Ulf H Beier, MD
Assistant Professor of Pediatrics
Department: Pediatrics
Graduate Group Affiliations
Contact information
Abramson Research Center, Room 916-C
3615 Civic Center Boulevard
Philadelphia, PA 19104
3615 Civic Center Boulevard
Philadelphia, PA 19104
Office: (215) 590 2449
Fax: (215) 590 7385
Lab: (267) 426 5407
Fax: (215) 590 7385
Lab: (267) 426 5407
Email:
beieru@email.chop.edu
beieru@email.chop.edu
Publications
Education:
MD
Christian Albrechts University of Kiel, Germany, 2004.
Dr. med.
Christian Albrechts University of Kiel, Germany, 2004.
Permanent linkMD
Christian Albrechts University of Kiel, Germany, 2004.
Dr. med.
Christian Albrechts University of Kiel, Germany, 2004.
Selected Publications
Wang L, Liu Y, Beier UH, Han R, Bhatti TR, Akimova T, Hancock WW.: Foxp3+ T-regulatory cells require DNA methyltransferase 1 expression to prevent development of lethal autoimmunity. Blood 121(18): 3631-9, May 2013.Beier Ulf H, Wang Liqing, Hancock Wayne W: Combination of isoform-selective histone/protein deacetylase inhibitors improves Foxp3+ T-regulatory cell function. Cell cycle 11(18), Aug 2012.
Beier Ulf H, Wang Liqing, Han Rongxiang, Akimova Tatiana, Liu Yujie, Hancock Wayne W: Histone deacetylases 6 and 9 and sirtuin-1 control Foxp3+ regulatory T cell function through shared and isoform-specific mechanisms. Science signaling 5(229): ra45, Jun 2012.
Hancock Wayne W, Akimova Tatiana, Beier Ulf H, Liu Yujie, Wang Liqing: HDAC inhibitor therapy in autoimmunity and transplantation. Annals of the rheumatic diseases 71 Suppl 2: i46-54, Apr 2012.
Akimova Tatiana, Beier Ulf H, Liu Yujie, Wang Liqing, Hancock Wayne W: Histone/protein deacetylases and T-cell immune responses. Blood 119(11): 2443-51, Mar 2012.
Liu Yujie, Wang Liqing, Han Rongxiang, Beier Ulf H, Hancock Wayne W: Two lysines in the forkhead domain of foxp3 are key to T regulatory cell function. PloS one 7(1): e29035, 2012.
Beier Ulf H, Akimova Tatiana, Liu Yujie, Wang Liqing, Hancock Wayne W: Histone/protein deacetylases control Foxp3 expression and the heat shock response of T-regulatory cells. Current opinion in immunology 23(5): 670-8, Oct 2011.
de Zoeten Edwin F, Wang Liqing, Butler Kyle, Beier Ulf H, Akimova Tatiana, Sai Hong, Bradner James E, Mazitschek Ralph, Kozikowski Alan P, Matthias Patrick, Hancock Wayne W: Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells. Molecular and cellular biology 31(10): 2066-78, May 2011.
Beier Ulf H, Wang Liqing, Bhatti Tricia R, Liu Yujie, Han Rongxiang, Ge Guanghui, Hancock Wayne W: Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival. Molecular and cellular biology 31(5): 1022-9, Mar 2011.
Akimova Tatiana, Beier Ulf H, Wang Liqing, Levine Matthew H, Hancock Wayne W: Helios expression is a marker of T cell activation and proliferation. PloS one 6(8): e24226, 2011.