Synovial Biopsy, Synovium, Synovial Fluid & Arthrocentesis

Miscellaneous Synovium Photo/Slide Viewer

 

References Related to Miscellaneous Features of Synovium

Apatite (Hydroxyapatite)

Reginato AJ, Schumacher HR: Synovial calcification in a patient with collagen vascular disease. Light and electron microscopic studies. J Rheumatol 4:261-271, 1977.

Reginato AJ, Schumacher HR, Brighton C: Experimental hydroxyapatite synovial and articular cartilage calcification. Light and electron microscopic studies. Arthritis Rheum 25:1239-1249, 1982.

Chlamydia (Reactive Arthritis)

Schumacher HR, Magge S, Cherian PV, Sleckman J, Rothfuss S, Clayburne G, Sieck M: Light and electron microscopic studies on the synovial membrane in Reiter's syndrome. Arthritis Rheum 31:937-946, 1988.

Rahman MU, Schumacher HR, Hudson AP: Recurrent arthritis in Reiter's syndrome: A function of inapparent chlamydial infection of the synovium. Sem Arthritis Rheum 21:259-266, 1992.

Rahman MU, Cheema MA, Schumacher HR, Hudson AP:Molecular evidence for the presence of Chlamydia in the synovium of patients with Reiter's syndrome. Arthritis Rheum 35:521-529, 1992.

Beutler AM, Schumacher HR, Whittum-Hudson JA, Salameh WA , Hudson AP: Case report: In situ hybridization for detection of Inapparent infection with Chlamydia trachomatis in synovial tissue of a patient with Reiter’s syndrome. Am J Med Sci 310:206-213, 1995.

Nanagara R, Li F, Beutler A, Hudson A, Schumacher HR: Alteration of chlamydia trachomatis biologic behavior in synovial membranes. Arthritis Rheum 38:1410-1417, 1995.

Branigan PJ, Gerard HC, Hudson AP, Schumacher HR: Comparison of synovial tissue and synovial fluid as the source of nucleic acids for detection of Chlamydia trachomatis by polymerase chain reaction. Arthritis Rheum 39:1740-6, 1996.

Beutler AM, Hudson AP, Whittum-Hudson JA, Salameh WA , Gerard HC, Branigan PJ, Schumacher HR: Chlamydia trachomatis can persist in joint tissue after antibiotic treatment in chronic Reiter's syndrome/Reactive Arthritis. J Clin Rheumatol 3:125-130, 1997.

Gerard HC, Branigan PJ, Schumacher HR, Hudson AP: Synovial Chlamydia trachomatis in patients with reactive arthritis/Reiter’s syndrome are viable but show aberrant gene expression. J Rheumatol 25:734-742, 1998.

Whittum-Hudson JA, Gerard HC, Clayburne G, Schumacher HR and Hudson AP: A non-invasive murine model of chlamydia-induced reactive arthritis. Revue du Rhumatisme 66:50S-56S, 1999.

Kotake S, Schumacher HR, Arayssi TK, Gerard HC, Branigan PJ, Hudson AP, Yarboro CH, Klippel JH, Wilder RL: Gamma interferon and interleukin-10 expression in synovial tissues from patients with early stages of chlamydia-associated arthritis and undifferentiated oligoarthritis and from healthy volunteers. Infection and Immunity 67:2682-86, 1999.

Schumacher HR, Arayssi T, Crane M, Lee J, Gerard H, Hudson AP, Klippel J: Chlamydia trachomatis nucleic acids can be found in the synovium of some asymptomatic subjects. Arthritis Rheum 42:1281-184, 1999.

Schumacher HR, Gerard HC, Arayssi TK, Pando JA, Branigan PJ, Saaibi DL and Hudson AP: Lower prevalence of chlamydia pneumoniae DNA compared with chlamydia trachomatis DNA in synovial tissue of arthritis patients. Arthritis Rheum 42:1889-93, 1999.

Olmez N, Wang GF, Li Y, Zhang H, Schumacher HR: Chlamydial nucleic acids in synovium in osteoarthritis: what are the implications? J Rheumatol 28: 1874-1880, 2001.

Gerard HC, Krausse-Opatz B, Wang Z, Rudy D, Rao JP, Zeidler H, Schumacher HR, Whittum-Hudson JA, Kohler L, Hudson AP: Expression of Chlamydia trachomatis genes encoding products required for DNA synthesis and cell division during active versus persistent infection. Molecular Micribiol 41:731-741, 2001.

Gerard HC, Wang Z, Whittum-Hudson JA, El-Gabalawy H, Goldbach-Mansky R, Bardin T, Schumacher HR, Hudson AP: Cytokine and chemokine mRNA produced in synoval tissue chronically infected with Chlamydia trachomatis and C. pneumoniae. J Rheumatol 29: 1827-1835, 2002.

