Ulf H Beier, MD

faculty photo
Assistant Professor of Pediatrics
Department: Pediatrics
Graduate Group Affiliations

Contact information
Abramson Research Center, Room 916-C
3615 Civic Center Boulevard
Philadelphia, PA 19104
Office: (215) 590 2449
Lab: (267) 426 5407
Christian Albrechts University of Kiel, Germany, 2004.
Dr. med.
Christian Albrechts University of Kiel, Germany, 2004.
Permanent link

Description of Research Expertise

T cell metabolism
Transplant Immunology
Regulatory T cells

Selected Publications

Ulf H Beier, William J Quinn, Jing Jiao, Tara TeSlaa, Jason Stadanlick, Wayne W Hancock, Evgeniy B Eruslanov, Joshua D Rabinowitz, Joseph A Baur: Nicotinamide adenine dinucleotide (NAD) oxidation preserves T cell function under lactic acidosis characteristic of the tumor microenvironment (TME). The Journal of Immunology 200(1 Supplement): 177.4-177.4, May 2018.

Ulf H Beier, William J Quinn, Jing Jiao, Tara TeSlaa, Satinder Dahiya, Zhonglin Wang, Matthew H Levine, Wayne W Hancock, Joshua D Rabinowitz, Joseph A Baur: Immunosuppression reverse engineered from cancer: Reducing nicotinamide adenine dinucleotide (NAD) impairs effector T cell function through glycolysis. The Journal of Immunology 200(1 Supplement): 55.27-55.27, May 2018.

Tatiana Akimova, Tianyi Zhang, Ulf H Beier, Jing Jiao, Joshua M Diamond, Jason D Christie, Rebecca A Simmons, Wayne W Hancock: Obesity-driven IL-18 inhibits the suppressive function of FOXP3+ T-regulatory (Treg) cells. The Journal of Immunology 200(1 Supplement): 66.52-166.52, May 2018.

Dahiya S, Wang L, Beier UH, Han R, Hancock WW.: HDAC10 Targeting Regulates Foxp3 Promoter, Enhances T-regulatory (Treg) Function and Suppresses Autoimmune Colitis. The Journal of Immunology 200(1 Supplement), May 2018.

Wang L, Beier UH, Akimova T, Dahiya S, Han R, Samanta A, Levine MH, Hancock WW: Histone/protein deacetylase inhibitor therapy for enhancement of Foxp3+ T-regulatory cell function posttransplantation. Am J Transplant March 2018.

Negorev D, Beier UH, Zhang T, Quatromoni JG, Bhojnagarwala P, Albelda SM, Singhal S, Eruslanov E, Lohoff FW, Levine MH, Diamond JM, Christie JD, Hancock WW, Akimova T: Human neutrophils can mimic myeloid-derived suppressor cells (PMN-MDSC) and suppress microbead or lectin-induced T cell proliferation through artefactual mechanisms. Scientific Reports 8(1): 3135, Feb 2018.

Beier UH: Apoptotic Regulatory T Cells Retain Suppressive Function through Adenosine. Cell Metabolism 27(1): 5-7, Jan 2018.

Laskin B, Seif A, Bunin N, Wang Y, Beier U, Altrich M, Jodele S, Daives S, Denburg M: BK viremia is common in children after allogeneic hematopoietic cell transplant. Biol Blood Marrow Transplant 24(3): S87, 2018.

Huang J, Wang L, Dahiya S, Beier UH, Han R, Samanta A, Bergman J, Sotomayor EM, Seto E, Kozikowski AP, Hancock WW: Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function. Scientific reports 7(1): 8626, Aug 2017.

Akimova T, Zhang T, Negorev D, Singhal S, Stadanlick J, Rao A, Annunziata M, Levine MH, Beier UH, Diamond JM, Christie JD, Albelda SM, Eruslanov EB, Hancock WW: Human lung tumor FOXP3+ Tregs upregulate four "Treg-locking" transcription factors. JCI insight 2(16), Aug 2017.

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Last updated: 06/28/2018
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