Jorge Henao-Mejia, M.D., Ph.D.

faculty photo
Assistant Professor of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine
Graduate Group Affiliations

Contact information
The University of Pennsylvania
The Institute for Immunology
Biomedical Research Building II/III, Room 321
Philadelphia, PA 19104
Lab: 215-898-2212
M.D. (Medicine)
University of Antioquia, Colombia, 2005.
Ph.D. (Microbiology and Immunology)
Indiana University, 2009.
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Selected Publications

Wlodarska M., R. Nowarski, C.A. Thaiss, J. Henao-Mejia, J.P. Zhang, G. Frankel, L. Hao, W.M. Philbrick, E. Elinav, B.B. Finlay, R.A. Flavell: NLRP6 inflammasome regulates the intestinal host-microbial interface by orchestrating globlet cell-mediated mucus secretion. Cell 156(5): 1045-1059, 2014.

Henao-Mejia J.*, E. Elinav*, C.A. Thaiss*, R.A. Flavell: Inflammasomes and metabolic disease. Annu Rev Physiol 2014.

Hacisuleyman E., L.A. Goff, C. Trapnell, M. Sauvageau, D.G. Hendrickson, D.R Kelley, P. McClanahan, A. Williams, J. Henao-Mejia, L. Sun, J. Engreitz, M. Guttman, E.S. Lander, R.A. Flavell, H.F. Lodish, A. Raj, J.L. Rinn: Trans-chromosomal and nuclear matrix interactions require a lincRNA that escapes X chromosome inactivation. Nat Struct Mol Biol. 21: 198-206, 2014.

Henao-Mejia, J.*, T. Strowig* and R. Flavell: Microbiota keeps the intestinal clock ticking. Cell 153: 741-743 2013.

Licona-Limon P., J. Henao-Mejia, A.U. Temann, N. Gagliani, I. Licona-Limon, H. Ishigame, L. Hao, D.R. Herbert, R.A. Flavell. : Th9 cells drive host immunity against gastrointestinal worm infection. Immunity 39(4): 744-757, 2013.

Williams A.*, J. Henao-Mejia*, C.D. Harman, R.A. Flavell: miR-181 and metabolic regulation in the immune system. Cold Spring Harb Symp Quant Biol. 78: 223-230, 2013 Notes: *These authors contributed equally to this work.

Henao-Mejia J.*, E. Elinav*, C.A. Thaiss*, R.A. Flavell: The Intestinal microbiota in chronic liver disease. Advances in Immunology 117: 73-97, 2013.

Henao-Mejia J.*, A. Williams*, L.A. Goff, M. Staron, P. Licona-Limón, S.M. Kaech, M. Nakayama, J.L. Rinn, R.A. Flavell: The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis Immunity 38: 1-14, 2013 Notes: *These authors contributed equally to this work.

Henao-Mejia, J.*, E. Elinav*, C.A Thaiss, Paula Licona-Limon, R.A. Flavell: Role of the intestinal microbiome in liver disease. J Autoimmun 46: 66-73, 2013.

Henao-Mejia, J.*, E. Elinav* and R.A. Flavell: Integrative inflammasome activity in the regulation of intestinal mucosal immune responses. Mucosal Immunology 6: 4-13, 2013.

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Last updated: 10/09/2014
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