Yanqing Anna Gong

faculty photo
Research Assistant Professor of Medicine
Department: Medicine

Contact information
Perelman School of Medicine at The University of Pennsylvania
Division of Translational Medicine and Human Genetics
Smilow Center for Translational Research, Room 11-142
3400 Civic Center Blvd.
Philadelphia, PA 19104
Pennsylvania, PA 19104
Office: 215-746-3510
Fax: 215-573-8606
Education:
MS (Medicinal Chemistry)
China Pharmaceutical University, China, 2000.
PhD (Pharmacology)
Chinaca Pharmaceutical University, China, 2003.
Permanent link
 

Description of Itmat Expertise

Protease
Inflammation
Stem cell biology
Cardiac repair
Atherosclerosis

Selected Publications

Tao L., Yang J., Cao F., Xie H., Zhang M., Gong Y.*, Zhang C.* : Mogroside IIIE, A novel anti-fibrotic compound, reduces pulmonary fibrosis through Toll like receptor 4 pathways. J Pharmacol. Exp. Ther. in press, 2017 *co-senior author.

Guggilam N., Sannaningaiah D., Gong Y., Grondolsky J., Huang M., Nie H., Davis E., Liu Y., Jenkins M., Strainic J.,Hoover-Plow J. : Cardiac Malformations in EMILIN2 Deficient Mice. Int J Cardiovasc Res 5: 5, 2016.

Huang M., Liu T., Ma P., Mitteer A., Cai, P., Li C., Zhang L., Zhao B., Gong Y. Koumenis, C., Fan Y: c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma. J. Clin. Invest. 126 (5): 1801-14, 2016.

Huang M., Sannaningaiah D., Zhao N., Gong Y., Grondolsky J., Hoover-Plow J: EMILIN2 regulates platelet activation, thrombus formation, and clot retraction. PLoS One. 6;10(2): e0115284, 2015.

Gong Y*, Zhao Y, Li Y, Fan Y, Hoover-Plow J : Plasminogen regulates cardiac repair after myocardial infarction through its noncanonical function in stem cell homing to the infarcted heart. J Am Coll Cardiol 63(25): 2862-2872, Jul 2014 Notes: *Corresponding author.

Huang M, Gong Y, Grondosky J, Hoover-Plow J: Lp(a)/apo(a) modulate MMP-9 activation and neutrophil cytokines in vivo in inflammation to regulate leukocyte recruitment. Am J Pathol 184(5): 1503-1507, May 2014.

Fan Y, Potdar AA, Gong Y, Eswarappa SM, Donnola S, Lathia JD, Hambardzumyan D, Rich JN, Fox PL : Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through HIF-1α accumulation. Nat Cell Biol 16(5): 445-456, May 2014.

Fan Y, Arif A, Gong Y, Jia J, Eswarappa SM, Willard B, Horowitz A, Graham LM, Penn MS, Fox PL. : Stimulus-dependent phosphorylation of profilin-1 in angiogenesis. Nat Cell Biol 14(10): 1046-56, October 2012.

Gong Y, Fan Y, Hoover-Plow J: Plasminogen regulates stromal cell-derived factor-1/CXCR4-mediated hematopoietic stem cell mobilization by activation of matrix metalloproteinase-9. Arterioscler Thromb Vasc Biol 31(9): 2035-43, September 2011.

Gong Y, Hart E, Shchurin A, Hoover-Plow J: Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice. J Clin Invest 118(9): 3012-24, September 2008.

back to top
Last updated: 04/05/2017
The Trustees of the University of Pennsylvania