Perelman School of Medicine at the University of Pennsylvania

Center for Preventive Ophthalmology and Biostatistics (CPOB)

Grading Protocols

Grading protocols are developed for specific studies depending on the study goals. SIRC currently uses the following grading protocols:


The Complications of AMD Prevention Trial (CAPT) grading protocol quantifies drusen, changes in drusen over time, and describes exudation (late AMD). For a general overview of the CAPT grading protocol click here [PDF currently unavailable].

The Comparison of Age-related Macular Degeneration Treatments Trials (CATT) grading protocol to be added soon.

For a Glossary of Terms Used in Grading AMD see "Glossary of Terms".