Andrea L. Stout, Ph.D.
Adjunct Assistant Professor of Cell and Developmental Biology
Department: Cell and Developmental Biology
Contact information
421 Curie Boulevard
1107 Biomedical Research Building II/III
Philadelphia, PA 19104
1107 Biomedical Research Building II/III
Philadelphia, PA 19104
Office: 215-573-3942
Publications
Education:
BA (Physics)
Lawrence University, 1986.
Ph.D. (Biophysics)
The University of Michigan, Ann Arbor, 1993.
Permanent linkBA (Physics)
Lawrence University, 1986.
Ph.D. (Biophysics)
The University of Michigan, Ann Arbor, 1993.
Description of Research Expertise
My expertise is in light microscopy, with special emphasis on confocal and super-resolution microscopy. My background is in physics and biophysics, specifically using optical methods to probe cellular and molecular dynamics. As Director of the CDB Microscopy Core, I combine these skills with my experience and interest in science education to provide training and imaging services on a variety of cutting-edge commercial microscopes to the Penn research community.Selected Publications
Huang Jianhe, Min Lu Min, Cheng Lan, Yuan Li-Jun, Zhu Xiaoquing, Stout Andrea L, Chen Mary, Li Jian, Parmacek Michael S: Myocardin is required for cardiomyocyte survival and maintenance of heart function. Proceedings of the National Academy of Sciences of the United States of America 106(44): 18734-9, Nov 2009.Liu Fang, Levin Mark D, Petrenko Nataliya B, Lu Min Min, Wang Tao, Yuan Li Jun, Stout Andrea L, Epstein Jonathan A, Patel Vickas V: Histone-deacetylase inhibition reverses atrial arrhythmia inducibility and fibrosis in cardiac hypertrophy independent of angiotensin. Journal of molecular and cellular cardiology 45(6): 715-23, Dec 2008.
Granger Anne, Abdullah Ibrahim, Huebner Faith, Stout Andrea, Wang Tao, Huebner Thomas, Epstein Jonathan A, Gruber Peter J: Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 22(10): 3549-60, Oct 2008.
Stout Andrea L, Wang Jushuo, Sanger Jean M, Sanger Joseph W: Tracking changes in Z-band organization during myofibrillogenesis with FRET imaging. Cell motility and the cytoskeleton 65(5): 353-67, May 2008.
Sanger Joseph W, Kang Songman, Siebrands Cornelia C, Freeman Nancy, Du Aiping, Wang Jushuo, Stout Andrea L, Sanger Jean M: How to build a myofibril. Journal of muscle research and cell motility 26(6-8): 343-54, 2005.
Stout A L: Detection and characterization of individual intermolecular bonds using optical tweezers. Biophysical journal 80(6): 2976-86, Jun 2001.
Stout A L, Webb W W: Optical force microscopy. Methods in cell biology 55: 99-116, 1998.
Stout A L, Axelrod D: Spontaneous recovery of fluorescence by photobleached surface-adsorbed proteins. Photochemistry and photobiology 62(2): 239-44, Aug 1995.
Stout A L, Axelrod D: Reversible binding kinetics of a cytoskeletal protein at the erythrocyte submembrane. Biophysical journal 67(3): 1324-34, Sep 1994.
Stout A L, Axelrod D: Evanescent field excitation of fluorescence by epi-illumination microscopy. Applied optics 28(24): 5237-42, Dec 1989.