Featured Publications

Vladimir Muzykantov, M.D., Ph.D., Professor of Medicine and Pharmacology, Director of the Center for Targeted Therapeutics and Translational Nanomedicine (CT3N)
A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation

Guangrui Yang, Ph.D., Research Assistant Professor of Pharmacology
Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival

Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1


Recent Publications

Vladimir Muzykantov, M.D., Ph.D., Professor of Medicine and Pharmacology, Director of the Center for Targeted Therapeutics and Translational Nanomedicine (CT3N)
Dual targeting of therapeutics to endothelial cells: collaborative enhancement of delivery and effect

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Research Areas

A representation of fibrinolysis at a clot by tPA-coupled red blood cells
(see Murciano et al. p 891). Artwork by Erin Boyle. Image of blood clot (c)
PhotoResearchers

Prophylactic fibrinolysis through selective dissolution of nascent clots by
tPA-carrying erythrocytes.

Juan-Carlos Murciano, Sandra Mednilla, Donald Eslin, Elena Atochina,
Douglas B. Cines & Vladimir R. Muztkantov.