Publications

Tishkoff. S.A., F. A. Reed, F. R. Friedlaender, C. Ehret, A. Ranciaro, A. Froment, J. B. Hirbo, A. A. Awomoyi, J.M, Bodo, O, Doumbo, M. Ibrahim, A. T. Juma, M.J. Kotze, G. Lema, J. H. Moore, H. Mortensen, T.B. Nyambo, S. A. Omar, K. Powell, G. S Pretorius, Michael W. Smith, Mahamadou A. Thera, Charles Wambebe, James L. Weber, and Scott M. Williams (2009) The genetic structure and history of Africans and African Americans. Science 324:1035 – 1044. supplemental files.

Henn BM, Gignoux C, Lin AA, Oefner PJ, Shen P, Scozzari R, Cruciani F, Tishkoff SA, Mountain JL, Underhill PA. (2008)  Y-chromosomal evidence of a pastoralist migration through Tanzania to southern Africa.  Proc Natl Acad Sci.  Aug 5;105(31):10693-8.

Campbell MC, Tishkoff SA. (2008) African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping.  Annu Rev Genomics Hum Genet.;9:403-33. Review.

Sirugo G, Hennig BJ, Adeyemo AA, Matimba A, Newport MJ, Ibrahim ME, Ryckman KK, Tacconelli A, Mariani-Costantini R, Novelli G, Soodyall H, Rotimi CN, Ramesar RS, Tishkoff SA, Williams SM. (2008)  Genetic studies of African populations: an overview on disease susceptibility and response to vaccines and therapeutics.  Hum Genet.  Jul;123(6):557-98. Epub 2008 May 30. Review. Erratum in: Hum Genet.  Sep;124(2):195.

Tishkoff, S.A, Gonder, M.K, Henn, B.M., Mortensen, H., Fernandopulle, N., GignouxC., Knight, A, Underhill, P.A., Ramakrishnan, U, Reed, F.A., Mountain, J.L. (2007) History of click-speaking populations of Africa inferred from mtDNA and Y chromosome genetic variation. Mol. Bio. Evol, 24(10):2180-2195

Gonder, Mary Katherine, Holly M. Mortensen, Floyd A. Reed, Alexandra de Sousa and Sarah A. Tishkoff (2007) Whole mtDNA genome sequence analysis of ancient african aineages. Mol. Biol. Evol, 24(3):757-768.

Shimada, Makoto.K, Karuna Panchapakesan, Sarah Tishkoff, Alejandro Q. Nato, Jr., and Jody Hey (2007) Divergent haplotypes and human history as revealed in a worldwide survey of X-linked DNA sequence variation. Mol. Bio. Evol, 24(3):687-698.

Tishkoff, S.A., Floyd A. Reed, Alessia Ranciaro, Benjamin F. Voight, Courtney C. Babbitt, Jesse S. Silverman, Kweli Powell, Holly Mortensen, Jibril. B. Hirbo, Maha Osman, Muntaser Ibrahim, Sabah A. Omar, Godfrey Lema, T. B. Nyambo, Jilur Ghori, Suzannah Bumpstead, Jonathan K. Pritchard, Gregory A. Wray, Panos Deloukas. (2007) Convergent adaptation of human lactase persistence in Africans and Europeans. Nature Genetics, 39(1):31-40.

Lind JM, Hutcheson-Dilks HB, Williams SM, Moore JH, Essex M, Ruiz-Pesini E, Wallace DC, Tishkoff SA, O'Brien SJ, Smith MW. (2007) Elevated male European and female African contributions to the genomes of African American individuals. Hum Genet. 120(5):713-722.

Tishkoff, S.A. and M.K. Gonder (2006) Human origins within and out of Africa. In: Anthropological Genetics, (M. Crawford, ed), Cambridge University Press.

Reed, F.A. and S.A. Tishkoff (2006) African human diversity, origins, and migrations. Current Opinion in Genetics and Development, 16(6):597-605.

Verrelli BC, Tishkoff SA, Stone AC, Touchman JW. (2006) Contrasting histories of G6PD molecular evolution and malarial resistance in humans and chimpanzees. Mol Biol Evol. Aug;23(8):1592-1601.

Awomoyi A, G. Sirugo, M.J. Newport, and S.A. Tishkoff “Global distribution of a novel trinucleotide microsatellite polymorphism (ATA)_n in intron 8 of the SLC11A1 gene and susceptibility to pulmonary Tuberculosis”, European J. of Immunogenetics, 33(1):11-5. 2006.

