Elizabeth McDonald

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Assistant Professor of Radiology at the Hospital of the University of Pennsylvania
Active Radiologist, Penn Presbyterian Medical Center
Active Radiologist, Pennsylvania Hospital
Attending, Hospital of the University of Pennsylvania
Department: Radiology

Contact information
Hospital of the University of Pennsylvania
3400 Spruce Street, 1 Silverstein
Philadelphia, PA 19104
BA (Biochemistry (magna cum laude))
Harvard University, 1995.
Mayo Medical School, 2003.
PhD (Molecular Neuroscience)
Mayo Graduate School of Medicine, 2003.
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Description of Itmat Expertise

My interests involve translational research with the aim of early detection of breast cancer and personalized cancer treatment.

Selected Publications

McDonald ES, Mankoff DA, Mach RH: Novel strategies for breast cancer imaging: new imaging agents to guide treatment. J Nuc Med 57: 69S-74S, Feb 2016 Notes: doi: 10.2967/jnumed.115.157925.

McDonald ES, McCarthy AM, Akhtar A, Synnestvedt A, Schnall M, Conant EF: Baseline screening mammography: Performance of full field digital versus digital breast tomosynthesis. American Journal of Roentgenology 205(5): 1143-8, Nov 2015 Notes: doi: 10.2214/AJR.15.14406.

McDonald ES, Oustimov A, Weinstein SP, Synnestvedt M, Schnall MD, Conant EF: Effectiveness of digital breast tomosynthesis compared with digital mammography: Outcomes analysis from 3 years of breast cancer screening. JAMA Oncology 2(6), Jun 2016 Notes: doi: 10.1001/jamaoncol.2015.5536 published online Feb 18, 2016.

McDonald ES, Clark A, Tchou J, Zhang, P, Freedman, G.: Clinical diagnosis and management of breast cancer. J Nuc Med 57: 9S-16S, Feb 2016 Notes: doi: 10.2967/jnumed.115.157834.

McDonald ES, Hammersley JA, Chou SS, Rahbar H, Scheel JR, Lee CI, Liu CL, Lehman CD, Partridge SC.: Performance of DWI as a Rapid Unenhanced Technique for Detecting Mammographically Occult Breast Cancer in Elevated-Risk Women with Dense Breasts. AJR Am Journal of Roentgenol Page: W1-W12, Apr 2016 Notes: epub ahead of print.

Chen L, Ray S, Keller BM, Pertuz S, McDonald ES, Conant EF, Kontos D: The Impact of acquisition dose on quantitative breast density estimation with digital mammography: Results from ACRIN PA 4006. Radiology Mar 2016 Notes: epub ahead of print.

Rahbar, H, McDonald, ES, Lee, JM, Partridge, SC, Lee, CI.: How Can Advanced Imaging Be Used to Mitigate Potential Breast Cancer Overdiagnosis? Academic Radiology Mar 2016 Notes: epub ahead of print doi: 10.1016/j.acra.2016.02.008.

Mahrooghy M, Ashraf A, Days D, Mcdonald ES, Rosen M, Mies C, Feldman M, Kontos D. : Pharmacokinetic tumor heterogeneity as a prognostic biomarker for classifying breast cancer recurrence risk IEEE Trans Biomed Eng. 62(6): 1585-94, Jun 2015 Notes: doi: 10.1109/TBME.2015.2395812 Featured on Cover.

Makvandi, M, Xu, K, Lieberman, BP, Anderson, R, Effron, SS, Winters, H, Zeng, C, McDonald, ES, Pryma, DA, Greenberg, RA, Mach, RH.: A radiotracer strategy to quantify PARP-1 expression in vivo provides a biomarker that can enable patient selection for PARP inhibitor therapy. Cancer Research June 2016 Notes: Jun 3. pii: canres.0416.2016. [Epub ahead of print]

Makvandi M, Tilahun ED, Lieberman BP, Anderson RC, Zeng C, Xu K, Hou C, McDonald ES, Pryma DA,Mach RH: The sigma-2 receptor as a therapeutic target for drug delivery in triple negative breast cancer. Biochem Biophys Res Commun (BBRC) 467(4): 1070-1075. Nov 2015 Notes: doi: 10.1016/j.bbrc.2015.09.157.

Pertuz S, McDonald ES, Weinstein SP, Conant EC, Kontos D: Fully-automated quantitative estimation of volumetric breast density from digital breast tomosynthesis images: Preliminary results and comparison with digital mammography and magnetic resonance imaging. Radiology Page: 150277, Oct 2015 Notes: epub ahead of print.

Mitsumori LM, McDonald ES, Wilson GJ, Neligan PC, Minoshima S, Maki JH: MR Lymphangiography: How I do it. J Magn Reson Imaging 42(6): 1465-77, Dec 2015 Notes: doi: 10.1002/jmri.24887.

McDonald ES, Schopp JG, Peacock S, DeMartini WB, Rahbar H, Lehman CD, Partridge SC: Diffusion-weighted MRI: association between patient characteristics and apparent diffusion coefficients of normal breast fibroglandular tissue at 3 T. AJR Am J Roentgenol 202(5): W496-502, May 2014 Notes: doi: 10.2214/AJR.13.11159.

Clark AS, McDonald ES, Lynch MC, Mankoff D: Using nuclear medicine imaging in clinical practice: update on PET to guide treatment of patients with metastatic breast cancer. Oncology 28(5): 424-30, May 2014.

Doot RK, McDonald ES, Mankoff DA: Role of PET quantitation in the monitoring of cancer response to treatment: review of approaches and human clinical trials. Clin Transl Imaging 2(4): 295-303, Aug 2014.

Partridge SC, McDonald ES: Diffusion weighted magnetic resonance imaging of the breast: protocol optimization, interpretation, and clinical applications. Magn Reson Imaging Clin N Am 21(3): 601-624, Aug 2013 Notes: doi: 10.1016/j.mric.2013.04.007.

Lowenfeld, L, Zaheer, S., Fracol, M., Datta, J, Xu, S., Fitzpatrick, E. DeMichele, A, Zhang, P, McDonald, ES, Czerniecki, B. : Combination anti-Estrogen therapy and anti-HER2 peptide-pulsed DC vaccination improves pathologic complete response in ER+/HER2+ breast cancer patients. Society of Surgical Oncology March 2016 Notes: Oral Presentation.

Mirzabeigi MN, McDonald ES, Chu MW, Fischer JP, Basta M, Kovach S, Wu LC, Serletti J, Kanchwala S: Operative management of locoregional cancer recurrence following post-mastectomy breast reconstruction-indications and outcomes. American Society for Reconstructive Microsurgery 2016 Notes: Oral Presentation.

Derakhshan JJ, McDonald ES, Siegelman ES, Schnall MD, Wehrli FW: Chemical shift artifact of the third kind: Implications for gradient-echo based contrast enhanced imaging. Accepted for ISMRM 2016 Notes: Oral Presentation.

Cruz, L, McDonald, ES, Mick, R, Czerneicki, B. : Anti-HER2 Th1 Response is Superior to Breast MRI in Response to Neoadjuvant Chemotherapy in Patients with HER2 Positive Breast Cancer. Society of Surgical Oncology 2015 Notes: Oral Presentation.

McDonald, ES, Assistant Editor (Radiology), Editor in chief, Litin, S. Mayo Clinic.: Mayo Clinic Family Health Book 4th Edition. Mayo Clinic, Rochester, MN 4th Edition, 2009.

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Last updated: 06/17/2016
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