Ongoing Efforts in Cardiac Arrest Research
The study of cardiac arrest mechanisms, pathobiology, and management are central to the mission of the Center for Resuscitation Science and have formed the backbone of our research since our founding in 2006. We currently have active studies that span the range of research, from studies of biomarkers to clinical trials in post-cardiac arrest care.
Principal Investigator: Benjamin Abella, MD MPhil
Contact: benjamin.abella@pennmedicine.upenn.edu
Dr. Abella studies sudden cardiac arrest, a leading cause of death that claims over 350,000 lives each year in the United States. Specifically, projects within his clinical research team include: (1) evaluation of CPR and resuscitation performance, (2) testing new methods to teach CPR in the community, (3) prognostication of neurologic outcomes after cardiac arrest, and (4) methods to improve post-arrest care and outcomes. Dr. Abella is also the developer and Medical Director of a novel training course for post-arrest care and targeted temperature management (TTM), the Penn TTM Academy.
Dr. Abella has published over 250 scholarly works, reviews and monographs in numerous professional journals including NEJM, JAMA and Circulation, as well as textbook chapters on cardiac arrest and resuscitation. He is Co-Chair of the global Resuscitation Science Symposium and has participated in developing international CPR guidelines. He has won a number of honors for his research, clinical care in the Emergency Department and his teaching of residents and medical students and has lectured widely on the topics of cardiac arrest and post-arrest treatment. The investigative work of Dr. Abella’s team is supported by funding from the NIH and PCORI, as well as industry sources.
Dr. Abella can be found on Twitter @benjaminabella
Benjamin Abella's Recent Publications
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Anaerobic Lactate Production Is Associated With Decreased Microcirculatory Blood Flow and Decreased Mitochondrial Respiration Following Cardiovascular Surgery With Cardiopulmonary Bypass.
Critical care medicine. 2024 Apr 5; Authors: Greenwood JC, Talebi FM, Jang DH, Spelde AE, Gordon EK, Horak J, Acker MA, Kilbaugh TJ, Shofer FS, Augoustides JGT, Brenner JS, Muzykantov VR, Bakker J, Abella BS -
Machine learning model to predict evolution of pulseless electrical activity during in-hospital cardiac arrest.
Resuscitation plus. 2024 Mar;17:100598 Epub 2024 Mar 8; Authors: Urteaga J, Elola A, Norvik A, Unneland E, Eftestøl TC, Bhardwaj A, Buckler D, Abella BS, Skogvoll E, Aramendi E -
Using generative artificial intelligence in bibliometric analysis: 10 years of research trends from the European Resuscitation Congresses.
Resuscitation plus. 2024 Jun;18:100584 Epub 2024 Feb 22; Authors: Fijačko N, Creber RM, Abella BS, Kocbek P, Metličar Š, Greif R, Štiglic G -
Author Correction: Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.
Nature communications. 2024 Feb 5;15(1):1075; Authors: Axfors C, Schmitt AM, Janiaud P, Van't Hooft J, Abd-Elsalam S, Abdo EF, Abella BS, Akram J, Amaravadi RK, Angus DC, Arabi YM, Azhar S, Baden LR, Baker AW, Belkhir L, Benfield T, Berrevoets MAH, Chen CP, Chen TC, Cheng SH, Cheng CY, Chung WS, Cohen YZ, Cowan LN, Dalgard O, de Almeida E Val FF, de Lacerda MVG, de Melo GC, Derde L, Dubee V, Elfakir A, Gordon AC, Hernandez-Cardenas CM, Hills T, Hoepelman AIM, Huang YW, Igau B, Jin R, Jurado-Camacho F, Khan KS, Kremsner PG, Kreuels B, Kuo CY, Le T, Lin YC, Lin WP, Lin TH, Lyngbakken MN, McArthur C, McVerry BJ, Meza-Meneses P, Monteiro WM, Morpeth SC, Mourad A, Mulligan MJ, Murthy S, Naggie S, Narayanasamy S, Nichol A, Novack LA, O'Brien SM, Okeke NL, Perez L, Perez-Padilla R, Perrin L, Remigio-Luna A, Rivera-Martinez NE, Rockhold FW, Rodriguez-Llamazares S, Rolfe R, Rosa R, Røsjø H, Sampaio VS, Seto TB, Shahzad M, Soliman S, Stout JE, Thirion-Romero I, Troxel AB, Tseng TY, Turner NA, Ulrich RJ, Walsh SR, Webb SA, Weehuizen JM, Velinova M, Wong HL, Wrenn R, Zampieri FG, Zhong W, Moher D, Goodman SN, Ioannidis JPA, Hemkens LG -
Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement from the American Heart Association and Neurocritical Care Society.
Neurocritical care. 2024 Feb;40(1):1-37 Epub 2023 Dec 1; Authors: Hirsch KG, Abella BS, Amorim E, Bader MK, Barletta JF, Berg K, Callaway CW, Friberg H, Gilmore EJ, Greer DM, Kern KB, Livesay S, May TL, Neumar RW, Nolan JP, Oddo M, Peberdy MA, Poloyac SM, Seder D, Taccone FS, Uzendu A, Walsh B, Zimmerman JL, Geocadin RG, American Heart Association, Neurocritical Care Society -
Resuscitative transesophageal echocardiography in emergency departments in the United States and Canada: A cross-sectional survey.
The American journal of emergency medicine. 2024 Feb;76:164-172 Epub 2023 Nov 29; Authors: Teran F, West FM, Jelic T, Taylor L, Jafry ZM, Burns KM, Owyang CG, Emt CC, Abella BS, Andrus P, On behalf ACEP Emergency Ultrasound Section and the Resuscitative TEE Collaborative Registry (rTEECoRe) Investigators -
Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement From the American Heart Association and Neurocritical Care Society.
Circulation. 2024 Jan 9;149(2):e168-e200 Epub 2023 Nov 28; Authors: Hirsch KG, Abella BS, Amorim E, Bader MK, Barletta JF, Berg K, Callaway CW, Friberg H, Gilmore EJ, Greer DM, Kern KB, Livesay S, May TL, Neumar RW, Nolan JP, Oddo M, Peberdy MA, Poloyac SM, Seder D, Taccone FS, Uzendu A, Walsh B, Zimmerman JL, Geocadin RG, American Heart Association and Neurocritical Care Society -
The Latest in Resuscitation Research: Highlights From the 2022 American Heart Association's Resuscitation Science Symposium.
Journal of the American Heart Association. 2023 Dec 5;12(23):e031530 Epub 2023 Dec 1; Authors: Stancati JA, Owyang CG, Araos JD, Agarwal S, Grossestreuer AV, Counts CR, Johnson NJ, Morgan RW, Moskowitz A, Perman SM, Sawyer KN, Yuriditsky E, Horowitz JM, Kaviyarasu A, Palasz J, Abella BS, Teran F -
Can novel multimodal chatbots such as Bing Chat Enterprise, ChatGPT-4 Pro, and Google Bard correctly interpret electrocardiogram images?
Resuscitation. 2023 Dec;193:110009 Epub 2023 Oct 24; Authors: Fijačko N, Prosen G, Abella BS, Metličar Š, Štiglic G -
Impact of Receiving Hospital on Out-of-Hospital Cardiac Arrest Outcome: Racial and Ethnic Disparities in Texas.
Journal of the American Heart Association. 2023 Nov 7;12(21):e031005 Epub 2023 Nov 6; Authors: Huebinger R, Del Rios M, Abella BS, McNally B, Bakunas C, Witkov R, Panczyk M, Boerwinkle E, Bobrow B