Gerard HC, Whittum-Hudson JA, Schumacher HR, Hudson AP: Differential expression of three Chlamydia trachomatis hsp60-encoding genes in active vs. persistent infections. Microb Pathog 36:35-39, 2004.

Early arthritis

Goldbach-Mansky R, Lee JM, Hoxworth JM, Smith D 2 nd, Duray P, Schumacher HR, Yarboro CH, Klippel J, Kleiner D, El-Gabalawy H: Active synovial matrix metalloproteinase-2 is associated with radiographic erosions in patients with early synovitis. Arthritis Res 2: 145-153, 2000.

Eosinophilic arthritis

Brogadir SP, Goldwein MI, Schumacher HR: A hypereosinophilic syndrome mimicking rheumatoid arthritis. Am J Med 69:799-802, 1980.

Synovium - General

Dai L, Pessler F, Chen LX, Clayburne G and Schumacher HR. Detection and initial characterization of synovial lining fragments in synovial fluid. Rheumatology Advance Access published Dec. 13, 2005.

Yocum DE, Lafyatis R, Remmers EF, Schumacher HR, Wilder RL: Hyperplastic synoviocytes from rats with streptoccocal cell wall-induced arthritis exhibit a transformed phenotype that is thymic-dependent and retinoid inhibitable. Am J Pathol 132:38-48, 1988.

Infectious arthritis

Schumacher HR: Joint pathology in infectious arthritis. Clin Rheum Dis 4:33-50, 1978.

Friedman HM, Pincus T, Gibilisco P, Baker D, Glazer JP, Plotkin SA, Schumacher HR: Acute monoarticular arthritis caused by herpes simplex virus and cytomegalovirus. Am J Med 69:241-247, 1980.

Schumacher HR: How micro-organisms are handled to localize to joints and within joints. Scand J Rheumatol 24:199-202,1995.

Gérard HC, Wang Z, Wang GF, El-Gabalawy H, Goldbach-Mansky R, Li Y, Majeed W, Zhang H, Ngai N, Hudson AP, Schumacher HR: Chromosomal DNA from a variety of bacterial species is present in synovial tissue from patients with various forms of arthritis. Arthritis Rheum 44: 1689-1697, 2001.

 

Missouri metacarpal syndrome

Williams WV, Clope R, Gaunt WD, Adelstein EH, Hoyt TS, Singh A, Pressly TA, English R, Schumacher HR, Walker SE. Metacarpophalangeal arthropathy associated with manual labor (Missouri metacarpal syndrome). Arthritis Rheum 30:1362-1371, 1987.

Multicentric reticulohistiocytosis

Levin RW, Schumacher HR: Multicentric reticulohistiocytosis. Internal Medicine for the Specialist 10:148-157, 1989.

Raphael SA, Cowdery SL, Faerber EN, Lischner HW, Schumacher HR, Tourtellotte CD: Multicentric reticulohistiocytosis in a child. J Pediatrics 114:266-269, 1989.

Gorman JD, Danning C, Schumacher HR, Klippel JH,Davis JC: Multicentric reticulohistiocytosis. Case report with immunohistochemical analysis and literature review. Arthritis Rheum 43;930-8, 2000.

Shannon SE, Schumacher HR, Self S, Brown AN: Multicentric reticulohistiocytosis responding to tumor necrosis factor-α inhibition in a renal transplant patient.. J Rheum 32:565-567, 2005.

Neuropathic arthropathy

Louthrenoo W, Ostrov BE, Park YS, Rothfuss S, Schumacher HR: Pseudoseptic arthritis:an unusual presentation of neuropathic arthropathy. Case report with studies on synovial membrane and synovial fluid. Ann Rheum Dis 50:717-721, 1991.

Osteoarthritis

Eymontt MJ, Gordon GV, Schumacher HR, Hansell JR: The effects of synovial permeability and synovial fluid leukocyte counts in symptomatic osteoarthritis after intraarticular corticosteroid administration. J Rheumatol 9:198-203, 1982.

Gordon GV, Villanueva T, Schumacher HR, Gohel V: Autopsy study correlating degree of osteoarthritis, synovitis and evidence of articular calcification. J Rheumatol 11:681-686, 1984.

VanLinthoudt D, Beutler A, Clayburne G, Sieck M, Fernandes L, Schumacher HR: Morphometric studies on synovium in advanced osteoarthritis: Is there an association between apatite-like material and collagen deposits? Clin and Exper Rheumatol 15: 493-497, 1997.

Olmez N, Wang GF, Li Y, Zhang H, Schumacher HR: Chlamydial nucleic acids in synovium in osteoarthritis: what are the implications? J Rheumatol 28: 1874-1880, 2001.

