Penn Orthopaedics

Orthopaedic Surgery Faculty

faculty photo

Louis J. Soslowsky, Ph.D.

Fairhill Professor of Orthopaedic Surgery
Director of McKay Orthopaedic Research Laboratory, University of Pennsylvania
Director of Orthopaedic Research, University of Pennsylvania
Member, Institute for Medicine and Engineering, University of Pennsylvania
Director of Basic Science Research, Shoulder and Elbow Service, University of Pennsylvania
Vice Chair for Research, Department of Orthopaedic Surgery, University of Pennsylvania (reappointed 2009)
Professor, Department of Bioengineering, University of Pennsylvania
Fellow, Institute of Aging, University of Pennsylvania
Founding Director, Penn Center for Musculoskeletal Disorders, University of Pennsylvania (Type 1 center designation in 2008)
Member, Institute for Translational Medicine and Therapeutics
Executive Committee, University of Pennsylvania, Department of Bioengineering
Search Committee, University of Pennsylvania, Institute for Regenerative Medicine
Associate Dean for Research Core Facilities, Perelman School of Medicine, University of Pennsylvania
Member, University of Pennsylvania, Animal Program Advisory Committee (APAC), Vice Provost for Research
Department: Orthopaedic Surgery

Contact information
McKay Orthopaedic Research Laboratory
424 Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104-6081
Office: 215-898-8653
Fax: 215-573-2133
Education:
Diploma
East Brunswick High School , 1982.
B.S. (Engineering Mechanics)
Columbia University, 1986.
M.S. (Engineering Mechanics)
Columbia University, 1987.
M.Phil
Columbia University, 1989.
Ph.D. (Engineering Mech./Biomechanics, Mentor: Van C. Mow)
Columbia University, 1991.
Cert. (Academic Medicine Leadership Program)
Wharton School of the University of Pennsylvania , 2008.
Post-Graduate Training
Research Assistant, Bioengineering Institute, Columbia University (Richard Skalak, Advisor), 1983-1986.
Teaching Assistant, Department of Mathematics, Columbia University (David Bayer, Professor), 1984-1985.
Frank E. Stinchfield Research Fellow, Departments of Mechanical Engineering and Orthopaedic Surgery, Columbia University (Van C. Mow, Advisor), 1986-1991.
Certifications
NA, .
Permanent link
 
> Perelman School of Medicine   > Faculty   > Details

Description of Research Expertise

orthopaedic research, orthopaedic biomechanics and tissue engineering, tendons and ligaments, shoulder and elbow

Selected Publications

Andarawis-Puri N, Flatow E L, Soslowsky L J: Tendon basic science: Development, repair, regeneration and healing. J Orthop Res 2015, accepted.

Tucker J, Riggin C, Connizzo B, Mauck R, Steinberg D, Kuntz A, Soslowsky L, Bernstein J: Effect of Overuse-Induced Tendinopathy on Tendon Healing in a Rat Supraspinatus Repair Model. J Orthop Res 2015, accepted.

Seto SP, Parks AN, Qiu Y, Soslowsky LJ, Karas S, Platt MO, Temenoff JS: Cathepsins in Rotator Cuff Tendinopathy: Identification in Human Chronic Tears and Temporal Induction in a Rat Model. Ann Biomed Eng 2015, In press Notes: [Epub ahead of print]

Freedman BR, Zuskov A, Sarver JJ, Buckley MR, Soslowsky LJ: Evaluating changes in tendon crimp with fatigue loading as an ex vivo structural assessment of tendon damage. J Orthop Res 2015, In press.

Reuther Katherine E, Tucker Jennica J, Thomas Stephen J, Vafa Rameen P, Liu Stephen S, Gordon Joshua A, Caro Adam C, Yannascoli Sarah M, Kuntz Andrew F, Soslowsky Louis J: Effect of scapular dyskinesis on supraspinatus repair healing in a rat model. Journal of shoulder and elbow surgery / American Shoulder and Elbow Surgeons ... [et al.] Mar 2015.

Rooney SI, Loro E, Sarver JJ, Peltz CD, Hast MW, Tseng WJ, Kuntz AF, Liu XS, Khurana TS, Soslowsky LJ: Exercise protocol induces muscle, tendon, and bone adaptations in the rat shoulder. Muscles Ligaments Tendons J 4(4): 413-9, 2015.

Sun M, Connizzo BK, Adams SM, Freedman BR, Wenstrup RJ, Soslowsky LJ, Birk DE: Targeted Deletion of Collagen V in Tendons and Ligaments Results in a Classic Ehlers-Danlos Syndrome Joint Phenotype. Am J Pathol In press, 2015 Notes: [Epub ahead of print]

Dunkman, A., Buckley, M.R., Mienaltowski, M.J., Adams, S.M., Thomas, S.J., Satchell, L., Kumar, A., Pathmanathan, L., Beason, D.P., Iozzo, R.V., Birk, D.E., Soslowsky, L.J.: The Tendon Injury Response Is Influenced by Decorin and Biglycan. Ann Biomed Eng 42(3): 619-30, 2014.

Reuther KE, Thomas SJ, Tucker JJ, Sarver JJ, Gray CF, Rooney SI, Glaser DL, Soslowsky LJ.: Disruption of the anterior-posterior rotator cuff force balance alters joint function and leads to joint damage in a rat model. J Orthop Res 32(5): 638-44, 2014.

Beason, D.P.; Tucker, J.J.; Edelstein, L.; Lee, C.S.; Abboud, J.A.; Soslowsky, L.J.: Rat Rotator Cuff Tendon-to-Bone Healing Properties are Adversely Affected by Hypercholesterolemia. J Shoulder Elbow Surg 23(6): 867-72, 2014.

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Last updated: 07/28/2015
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