW, Hancock WW: Foxp3+ regulatory T-cell development and function require histone/protein deacetylase 3. J Clin Invest 125(3): 1111-23, Mar 2015.

Liu Y, Wang L, Han R, Beier UH, Akimova T, Bhatti T, Xiao H, Cole PA, Brindle PK, Hancock WW: Two histone/protein acetyltransferases, CBP and p300, are indispensible for Foxp3+ T-regulatory cell development and function. Mol Cell Biol 34(21): 3993-4007, Nov 2014.

Akimova T, Xiao H, Liu Y, Bhatti T R, Jiao J, Eruslanov E, Singhal S, Wang L, Han R, Zacharia K, Hancock W W, Beier U H: Targeting sirtuin-1 alleviates experimental autoimmune colitis by induction of Foxp3(+) T-regulatory cells. Mucosal immunology 7(5): 1209-20, Sept 2014.

Liu Y, Wang L, Han R, Beier U, Dent S, Hancock W: PCAF promotes TGF-β-induced Foxp3+ regulatory T cell production. Journal of Immunology 192(Supplement no. 1), May 2014.

Akimova T, Xiao H, Jiao J, Bhatti T, Liu Y, Wang L, Hancock W: Targeting sirtuin-1 alleviates experimental autoimmune colitis by induction of Foxp3+ T-regulatory cells. Journal of Immunology 192(Supplement no. 1), May 2014.

Beier UH, Wang Z, Xiao H, Bhatti T, Hancock W, Levine M: Targeting sirtuin-1 improves murine renal allograft survival and function. Journal of Immunology 192(Supplement no. 1), May 2014.

Wang Liqing, Liu Yujie, Han Rongxiang, Beier Ulf H, Thomas Rajan M, Wells Andrew D, Hancock Wayne W: Mbd2 promotes foxp3 demethylation and T-regulatory-cell function. Molecular and Cellular Biology 33(20): 4106-15, Oct 2013.

Liu Y, Wang L, Predina J, Han R, Beier UH, Wang LC, Kapoor V, Bhatti TR, Akimova T, Singhal S, Brindle PK, Cole PA, Albelda SM, Hancock WW: Inhibition of p300 impairs Foxp3⁺ T regulatory cell function and promotes antitumor immunity. Nature Medicine 19(9): 1173-7, Sep 2013.

Wang L, Liu Y, Beier UH, Han R, Bhatti TR, Akimova T, Hancock WW.: Foxp3+ T-regulatory cells require DNA methyltransferase 1 expression to prevent development of lethal autoimmunity. Blood 121(18): 3631-9, May 2013.

back to top
Last updated: 07/20/2015
The Trustees of the University of Pennsylvania