Osteochondromatosis

Wise CM, Wheeler GE, Irby WR, Schumacher HR: Synovial osteochondromatosis and pseudogout. J Rheumatol 11:229-232, 1984.

Pachydermoperiostosis

Jojima H, Kinoshita K and Naito M. A case of pachydermoperiostosis treated by oral administrationo f a bisphosphonate and arthroscopic synovectomy. Mod Rheumatol 17:330-332, 2007.

Pancreatic disease

Gibson T, Schumacher HR, Pascual E, Brighton C: Arthropathy, skin and bone lesions in pancreatic disease. J Rheumatol 2:7-13, 1975.

Smukler NM, Schumacher HR, Pascual E, Brown S, Ryan WE, Sedeghian MR: Synovial fat necrosis associated with ischemic pancreatic disease. Arthritis Rheum 22:547-553, 1979.

Polyarteritis

Smukler NM, Schumacher HR: Chronic non-destructive arthritis associated with cutaneous polyarteritis. Arthritis Rheum 20:1114-1120, 1977.

Pseudarthrosis

Heppenstall RB, Brighton CT , Esterhai JL, Katz M, Schumacher HR: Synovial pseudarthrosis: A clinical, roentgenographic-scintigraphic, and pathologic study. J Trauma 27:463-470, 1987.

Sarcoidosis

Palmer DG, Schumacher HR: Synovitis with non-specific histological changes in synovium in chronic . Ann Rheum Dis 43:778-782, 1984.

Sweet's syndrome

Krauser RE, Schumacher HR: The arthritis of Sweet's syndrome. Arth Rheum 18:35-41, 1975.

Synovitis, Early

Schumacher HR, Kitridou RC: Synovitis of recent onset: A clinico-pathologic study during the first month of disease. Arthritis Rheum 15:465-485, 1972.

Pascual E, Steinberg M, Schumacher HR: Restoration of the hip joint space in long-standing rheumatoid arthritis following contralateral cup arthroplasty. Clin Orthop 111:121-123, 1975.

Schumacher HR, Bautista BB, Krauser RE, Mathur AK , Gall EP:Histological appearance of the synovium in early rheumatoid arthritis. Sem Arth Rheum 23:3-10, 1994.

Kotake S, Schumacher HR, Yarboro CH, Arayssi TK, Pando JA, Kanik KS, Gourley MF, Klippel JH, Wilder RL: In vivo gene expression of type 1 and type 2 cytokines in synovial tissues from patients in early stages of rheumatoid, reactive, and undifferentiated arthritis. Proc Assoc of Am Phys 109:286-302,1997.

Littman BH, Schumacher HR, Boyle DL, Weisman MH, Firestein GS: Effect of tenidap on metalloproteinase gene expression in rheumatoid arthritis: A synovial biopsy study. J Clin Rheumatol 3:194-202, 1997.

Fang Q, Sun YY, El-Gabalawy H, Cai W, Ko L, Chin H, Arayssi T, Schumacher HR, Williams WV: Synovial T Cell receptor heterogeneity in early arthritis. Pathobiology 67:59-74,1999.

Kotake S, Schumacher HR, Arayssi TK, Gerard HC, Branigan PJ, Hudson AP, Yarboro CH, Klippel JH, Wilder RL: Gamma interferon and interleukin-10 expression in synovial tissues from patients with early stages of chlamydia-associated arthritis and undifferentiated oligoarthritis and from healthy volunteers. Infection and Immunity 67:2682-86, 1999.

Goldbach-Mansky R, Lee JM, Hoxworth JM, Smith D 2 nd, Duray P, Schumacher HR, Yarboro CH, Klippel J, Kleiner D, El-Gabalawy H: Active synovial matrix metalloproteinase-2 is associated with radiographic erosions in patients with early synovitis. Arthritis Res 2: 145-153, 2000.

Singh JA, Pando JA, Tomaszewski J, Schumacher HR: Quantitative analysis of immunohistologic features of very early rheumatoid synovitis in disease modifying antirheumatic drug- and corticosteroid-naïve patients. J Rheum 31:1281-1285, 2004.

Syphilis

Reginato AJ, Schumacher HR, Jimenez S, Maurer K: Synovitis in secondary syphilis. Clinical, light and electron microscopic studies. Arthritis Rheum 22:170-176, 1979.

Thalassemia

Dorwart B, Schumacher HR: Arthritis of B-thalassemia trait: Clinical and pathologic study. Ann Rheum dis 40:185-189, 1981.

Turner’s syndrome

Zulian F, Schumacher HR, Calore A, Goldsmith DP, Athreya BH: Juvenile arthritis in Turner’s syndrome: A multicenter study. Clin and Exper Rheum 16:489-494, 1998.

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