Elizabeth McDonald

faculty photo
Assistant Professor of Radiology at the Hospital of the University of Pennsylvania
Director, Breast Imaging Fellowship, University of Pennsylvania
Department: Radiology

Contact information
Hospital of the University of Pennsylvania
3400 Spruce Street, 1 Silverstein
PHILADELPHIA, PA 19104
Education:
BA (Biochemistry (magna cum laude))
Harvard University, 1995.
PhD (Molecular Neuroscience)
Mayo Graduate School of Medicine, 2003.
MD
Mayo Medical School, 2003.
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Description of Itmat Expertise

My interests involve translational research with the aim of early detection of breast cancer and individualized treatment targeting tumor specific gene expression while minimizing whole body toxicity.

Selected Publications

McDonald ES, Mankoff DA, Mach RH: Novel strategies for breast cancer imaging: new imaging agents to guide treatment. J Nuc Med 57: 69S-74S, Feb 2016 Notes: doi: 10.2967/jnumed.115.157925.

McDonald ES, McCarthy AM, Akhtar A, Synnestvedt A, Schnall M, Conant EF: Baseline screening mammography: Performance of full field digital versus digital breast tomosynthesis. American Journal of Roentgenology 205(5): 1143-8, Nov 2015 Notes: doi: 10.2214/AJR.15.14406.

McDonald ES, Oustimov A, Weinstein SP, Synnestvedt M, Schnall MD, Conant EF: Effectiveness of Tomosynthesis in combination with digital mammography: Outcomes analysis from three years of breast cancer screening. JAMA Onclology 2015 Notes: In Press.

McDonald ES, Clark A, Tchou J, Zhang, P, Freedman, G.: Clinical diagnosis and management of breast cancer. J Nuc Med 57: 9S-16S, Feb 2016 Notes: doi: 10.2967/jnumed.115.157834.

McDonald ES, Hammersley JA, Chou S-H, Rahbar H, Scheel JR, Lee CI, Liu C-L, Lehman CD, Partridge SC.: Performance of diffusion-weighted magnetic resonance imaging as a rapid, non-contrast technique for detecting mammographically occult breast cancer in elevated-risk women with dense breasts. American Journal of Roentgenology 2016 Notes: In Press.

Pertuz S, McDonald ES, Weinstein SP, Conant EC, Kontos D: Fully-automated quantitative estimation of volumetric breast density from digital breast tomosynthesis images: Preliminary results and comparison with digital mammography and magnetic resonance imaging. Radiology Page: 150277, Oct 2015 Notes: epub ahead of print.

Chen L, Ray S, Keller BM, Pertuz S, McDonald ES, Conant EF, Kontos D: The Impact of acquisition dose on quantitative breast density estimation with digital mammography: Results from ACRIN PA 4006. Radiology Feb 2016 Notes: In Press.

Mahrooghy M, Ashraf A, Days D, Mcdonald ES, Rosen M, Mies C, Feldman M, Kontos D. : Pharmacokinetic tumor heterogeneity as a prognostic biomarker for classifying breast cancer recurrence risk IEEE Trans Biomed Eng. 62(6): 1585-94, Jun 2015 Notes: doi: 10.1109/TBME.2015.2395812 Featured on Cover.

Makvandi M, Tilahun ED, Lieberman BP, Anderson RC, Zeng C, Xu K, Hou C, McDonald ES, Pryma DA,Mach RH: The sigma-2 receptor as a therapeutic target for drug delivery in triple negative breast cancer. Biochem Biophys Res Commun (BBRC) 467(4): 1070-1075. Nov 2015 Notes: doi: 10.1016/j.bbrc.2015.09.157.

Mitsumori LM, McDonald ES, Wilson GJ, Neligan PC, Minoshima S, Maki JH: MR Lymphangiography: How I do it. J Magn Reson Imaging 42(6): 1465-77, Dec 2015 Notes: doi: 10.1002/jmri.24887.

McDonald ES, Schopp JG, Peacock S, DeMartini WB, Rahbar H, Lehman CD, Partridge SC: Diffusion-weighted MRI: association between patient characteristics and apparent diffusion coefficients of normal breast fibroglandular tissue at 3 T. AJR Am J Roentgenol 202(5): W496-502, May 2014 Notes: doi: 10.2214/AJR.13.11159.

Clark AS, McDonald ES, Lynch MC, Mankoff D: Using nuclear medicine imaging in clinical practice: update on PET to guide treatment of patients with metastatic breast cancer. Oncology 28(5): 424-30, May 2014.

Doot RK, McDonald ES, Mankoff DA: Role of PET quantitation in the monitoring of cancer response to treatment: review of approaches and human clinical trials. Clin Transl Imaging 2(4): 295-303, Aug 2014.

Patridge SC, McDonald ES: Diffusion weighted magnetic resonance imaging of the breast: protocol optimization, interpretation, and clinical applications. Magn Reson Imaging Clin N Am 21(3): 601-624, Aug 2013 Notes: doi: 10.1016/j.mric.2013.04.007.

Lowenfeld, L, Zaheer, S., Fracol, M., Datta, J, Xu, S., Fitzpatrick, E. DeMichele, A, Zhang, P, McDonald, ES, Czerniecki, B. : Combination anti-Estrogen therapy and anti-HER2 peptide-pulsed DC vaccination improves pathologic complete response in ER+/HER2+ breast cancer patients. Society of Surgical Oncology March 2016 Notes: Abstract accepted to a plenary session for the Society of Surgical Oncology, March 4th, 2016.

Mirzabeigi MN, McDonald ES, Chu MW, Fischer JP, Basta M, Kovach S, Wu LC, Serletti J, Kanchwala S: Operative management of locoregional cancer recurrence following post-mastectomy breast reconstruction-indications and outcomes. American Society for Reconstructive Microsurgery 2016.

Derakhshan JJ, McDonald ES, Siegelman ES, Schnall MD, Wehrli FW: Chemical shift artifact of the third kind: Implications for gradient-echo based contrast enhanced imaging. Accepted for ISMRM 2016.

Cruz, L, McDonald, ES, Mick, R, Czerneicki, B. : Anti-HER2 Th1 Response is Superior to Breast MRI in Response to Neoadjuvant Chemotherapy in Patients with HER2 Positive Breast Cancer. Society of Surgical Oncology 2015 Notes: Abstract accepted to a plenary session for the Society of Surgical Oncology, March 4th, 2016.

McDonald, ES, Assistant Editor (Radiology), Editor in chief, Litin, S. Mayo Clinic.: Mayo Clinic Family Health Book 4th Edition. Mayo Clinic, Rochester, MN 4th Edition, 2009.

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Last updated: 02/10/2016
The Trustees of the University of Pennsylvania