Perelman School of Medicine at the University of Pennsylvania

Penn Institute for Immunology

Director

E. John Wherry, Ph.D.

E. John Wherry, Ph.D.
Richard and Barbara Schiffrin President's Distinguished Professor of Microbiology

One major goal of the research in Dr. Wherry's laboratory is to understand the mechanisms of T cell exhaustion during chronic infections and cancer. A second major interest of the lab is the study of T cell memory including the biology of human T follicular helper cells (TFH). Finally, other ongoing interests in the lab include computational approaches for analysis of high dimensional cytometric, transcriptional, and epigenetic datasets, the origin of CD8 T cell memory, and other models of respiratory and intestinal viral infection.