Charles A. Stanley

Professor of Pediatrics at the Children's Hospital of Philadelphia

Department: Pediatrics

Contact information

Children's Hospital of Philadelphia
34th Street & Civic Center Blvd
Philadelphia, PA 19104

Office: 2155903420
Fax: 2155901605

Education
B.A. (Biochemical Sciences)
Harvard University, 1964.
M.D. (Medicine)
University of Virginia School of Medicine, 1970.

Permanent link

Description of Research Expertise

genetic disorders of carbohydrate and fatty acid metabolism, insulin secretion

Description of Clinical Expertise

hypoglycemia, glycogenoses, fatty acid oxidation disorders, diabetes mellitus

Selected Publications

Suchi M, MacMullen CM, Thornton PA, Adzick NS, Ganguly A, Ruchelli ED, Stanley CA: Molecular and immunohistochemical analyses of the focal form of congenital hyperinsulinism. Mod Path 19: 122-29, 2006.

Lin YU, MacMullen C, Ganguly A, Stanley CA, Shyng SL: A novel KCNJ11 Mutation Associated with congenital hyperinsulinism reduces the intrinsic open probability of beta-cell APT-sensitive potassium channels. J Biol Chem 281(5): 3006-12, Feb 2006.

Li C, Allen A, Kwagh J, Doliba N, Qin W, Najafi H, Collins HW, Matschinsky FM, Stanley CA, Smith TJ: Green tea polypenols modulate insulin secretion by inhibiting glutamate dehydrogenase. Ameri Soc for Biochem and Molec Biol, Inc. Feb 13 2006.

Gloyn AL, Odili S, Zelent D, Castleden HA, Steele AM, Stride A, Magnuson MA, Lorini R, d'Annunzio G, Stanley CA, Kwagh J, van Schaftingen E, Barbetti F, Han Y, Grimsby J, Taub R, Ellard S, Hattersley AT, Matschinsky FM: Insights into the structure and regulation of glucokinase from a novel mutation (V62M) which causes maturity-onset diabetes of the young. J Bio Chem January 2005.

Langdon DR, Odili S, Halaby L, Sayed S, Kwagh J, Buettger C, Zelent D, Matschinsky F, Stanley CA: Insights into the structure and regulation of glucokinase from a novel mutation (M1971) which causes recurrent hyperinsulinemic hypoglycemia. Fellow's Research Poster Day. Children's Hospital of Philadelphia, February 2005.

Li C, Allen A, Kwagh J, Qin W, Collins HW, Matschinsky F, Stanley CA, Smith TJ: Inhibition of glutamate dehydrogenase potentiates glucose stimulated insulin secreation by rat islets. Fellow's Research Poster Day. Children's Hospital of Philadelphia, February 2005.

Raizen DM, Brooks-Kayal A, Steinkrauss L, Tennekoon GI, Stanley CA, Kelly A: Central nervous system hyperexcitability associated with glutamate dehydrogenase gain of function mutations. J Pediatr 146(3): 388-94, March 2005.

Katz LL, Stanley CA: Disorders of Glucose and Other Sugars. Intensive Care of The Fetus & Neonate, 2nd Edition Spitzer MD, Alan (eds.). Elsevier, Inc, Page: 1167-78, Apr 2005.

Steinkrauss L, Lipman TH, Hendell CD, Gerdes M, Thornton PA, Stanley CA: Effects of hypoglycemia on developmental outcome in children with congenital hyperinsulinism. Journal of Pediatric Nursing 20(2), April 2005.

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