Reed FA, Tishkoff SA. (2006) Positive selection can create false hotspots of recombination. Genetics. 172(3):2011-2014.

Wang J., L. Song, M. K. Gonder, S. Azrak, D. A. Ray, M. A. Batzer, S.A. Tishkoff and P. Liang (2006) “Whole genome computational comparative genomics:  a fruitful approach for ascertaining Alu insertion polymorphisms.” Gene, 365:11-20.

Mekel-Bobrov N, Gilbert SL, Evans PD, Vallender EJ, Anderson JR, Hudson RR, Tishkoff S.A., and Lahn BT. (2005) “Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens. Science, 309:1720 – 1722.

Evans PD, Gilbert SL, Mekel-Bobrov N, Vallender EJ, Anderson JR, Vaez-Azizi LM, Tishkoff SA, Hudson RR, Lahn BT. (2005) “Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans. Science, 309:1717-1720.

Tarazona Santos, E. and S.A. Tishkoff (2005) Divergent patterns of haplotype structure and linkage disequilibrium at Interleukin-13 (IL13) in globally diverse human populations”, Genes and Immunity, 6(1):53-65. 2005.

ShriverMD, Rui Mei, Esteban J. Parra, Vibhor Sonpar, Indrani Halder, Sarah A. Tishkoff, Theodore G. Schurr, Sergev I. Zhadanov, Ludmilla P. Osipova, Tom Brutsaert, Jonathan Friedlaender, Lynn B. Jorde, W. Scott Watkins, Michael J. Bamshad, Gerardo Gutierez, Halina Loi, Hajime Matsuzaki, George Argyropoulos, Jose Fernandez, Rick A. Kittles, Joshua M. Akey, and Keith Jones (2005) "Large-scale SNP analysis reveals clustered and continuous patterns of human genetic variation. Human Genomics, 2:81-89.

Tishkoff S.A. and Kenneth K Kidd (2004) Biogeography of human populations: Implications for race and medicine. Nature Genetics, Suppl 1:S21-27.

Verrelli, B.J. and S.A. Tishkoff (2004) “Signatures of selection and gene conversion associated with human color vision variation.” Am J Hum Genet. 75(3):363-375.

Drousiotou, Anthi, Elias Touma, Nicoletta Andreou, Jacques Loiselet, Michalis Angastiniotis, Brian Verrelli, Sarah Tishkoff (2004) “Molecular characterization of G6PD deficiency in Cyprus. Blood Cells Mol Dis. 33:25-30.

Smith MW, NJ Patterson, JA Lautenberger, AL Truelove, GJ McDonald, BD Kessing, Z Yi, G deThe, M. Essex, P. J. Kanki, JP Phair, JJ Goedert, D Vlahov, RE Ferrell, SM Williams, SA Tishkoff, CA Winkler, FM DeLaVega, T Woodage, D Altshuler, JJ Sninsky, DA Gilbert, DA Hafler, SJ O'Brien, and DE Reich (2004) A high density ancestry map for disease gene discovery in African Americans. Am J Hum Genet. 74(5):1001-1013.

Tishkoff, S.A. and B.J. Verrelli (2004) G6PD deficiency and malarial resistance in humans: insights from evolutionary genetic analyses” In: Evolutionary Aspects of Infectious Disease (K. Dronamraju, ed), Cambridge University Press.

Tishkoff, SA and B.J. Verrrelli (2003) Role of evolutionary history on haplotype block structure in the human genome: implications for disease mapping”, Curr Opin Genet Dev. 13(6):569-575.

Tishkoff, S.A. and B.J. Verrelli (2003) Patterns of human genetic diversity:  Implications for human evolutionary history and human disease”, Ann. Rev. Genomics and Human Genetics 4:293-340.

Verrelli, B J. H. McDonald, G. Argyropoulos, G. Destro-Bisol, A. Froment, A. Drousiotou, G. Lefranc, A.N. Helal, J. Loiselet, S.A. Tishkoff (2002) Evidence for balancing selection from nucleotide sequence analyses of human G6PD. Am J Hum Genet.;71(5):1112-1128.

Tishkoff, S.A. and S.M. Williams (2002) “Genetic Analysis of African populations: Human evolution and complex disease”, Nature Reviews Genetics, 3(8):611-621.

