Immunology Graduate Group
Recognizing the need to create an environment where researchers could be adequately trained in the multifaceted aspects of immunobiology, Penn became the first medical school to establish a separate degree-granting PhD program in Immunology. The faculty of the Immunology Graduate Group (IGG) are drawn from eight different units of the University of Pennsylvania, encompassing a broad spectrum of research interests: the College of Arts and Sciences; the School of Medicine; the Hospital of the University of Pennsylvania; The Children's Hospital of Philadelphia; the School of Dental Medicine; the School of Veterinary Medicine; The Wistar Institute; and The Abramson Family Cancer Research Institute.
The IGG has also established a partnership with the National Institutes of Health in Bethesda, MD. The partnership brings to the IGG the extraordinary resources and scientific expertise present at the NIH, one of the largest and most renowned biomedical research centers in the world. Students have the opportunity to interact with NIH faculty in a variety of ways, including conducting a lab rotation or thesis work at the NIH. This cross-departmental and institutional organization fosters a unique collaborative environment that allows students to develop research projects combining the expertise of multiple faculty members.
At present, there are approximately 80 faculty members in Penn’s Immunology Graduate Group, encompassing a broad spectrum of research studies. Faculty research includes studies on the development and regulation of the immune system, host-pathogen interactions, the fundamental molecular and cellular biology of the immune system, structural studies of immunologically relevant molecules and translational immunology. Research results are being utilized in both experimental models and clinical trials attempting to fight diseases.
CAR T-Cell Therapy Success Featured in New York Times and Philly.com
Frederic Bushman and Co-authors Develop New Gene Therapy for "Bubble Boy" Disease
Carolina Lopez and Gudrun Debes and Trainees Awarded AAI Careers in immunology Fellowship
IGG Faculty Receive Penn Medicine Awards of Excellence
David Weiner Developed Technology Being Used to Develop Ebola Vaccine
Rotating cover images: (1) The parasite Leishmania major (promastigote stage; red) among alternatively activated (M2) macrophages (green) and resident peritoneal macrophages (blue). Courtesy of Tiffany Weinkopff and Phillip Scott, Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine. Cropped from original. (2) Goenka R, Matthews AH, Zhang B, O’Neill PJ, Scholz JL, Migone T, Leonard WJ, Stohl W, Hershberg U, Cancro MP. 2014. Local BLyS production by T follicular cells mediates retention of high affinity B cells during affinity maturation. The Journal of Experimental Medicine 211(1):45-56. Cropped from original. (3) Spleen of a mouse infected the chronic strain of LCMV (clone 13). Intravascular labeling was used to differentiate CD8+ T cells in the red pulp versus the white pulp of the spleen. Photo credit: Kristen Pauken and Jason Schenkel. Cropped from original. (4) Tiled 3D reconstruction of an E10.5 dorsal aorta immunostained for CD31 (red) CKit (blue) and Runx1 (green). Amanda Phillips and Nancy Speck.