Louis J. Soslowsky, Ph.D.
Fairhill Professor of Orthopaedic Surgery
Director of McKay Orthopaedic Research Laboratory, University of Pennsylvania
Director of Orthopaedic Research, University of Pennsylvania
Member, Institute for Medicine and Engineering, University of Pennsylvania
Director of Basic Science Research, Shoulder and Elbow Service, University of Pennsylvania
Vice Chair for Research, Department of Orthopaedic Surgery, University of Pennsylvania (reappointed 2009)
Professor, Department of Bioengineering, University of Pennsylvania
Fellow, Institute of Aging, University of Pennsylvania
Founding Director, Penn Center for Musculoskeletal Disorders, University of Pennsylvania (Type 1 center designation in 2008)
Member, Institute for Translational Medicine and Therapeutics
Department: Orthopaedic Surgery
Contact information
McKay Orthopaedic Research Laboratory
424 Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104-6081
424 Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104-6081
Office: 215-898-8653
Fax: 215-573-2133
Fax: 215-573-2133
Email:
soslowsk@mail.med.upenn.edu
soslowsk@mail.med.upenn.edu
Links
Penn Center for Musculoskeletal Disorders
McKay Orthopaedic Research Laboratory
Lou Soslowsky homepage
Penn Center for Musculoskeletal Disorders
McKay Orthopaedic Research Laboratory
Lou Soslowsky homepage
Education:
Diploma
East Brunswick High School , 1982.
B.S. (Engineering Mechanics)
Columbia University, 1986.
M.S. (Engineering Mechanics)
Columbia University, 1987.
M.Phil
Columbia University, 1989.
Ph.D. (Engineering Mech./Biomechanics, Mentor: Van C. Mow)
Columbia University, 1991.
Cert. (Academic Medicine Leadership Program)
Wharton School of the University of Pennsylvania , 2008.
Diploma
East Brunswick High School , 1982.
B.S. (Engineering Mechanics)
Columbia University, 1986.
M.S. (Engineering Mechanics)
Columbia University, 1987.
M.Phil
Columbia University, 1989.
Ph.D. (Engineering Mech./Biomechanics, Mentor: Van C. Mow)
Columbia University, 1991.
Cert. (Academic Medicine Leadership Program)
Wharton School of the University of Pennsylvania , 2008.
Post-Graduate Training
Research Assistant, Bioengineering Institute, Columbia University (Richard Skalak, Advisor), 1983-1986.
Teaching Assistant, Department of Mathematics, Columbia University (David Bayer, Professor), 1984-1985.
Frank E. Stinchfield Research Fellow, Departments of Mechanical Engineering and Orthopaedic Surgery, Columbia University (Van C. Mow, Advisor), 1986-1991.
Research Assistant, Bioengineering Institute, Columbia University (Richard Skalak, Advisor), 1983-1986.
Teaching Assistant, Department of Mathematics, Columbia University (David Bayer, Professor), 1984-1985.
Frank E. Stinchfield Research Fellow, Departments of Mechanical Engineering and Orthopaedic Surgery, Columbia University (Van C. Mow, Advisor), 1986-1991.
Certifications
NA, .
Permanent linkNA, .
Description of Research Expertise
orthopaedic research, orthopaedic biomechanics and tissue engineering, tendons and ligaments, shoulder and elbowSelected Publications
Beason, D., Connizzo, B.K., Dourte, L.M., Mauck, R.L., Soslowsky, L.J., Steinberg, D.R., and Bernstein, J.: Fiber-aligned polymer scaffolds for rotator cuff repair in a rat model. J Shoulder Elbow Surg 21: 245-250, 2012.108. Ansorge, H.L., Adams, S., Birk, D.E., Soslowsky, L.J.: Mechanical, Compositional and structural properties of the post-natal mouse Achilles tendon. Ann Biomed Eng 39: 1904-1911, 2011.
113. Attia, M., Scott, A., Soslowsky, L.J., Duchesnay, A., van Kuppevelt, T., Carpenter, G., Papy-Garcia, D., Courty, J., Tassoni, M-C., and Martelly, I.: Alterations of overused supraspinatus tendon: a possible role of glycosaminoglycans and HARP/Pleiotrophin in early tendon pathology. J Orthop Res 30: 61-71, 2011.
110. Wenstrup, R.J., Smith, S.M., Florer, J.B., Zhang, G., Beason, D.P., Seegmill,er R.E. Sosowsky, L.J., and Birk, D.E.: Regulation of collagen fibril nucleation and initial fibril assembly involves coordinate interactions with collagens V and XI in developing tendon. J Biol Chem Page: 20455-20465, 2011.
Bermudez, D.M., Herdrich, B.J., Xu, J., Lind, R., Beason, D.P., Mitchell, M.E., Soslowsky, L.J., Liechty, K.W.: Impaired biomechanical properties of diabetic skin: Implications in the pathogenesis of diabetic wound complications. Am J Pathol 5: 2215-23, 2011.
Castello-Cros, R., Whitaker-Menezes, D., Molchansky, A. , Purkins, G., Soslowsky, L.J., Beason, D.P., Sotgia, F., Iozzo, R.V., and Lisanti, M.P.: Scleroderma-like properties of skin from caveolin-1 deficient mice: Implications for new treatment strategies in patients with fibrosis and systemic sclerosis. Cell Cycle 13: 2140-50, 2011.
Andarawis-Puri, N.A., Kuntz, A.F., Kim, S-Y., and Soslowsky, L.J.: Effect of anterior supraspinatus tendon partial-thickness tears on infraspinatus tendon strain through a range of joint rotation angles. J Shoulder Elbow Surg 19: 617-621, 2010.
Peltz, C.D., Sarver, J.J., Dourte, L.M., Wuergler-Hauri, C.C., Williams, G.R., and Soslowsky, L.J.: Exercise following a short immobilization period is detrimental to tendon properties and joint mechanics in a rat rotator cuff injury model. J Orthop Res 28: 841-845, 2010.
Dourte, L.M., Perry, S.M., Getz, C.L., and Soslowsky, L.J.: Tendon properties remain altered in a chronic rat rotator cuff model. Clin Orthop Rel Res 468: 1485-1492, 2010.
Sarver, J.J., Dishowitz, M.I., Kim, S.Y., Soslowsky, L.J.: Transient decreases in forelimb gait and ground reaction forces following rotator cuff injury and repair in a rat model. J Biomech 43: 778-782, 2010.