Synovial Biopsy, Synovium, Synovial Fluid & Arthrocentesis

Some Life Lessons that I See Suggested from My Electron Micrographs

REACH OUT

This synovial macrophage is reaching out with dramatic processes to enfold a lymphocyte. EM, 7500X..

 

STICK TOGETHER

Platelets sticking together are occluding synovial vessel. Multilaminated basement membrane seems to suggest a wrapping. EM, 5000X.

 

COOPERATE

Activated lymphocytes and adjacent plasma cell with rough endoplasmic reticulum cooperate in stimulation and antibody production. EM, 25,000X..

 

DEPART FROM THE ROUTINE

Very unusual pericyte processes depart from the routine and extend through venule endothelial gaps, EM, 10,000X..

 

HUG

Multiple "arms" from this synovial cell enfold a process from another cell. EM, 30,000 X.

 

TAKE ACTION

This intraluminal leukocyte is degranulating in a vessel wall injured by dense deposits of presumed immune complexes, EM, 6,000X.

 

BE FLEXIBLE

The large cell with profuse polyribosomes is a lymphoblast transformed from a small lymphocyte. EM, 20,000X.

 

TRY TO HEAL

A vessel has been destroyed and is beginning to be replaced by a fibrous scar. EM, 6,000 X.

 

 

BE A BIT MYSTERIOUS AND NOT AFRAID TO BE PUZZLED

What is going on in this cell? EM, 28,000 X.

 

BE PRODUCTIVE

This mast cell produces histamine and other vasoactive substances to act on the adjacent vessel. EM, 10,000 X.

 

H. R. Schumacher, MD

 

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