Penn Orthopaedics

Orthopaedic Surgery Faculty

faculty photo

Louis J. Soslowsky, Ph.D.

Fairhill Professor of Orthopaedic Surgery
Director of McKay Orthopaedic Research Laboratory, University of Pennsylvania
Director of Orthopaedic Research, University of Pennsylvania
Member, Institute for Medicine and Engineering, University of Pennsylvania
Director of Basic Science Research, Shoulder and Elbow Service, University of Pennsylvania
Vice Chair for Research, Department of Orthopaedic Surgery, University of Pennsylvania (reappointed 2009)
Professor, Department of Bioengineering, University of Pennsylvania
Fellow, Institute of Aging, University of Pennsylvania
Founding Director, Penn Center for Musculoskeletal Disorders, University of Pennsylvania (Type 1 center designation in 2008)
Member, Institute for Translational Medicine and Therapeutics
Executive Committee, University of Pennsylvania, Department of Bioengineering
Search Committee, University of Pennsylvania, Institute for Regenerative Medicine
Department: Orthopaedic Surgery

Contact information
McKay Orthopaedic Research Laboratory
424 Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104-6081
Office: 215-898-8653
Fax: 215-573-2133
East Brunswick High School , 1982.
B.S. (Engineering Mechanics)
Columbia University, 1986.
M.S. (Engineering Mechanics)
Columbia University, 1987.
Columbia University, 1989.
Ph.D. (Engineering Mech./Biomechanics, Mentor: Van C. Mow)
Columbia University, 1991.
Cert. (Academic Medicine Leadership Program)
Wharton School of the University of Pennsylvania , 2008.
Post-Graduate Training
Research Assistant, Bioengineering Institute, Columbia University (Richard Skalak, Advisor), 1983-1986.
Teaching Assistant, Department of Mathematics, Columbia University (David Bayer, Professor), 1984-1985.
Frank E. Stinchfield Research Fellow, Departments of Mechanical Engineering and Orthopaedic Surgery, Columbia University (Van C. Mow, Advisor), 1986-1991.
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Permanent link
> Perelman School of Medicine   > Faculty   > Details

Description of Research Expertise

orthopaedic research, orthopaedic biomechanics and tissue engineering, tendons and ligaments, shoulder and elbow

Selected Publications

Reuther KE, Thomas SJ, Tucker JJ, Sarver JJ, Gray CF, Rooney SI, Glaser DL, Soslowsky LJ.: Disruption of the anterior-posterior rotator cuff force balance alters joint function and leads to joint damage in a rat model. J Orthop Res 32(5): 638-44, 2014.

Buckley MR, Evans EB, Matuszewski PE, Chen YL, Satchel LN, Elliott DM, Soslowsky LJ, Dodge GR.: Distributions of types I, II and III collagen by region in the human supraspinatus tendon. Connect Tissue Res 54(6): 374-9, 2013.

Ahmadzadeh, H., Connizzo, B.K., Freedman, B.R., Soslowsky, L.J., Shenoy, V.B.: Determining the Contribution of Glycosaminoglycans to Tendon Mechanical Properties with a Modified Shear-Lag Model. J Biomech 2013.

Beason, DP, Hsu, J.E., Marshall, S.M., McDaniel, A.L., Temel, R.E., Abboud, J.A., Soslowsky, L.J.: Hypercholesterolemia Increases Supraspinatus Tendon Stiffness and Elastic Modulus Across Multiple Species. J Shoulder Elbow Surg 22(5): 681-6, 2013.

Buckley, M.R., Huffman, G.,R., Iozzo, R.V., Birk, D.E., Soslowsky, L.J.: The Location-Specific Role of Proteoglycans in the Flexor Carpi Ulnaris Tendon. Connective Tissue Research 54(6): 367-73, 2013.

Connizzo, B.K., Yannascoli, S.M, Soslowsky, L.J.: Structure–function relationships of postnatal tendon development: A parallel to healing Matrix Biol 32(2): 106-16, 2013.

Buckley, M.R., Sarver, J.J., Freedman, B.R., Soslowsky, L.J: The Dynamics of Collagen Uncrimping and Lateral Contraction in Tendon and the Effect of Ionic Concentration. J Biomech 46(13): 2242-9, 2013.

Buckley MR, Dunkman AA, Reuther KE, Kumar A, Pathmanathan L, Beason DP, Birk DE, Soslowsky LJ: Validation of a Damage Model for Aging and In Vivo Injury of the Murine Patellar Tendon. J of Biomech Eng 135(041005-1), 2013.

Reuther, KE, Thomas, SJ, Sarver, JJ, Tucker, JJ, Lee, CS, Gray, CF, Glaser, DL, Soslowsky, LJ : Effect of Return to Overuse Activity Following an Isolated Supraspinatus Tendon Tear On Adjacent Intact Tendons and Glenoid Cartilage in a Rat Model. J Orthop Res 31(5): 710-5, 2013.

Dunkman AA, Buckley MR, Mienaltowski MJ, Adams S, Thomas SJ, Satchell L, Kumar A, Pathmanathan L, Beason DP, Iozzo RV, Birk DE, Soslowsky LJ: Decorin Expression Is Important for Age-Related Changes in Tendon Structure and Mechanical Properties. Matrix Biol 32(1): 3-13, 2013.

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Last updated: 05/22/2014
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