Perelman School of Medicine at the University of Pennsylvania

McKay Orthopaedic Research Laboratory

Faculty

Lachlan James Smith

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Research Assistant Professor of Neurosurgery
Department: Neurosurgery

Contact information
424 Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104
Education:
B.E. (Mechatronic Engineering)
University of Adelaide, 2001.
Ph.D. (Pathology)
University of Adelaide, 2008.
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Selected Publications

Smith LJ, Chiaro JC, O'Donnell P, Ponder KP, Malhotra NR, Elliott DM, Shore EM, Haskins ME: Effects of Neonatal Enzyme Replacement Therapy and Simvastatin Treatment on Cervical Spine Disease in Mucopolysaccharidosis I Dogs. World Symposium on Lysosomal Diseases, San Diego, USA 2014 Notes: Poster.

Chiaro JC, O'Donnell P, Malhotra NR, Ponder KP, Haskins ME, Smith LJ : Effects of Combined Neonatal Enzyme Replacement Therapy and Simvastatin Treatment on Cervical Spine Intervertebral Disc Disease in Mucopolysaccharidosis I. 60th Annual Meeting, Orthopaedic Research Society, New Orleans, USA 2014 Notes: Poster.

Han WM, Marcozzi AN, Lewis JD, Smith LJ, Mauck RL, Elliott DM: Proteoglycan-Rich Micro-Domains Increase in Number and Size with Development and Age in Outer Meniscus. 60th Annual Meeting, Orthopaedic Research Society, New Orleans, USA 2014 Notes: Poster.

Chiaro JA, O'Donnell P, Malhotra NR, Ponder KP, Haskins ME, Smith LJ: Combined Neonatal Enzyme Replacement Therapy and Simvastatin for Treatment of Cervical Spine Intervertebral Disc Disease in Mucopolysaccharidosis I Dogs. American Association of Neurological Surgeons Annual Meeting, San Francisco, USA 2014 Notes: Podium.

Showalter BL, Milby AH, Haughan J, Mauck RL, Elliott DM, Malhotra NR, Schaer TP, Smith LJ: Percutaneous Delivery of Chondroitinase ABC for Initiation of Disc Degeneration in a Goat Model. American Association of Neurological Surgeons Annual Meeting, San Francisco, USA 2014 Notes: Poster.

Showalter BL, Elliott DM, Chen W, Smith LJ, Malhotra NR: Injectable Hydrogel Treatment Stabilizes Human Disc Range of Motion Under Physiologic Cyclic Loading. American Association of Neurological Surgeons Annual Meeting, San Francisco, USA 2014 Notes: Poster.

Martin JT, Milby AH, Chiaro JA, Kim DH, Smith HE, Smith LJ, Elliott DM, Mauck RL: Translation of an Engineered Nanofibrous Disc-like Angle Ply Structure for Intervertebral Disc Replacement. 60th Annual Meeting, Orthopaedic Research Society, New Orleans, USA 2014 Notes: Poster.

del Alcazar CM, Chiaro JA, Shore EM, Haskins ME, Smith LJ : Delayed Chondrocyte Differentiation and Altered Indian Hedgehog Signaling Contribute to Failed Vertebral Bone Formation in Mucopolysaccharidosis VII. 60th Annual Meeting, Orthopaedic Research Society, New Orleans, USA 2014 Notes: Podium.

Kim DH, Smith LJ, Elliott DM, Mauck RL: Maturation and Material Dependent Response of AF and NP Cells to Mechanical Perturbation. 60th Annual Meeting, Orthopaedic Research Society, New Orleans, USA 2014 Notes: Poster.

Smith LJ, Gorth DJ, Showalter BL, Chiaro JA, Beattie EE, Chen W, Elliott DM, Mauck RL, Malhotra NR: In Vitro Characterization of a Stem Cell-Seeded Triple Interpenetrating Network Hydrogel for Functional Regeneration of the Nucleus Pulposus. Tissue Engineering. Tissue Engineering: Part A In Press, 2014.

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Last updated: 04/14/2014
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