faculty photo

Loretta M. Flanagan-Cato


Contact information
D18 Psychology Lab Building
3720 Walnut Street
Philadelphia, PA 19104
Office: 215-898-4085
Fax: 215-898-7301
Graduate Group Affiliations
Education
BA (Psychology)
Rutgers University, 1985.
PhD (Neuroscience)
University of Pittsburgh, 1990.
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Description of Research Expertise

KEY WORDS:
Neuroendocrinology, estrogen, receptors, steroids, neuropeptides, dendritic spines, neuroplasticity

RESEARCH INTERESTS
Steroid-induced plasticity of neural circuits to control reproductive and ingestive behaviors.

RESEARCH TECHNIQUES
Transneuronal viral tracing, immunocytochemistry, cell filling, confocal microscopy, behavioral analysis.

RESEARCH SUMMARY
Our research focuses on the cellular and molecular effects of steroids on brain networks that modulate behaviors such as mating and ingestion. To study these behaviorally-relevant neuro-hormonal interactions, a multidisciplinary approach is required. Thus, techniques ranging from behavioral analysis, immunocytochemical localization of peptide and steroid receptors, transneuronal tracing, and confocal analysis of cell morphology are employed.

Selected Publications

Calizo, L.H. and Flanagan-Cato, L.M. : Estrogen-induced dendrite spine elimination on female rat ventromedial hypothalamic neurons that project to the peri aqueductal gray J. Comparative Neurology 47: 234-248, 2002.

Daniels, D, R.R. Miselis, and L.M. Flanagan-Cato : Transneuronal tracings from sympathetomized lumbar epaxial muscle in female rats. J.Neurobiology 48: 278-290, 2001.

Flanagan-Cato, L.M. : Estrogen-induced remodeling of hypothalamic neural circuitry. Frontiers in Neuroendocrinology 21: 309-329, 2000.

Daniels, D. and L.M. Flanagan-Cato : Functionally-defined compartments of the lordosis neural circuit in the ventromedial hypothalamus in female rats. Journal of Neurobiology 45(1): 1-13, 2000.

Calizo, L.H. and Flanagan-Cato, L.M. : Estrogen selectively regulates spine density within the dendritic arbor of rat ventromedial hypothalamic neurons. J. Neuroscience 20: 1589-96, 2000.

Daniels, D., R.R. Miselis, and L.M. Flanagan-Cato: Central neuronal circuit innervating the lordosis-producing muscles defined by transneuronal transport of pseudorabies virus. J. Neuroscience 19: 2823-33, 1999.

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Last updated: 08/29/2006
The Trustees of the University of Pennsylvania
 
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