Tishkoff, S.A., R. Varkonyi, N. Cahinhinan, S. Abbes, G. Argyropolous, G. Destro-Bisol, A. Drousiotou, B. Dangerfield, G. LeFranc, J. Loiselet, A. Piro, M. Stoneking, A. Tagarelli, G. Tagarelli, E. Touma, S. Williams, A.G. Clark (2001) “Haplotype diversity and linkage disequilibrium at human G6PD:  recent origin of alleles that confer malarial resistance. Science. Jul 20; 293:455-62. 2001.

Tishkoff SA, Pakstis AJ, Stoneking M, Kidd JR, Destro-Bisol G, Sanjantila A, Lu R, Deinard AS, Sirugo G, Jenkins T, Kidd KK, and Clark AG (2000) “Short tandem-repeat polymorphism/Alu haplotype variation at the PLAT locus: Implications for modern human origins. Am J Hum Genet. Oct;67(4):901-925.

Tishkoff, S.A., A.J. Pakstis, S. Michalatos-Beloin, G. Ruano, and K.K. Kidd (2000) A comparison of molecular and statistical methods for estimating haplotype frequencies as illustrated by highly polymorphic STRP data. Am. J. Hum. Genet. Aug;67(2):518-22, 2000.

Destro-Bisol, G., R. Maviglia, A. Caglia, I. Boschi, G. Spedini, V. Pascali, A.G. Clark, and S.A. Tishkoff (1999) Estimating European admixture in an African American population using microsatellites and a microsatellite haplotype (CD4/Alu). Hum. Genet., 104:149-157.

Zietkiweicz, E., V. Yotova, M. Jarnik, M. Korab-Laskowska, K.K. Kidd, D. Modiano, R. Scozzari, M. Stoneking, S. Tishkoff, M. Batzer, and D. Labuda, (1998) Genetic structure of the ancestral population of modern humans. J. Mol. Evol. 47:146-155.

Tishkoff, S.A., A. Goldman, F. Calafell, W.C. Speed, B. Bonné-Tamir, J.R. Kidd, A.J. Pakstis, T. Jenkins, and K.K. Kidd (1998) A global haplotype analysis of the DM locus: implications for the evolution of modern humans and the origin of myotonic dystrophy mutations Am. J. Hum Genet. 62(6):1389-1402.

Zietkiewicz, E., V. Yotova, M. Jarnik, M. Korab-Laskowska, K.K. Kidd, D. Modiano, R. Scozzari, M. Stoneking, S. Tishkoff, M. Batzer, and D. Labuda (1997) “Nuclear DNA variability data support a recent common origin of Homo sapiens. Gene (205):161-171.

Michalatos-Beloin, S., S.A. Tishkoff, K.L. Bentley, K.K. Kidd, and G. Ruano (1996) Molecular haplotyping of genetic markers 10kb apart by allele-specific long range PCR” Nuc. Acids Res. 24:4841-4843, 1996. (S. Michalotos-Beloin and S.A. Tishkoff contributed equally to this paper).

Risch, N., K.K. Kidd, and S.A. Tishkoff (1996) “Genetic data and the African origin of humans”, Science 274:1548-1549, Nov. 29.

Tishkoff, S.A., K.K. Kidd, and N. Risch (1996) “Interpretations of multiregional evolution. Science 274, Nov. 1, 1996.

Tishkoff, S.A., E. Dietzsch, W. Speed, A.J. Pakstis, K. Cheung, J.R. Kidd, B. Bonné-Tamir, A.S. Santachiara-Benerecetti, P. Moral, E. Watson, M. Krings, S. Pääbo, N. Risch, T. Jenkins, and K.K. Kidd (1996) Global patterns of linkage disequilibrium at the CD4 locus and modern human origins. Science 271(5254):1380-1387.

Tishkoff, S.A., G. Ruano, J.R. Kidd, and K.K. Kidd (1996) Distribution and frequency of a polymorphic Alu insertion at the PLAT locus in humans. Human Genetics 97(6):759-764.

Ruano, G., A.S. Deinard, S. Tishkoff, and K.K. Kidd (1994) Detection of DNA sequence variation via deliberate heteroduplex formation from genomic DNAs amplified En Masse in 'population tubes'. PCR Methods and Applications 3:225-231.