Perelman School of Medicine at the University of Pennsylvania

McKay Orthopaedic Research Laboratory

Faculty

Louis J. Soslowsky

faculty photo
Fairhill Professor
Department: Orthopaedic Surgery

Contact information
McKay Orthopaedic Research Laboratory
G13A Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104-6081
Office: 215-898-8653
Fax: 215-573-2133
Education:
Diploma
East Brunswick High School , 1982.
B.S. (Engineering Mechanics)
Columbia University, 1986.
M.S. (Engineering Mechanics)
Columbia University, 1987.
M.Phil
Columbia University, 1989.
Ph.D. (Engineering Mech./Biomechanics, Mentor: Van C. Mow)
Columbia University, 1991.
Cert. (Academic Medicine Leadership Program)
Wharton School of the University of Pennsylvania , 2008.
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Description of Research Expertise

orthopaedic research, orthopaedic biomechanics and tissue engineering, tendons and ligaments, shoulder and elbow

Selected Publications

Beach ZM, Tucker JJ, Thomas SJ, Reuther KE, Gray CF, Lee CS, Glaser DL, Soslowsky LJ: Biceps tenotomy in the presence of a supraspinatus tear alters the adjacent intact tendons and glenoid cartilage. J Biomech 63: 151-7, 2017.

Barnum CE, Fey JL, Weiss SN, Barila G, Brown AG, Connizzo BK, Shetye SS, Elovitz MA, Soslowsky LJ: Tensile Mechanical Properties and Dynamic Collagen Fiber Re-Alignment of the Murine Cervix are Dramatically Altered Throughout Pregnancy. J Biomechan Eng 139(6), 2017.

Tucker JJ, Gordon JA, Zanes RC, Zuskov A, Vinciguerra JD, Bloebaum RD, Soslowsky LJ: P(2) porous titanium implants improve tendon healing in an acute rat supraspinatus repair model. J Shoulder Elbow Surg 26(3): 529-35, 2017.

Freedman BR, Fryhofer GW, Salka NS, Raja HA, Hillin CD, Nuss CA, Farber DC, Soslowsky LJ: Mechanical, histological, and functional properties remain inferior in conservatively treated Achilles tendons in rodents: Long term evaluation. J Biomech 56: 55-60, 2017.

Freedman, B.R., Gordon, J.A., Bhatt, P.B., Pardes, A.M., Thomas, S.J.,2, Sarver, J.J., Riggin, C.N., Tucker, J.J., Williams, A.W., Zanes, R.C., Hast, M.W., Farber, D.C., Silbernagel, K.G., Soslowsky, L.J. : Nonsurgical treatment and early return to activity leads to improved Achilles tendon fatigue mechanics and functional outcomes during early healing in an animal model. J Ortho Res 34(12): 2172-80, Dec 2016.

Huegel J, Kim DH, Cirone JM, Pardes AM, Morris TR, Nuss CA, Mauck RL, Soslowsky LJ, Kuntz AF: Autologous tendon-derived cell-seeded nanofibrous scaffolds improve rotator cuff repair in an age-dependent fashion. J Orthop Res Aug 2016.

Tucker, J.J., Cirone, J.M., Morris, T.R., Nuss, C.A., Huegel, J., Waldorff, E.I., Zhang, N., Ryaby, J.T., Soslowsky, L.J.: Pulsed electromagnetic field therapy improves tendon-to-bone healing in a rat rotator cuff repair model. J Orthop Res Jun 2016.

Zhang, K., Asai, S., Hast, M.W., Liu, M., Usami, Y., Iwamoto, M., Soslowsky, L.J., Enomoto-Iwamoto, M.: Tendon mineralization is progressive and associated with deterioration of tendon biomechanical properties, and requires BMP-Smad signaling in the mouse Achilles tendon injury model. Matrix Bio 52-54: 315-24, May-Jul 2016.

Marinovich, R., Soenjaya, Y., Wallace, G.Q., Zuskov, A., Dunkman, A., Foster, B.L., Ao, M., Bartman, K., Lam, V., Rizkalla, A., Beier, F., Somerman, M.J., Holdsworth, D.W., Soslowsky, L.J., Lagugné-Labarthet, F., Goldberg, H.A.: The role of bone sialoprotein in the tendon-bone insertion. Matrix biology 53-54: 325-38, 2016.

Connizzo, B.K., Adams, S.M., Adams, T.H., Jawad, A.F., Birk, D.E., Soslowsky, L.J.: Multiscale Regression Modeling in Mouse Supraspinatus Tendons Reveals That Dynamic Processes Act as Mediators in Structure-Function Relationships. J of Biomechanics 49(9), 2016.

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Last updated: 01/22/2018
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