• Purified human CD8 T-cells

    Erin Zwack/Brodsky Lab & Penn Vet Imaging Core - Murine macrophages infected with Yersinia pseudo tuberculosis. Blue indicates the cell, red is a mitochondrial stain, green is a stain for Yersinia secreted effector proteins.

  • 3D image of the inflamed meningeal membrane of a CX3CR1-GFP reporter mouse

    Claudio Giraudo - Polarization of lytic granules to the immunological synapse during the cytolytic process of human CD8 lymphocytes against cancer cells.

  • Time series of cells expressing GFP-tagged ebola viral protein VP40

    Gretchen Harms, Hunter lab - Stylized images of CD8+ T cells looking at differential localization of the transcription factor T-bet in mouse cells after infection with the parasite Toxoplasma gondii, using the Amnis ImageStream. In the cell in the first and third box, T-bet (red) does not co-localize with DAPI (blue), indicating that it is cytoplas


Our Mission

*Advance our knowledge of the basic immunology of inflammation, autoimmunity, cancer, transplantation and infection and to translate this new knowledge to novel strategies for diagnosis, prevention and therapeutic intervention. 

*Foster collaborations and further strengthen interactions among the Penn community of immunologists.

Spotlights on IFI

Congratulations to our Institute for Immunology Pilot Grant Awardees

PI: Andy Minn, M.D., Ph.D.
"Identifying Mediators of an Interferon-Driven Resistance Program to Immune Checkpoint Blockade in Cancer"

PI: Laura Su, M.D., Ph.D.
"Defining the role of pre-existing memory T cells in human immunization responses to yellow fever vaccine"

Penn Joins Sean Parker Cancer Research Effort

The University of Pennsylvania has joined a first-of-its-kind research collaboration, the Parker Institute for Cancer Immunotherapy, aimed at accelerating the development of new immunotherapies to fight cancer, reportsThe New York Times, the Wall Street Journal and several other national outlets. The venture is backed by a $250 million gift from the Parker Foundation, making it the largest single contribution ever made to the field of immunotherapy.  Carl June, MD,  a professor in Immunotherapy in Pathology and Laboratory Medicine and director of Translational Research in the Abramson Cancer Center, will serve as the Parker Institute’s Penn director. Robert Vonderheide, MD, DPhil, a professor in Cancer Research and associate director of translational research in the ACC, and John Wherry, PhD, a professor of Microbiology and director of Penn’s Institute for Immunology, will serve as co-directors.

Please find all press releases Below:
NY Times
Washington Post
Wall Street Journal
The Verge

2016 IFI Pilot Grant Program RFA 
Applications now being accepted for the 2016 IFI Pilot Grant Program RFA, full RFA listed here
The CyTOF Service Center is now OPEN!

Click here for more details!

Immunology in the News

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