*Advance our knowledge of the basic immunology of inflammation, autoimmunity, cancer, transplantation and infection and to translate this new knowledge to novel strategies for diagnosis, prevention and therapeutic intervention.
*Foster collaborations and further strengthen interactions among the Penn community of immunologists.
Spotlights on IFI
*FDA Advisors Say Yes to Personalized Cancer Therapy*
On Wednesday, an FDA advisory committee voted unanimously to approve a personalized cellular therapy – the first of its kind – for pediatric and young adult leukemia developed at Penn Medicine. The vote is the last step before the therapy is formally approved for sale by Novartis, Penn’s collaborator to research and develop CTL019 and other forms of chimeric antigen receptor (CAR) T cell therapy. Carl June, MD, director of the Center for Cellular Therapies in the Abramson Cancer Center, and Stephan Grupp, MD, PhD, director of the Cancer Immunotherapy Frontier Program at Children’s Hospital of Philadelphia, are quoted in extensive national coverage of the vote.
Philadelphia Inquirer • The New York Times • The Washington Post • NPR • Reuters • Wall Street Journal • TIME • NBC News • NBC Nightly News (Clip) • CBS News • Associated Press via ABC News • STAT News • Nature • Fortune • The Hill • Endpoints News • HealthDay News via WebMD
Congratulations Jorge Henao-Mejia!
Jorge Henao-Mejia of the Perelman School of Medicine and Children’s Hospital of Philadelphia has been selected as a Pew Scholar in biomedical sciences for his ongoing work in immunology. His lab uses gene-editing tools to establish the molecular mechanisms involved in the development of chronic inflammatory conditions.
Congratulations to the IFI FY2017 Pilot Awardees!
PI: Dmitry Gabrilovich, MD, PhD: "Characterization of human PMN-MDSC in cancer by using high dimensional approach"
PI: Scott Worthen, MD: "Influenza infection in an autologous human airway-on-a-chip"
Congratulations to Dr. Robert Vonderheide!!
Please join Dr. Wherry in congratulating the following IFI Faculty on their excellent achievements
Dr. Jason Christie has been elected to the Association of American Physicians.
Drs. Paula Oliver and Matthew Weitzman have been appointed Co-Directors of the new Division of Protective Immunity at the Children's Hospital of Philadelphia.
Drs. Carl June, David Porter and Bruce Levine are featured in an episode of National Geographic’s “Breakthrough” series profiling Penn Medicine’s efforts to develop personalized CAR T cell therapies for cancer.
Dr. Carl June's work with Bill Ludwig, the first patient to receive CAR T cell therapy for leukemia as part of a clinical trial, is featured in a Popular Mechanics magazine cover story. It'll Take an Army to Kill the Emperor
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