Robert L Mauck
Associate Professor of Orthopaedic Surgery
Assistant Professor , Department of Bioengineering, School of Engineering and Applied Science, University of Pennsylvania
Member, Institute for Translational Medicine and Therapeutics
Member, Penn Center for Musculoskeletal Disorders
Member, Institute for Medicine and Engineering
Member, Institute on Aging
Member, Institute for Regenerative Medicine
Co-Director, Mckay Orthopaedic Research Laboratory, Tissue Culture Facility
Founding Member, Executive Committee, Center for Engineering Cells and Regeneration (CECR)
Department: Orthopaedic Surgery
Contact information
424 Stemmler Hall
McKay Orthopaedic Research Laboratory
36th Street and Hamilton Walk
Philadelphia, PA 19104-6081
McKay Orthopaedic Research Laboratory
36th Street and Hamilton Walk
Philadelphia, PA 19104-6081
Office: 215-898-8653
Fax: 215-573-2133
Fax: 215-573-2133
Email:
lemauck@mail.med.upenn.edu
lemauck@mail.med.upenn.edu
Publications
Education:
B.A. (Biochemistry)
Columbia University, 1998.
B.S. (Biomedical Engineering)
Columbia University, 1998.
MS (Biomedical Engineering)
Columbia University, 2000.
Ph.D. (Biomedical Engineering)
Columbia University, 2003.
Permanent linkB.A. (Biochemistry)
Columbia University, 1998.
B.S. (Biomedical Engineering)
Columbia University, 1998.
MS (Biomedical Engineering)
Columbia University, 2000.
Ph.D. (Biomedical Engineering)
Columbia University, 2003.
Description of Itmat Expertise
Dr. Mauck works on tissue engineering of the soft tissues of the musculoskeletal system (articular cartilage, intervertebral disc, and knee meniscus) using adult stem cells, novel scaffolding environments, and mechanical bioreactor systems.Selected Publications
Ionescu Lara C, Lee Gregory C, Sennett Brian J, Burdick Jason A, Mauck Robert L: An anisotropic nanofiber/microsphere composite with controlled release of biomolecules for fibrous tissue engineering. Biomaterials 31(14): 4113-20, May 2010.Huang Alice H, Stein Ashley, Mauck Robert Leon: Evaluation of the complex transcriptional topography of mesenchymal stem cell chondrogenesis for cartilage tissue engineering. Tissue engineering. Part A Apr 2010.
Metter Robert B, Ifkovits Jamie L, Hou Kevin, Vincent Ludovic, Hsu Benjamin, Wang Louis, Mauck Robert L, Burdick Jason A: Biodegradable fibrous scaffolds with diverse properties by electrospinning candidates from a combinatorial macromer library. Acta biomaterialia 6(4): 1219-26, Apr 2010.
Nerurkar Nandan L, Sen Sounok, Huang Alice H, Elliott Dawn M, Mauck Robert L: Engineered Disc-Like Angle-Ply Structures for Intervertebral Disc Replacement. Spine 35(8): 867-73, Mar 2010.
Huang Alice H, Farrell Megan J, Kim Minwook, Mauck Robert L: Long-term dynamic loading improves the mechanical properties of chondrogenic mesenchymal stem cell-laden hydrogel. European cells & materials 19: 72-85, Feb 2010.
Maher S A, Mauck R L, Rackwitz L, Tuan R S: A nanofibrous cell-seeded hydrogel promotes integration in a cartilage gap model. Journal of tissue engineering and regenerative medicine 4(1): 25-9, Jan 2010.
Baker Brendon M, Nathan Aswhin S, Gee Albert O, Mauck Robert L: The influence of an aligned nanofibrous scaffold topography on human mesenchymal stem cell fibrochondrogenesis. Biomaterials 2010 Notes: in press.
Erickson IE, van Veen SC, Sengupta S, Kestle SR, Burdick JA, Mauck RL: Age-dependent mesenchymal stem cell chondrogenesis in 3D culture systems. Clinical Orthopaedics and Related Research in press, 2010.
Nerurkar Nandan L, Baker Brendon M, Sen Sounok, Wible Emily E, Elliott Dawn M, Mauck Robert L: Nanofibrous biologic laminates replicate the form and function of the annulus fibrosus. Nature materials 8(12): 986-92, Dec 2009.
Baker Brendon M, Nerurkar Nandan L, Burdick Jason A, Elliott Dawn M, Mauck Robert L: Fabrication and modeling of dynamic multipolymer nanofibrous scaffolds. Journal of biomechanical engineering 131(10): 101012, Oct 2009.