Perelman School of Medicine at the University of Pennsylvania

McKay Orthopaedic Research Laboratory

Faculty

Lachlan James Smith

faculty photo
Research Assistant Professor of Neurosurgery
Department: Neurosurgery

Contact information
424 Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104
Education:
B.E. (Mechatronic Engineering)
University of Adelaide, 2001.
Ph.D. (Pathology)
University of Adelaide, 2008.
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Selected Publications

Peck SH, O’Donnell PJ, Chiaro JA, Shore EM, Pacifici M, Haskins ME, Malhotra NR, Smith LJ: Pinpointing the Earliest Manifestations of Bone Disease in Mucopolysaccharidosis Disorders. Orthopaedic Research Society Annual Meeting 2015 Notes: Poster.

Lothstein KE, O’Donnell PJ, Peck SH, Dodge GR, Mauck RL, Malhotra NR, Smith LJ: Preconditioning Stem Cells to Maximize Regenerative Potential in the Challenging Microenvironment of the Intervertebral Disc. Orthopaedic Research Society Annual Meeting 2015 Notes: Poster.

Martin JT, Ikuta K, Kim DH, Pfeifer CG, Smith LJ, Elliott DM, Smith HE, Mauck RL: Growth Trajectory and In vivo Implantation of Cellular Nanofibrous Disc-like Angle Ply Structures for Total Disc Replacement. Orthopaedic Research Society Annual Meeting 2015 Notes: Podium.

Smith LJ, Gorth DJ, Showalter BL, Chiaro JA, Beattie EE, Chen W, Elliott DM, Mauck RL, Malhotra NR: In Vitro Characterization of a Stem Cell-Seeded Triple Interpenetrating Network Hydrogel for Functional Regeneration of the Nucleus Pulposus. Tissue Engineering. Tissue Engineering: Part A 20(13-14): 1841-1849, Jul 2014.

Martin JT, Milby AH, Chiaro JA, Kim DH, Hebela NM, Smith LJ, Elliott DM, Mauck RL: Translation of an Engineered Nanofibrous Disc-like Angle Ply Structure for Intervertebral Disc Replacement in a Small Animal Model. Acta Biomaterialia 10(6): 2473-2481, June 2014.

Smith LJ, Chiaro JC, O'Donnell P, Ponder KP, Malhotra NR, Elliott DM, Shore EM, Haskins ME: Effects of Neonatal Enzyme Replacement Therapy and Simvastatin Treatment on Cervical Spine Disease in Mucopolysaccharidosis I Dogs. World Symposium on Lysosomal Diseases, San Diego, USA 2014 Notes: Poster.

Showalter BL, Elliott DM, Chen W, Smith LJ, Malhotra NR: Injectable Hydrogel Treatment Stabilizes Human Disc Range of Motion Under Physiologic Cyclic Loading. American Association of Neurological Surgeons Annual Meeting, San Francisco, USA 2014 Notes: Poster.

Martin JT, Milby AH, Chiaro JA, Kim DH, Smith HE, Smith LJ, Elliott DM, Mauck RL: Translation of an Engineered Nanofibrous Disc-like Angle Ply Structure for Intervertebral Disc Replacement. 60th Annual Meeting, Orthopaedic Research Society, New Orleans, USA 2014 Notes: Poster.

del Alcazar CM, Chiaro JA, Shore EM, Haskins ME, Smith LJ : Delayed Chondrocyte Differentiation and Altered Indian Hedgehog Signaling Contribute to Failed Vertebral Bone Formation in Mucopolysaccharidosis VII. 60th Annual Meeting, Orthopaedic Research Society, New Orleans, USA 2014 Notes: Podium.

Kim DH, Smith LJ, Elliott DM, Mauck RL: Maturation and Material Dependent Response of AF and NP Cells to Mechanical Perturbation. 60th Annual Meeting, Orthopaedic Research Society, New Orleans, USA 2014 Notes: Poster.

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Last updated: 11/14/2014
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