Gregory P Bisson, MD, MSCE
Associate Professor of Medicine (Infectious Diseases)
Department: Medicine
Graduate Group Affiliations
Contact information
832 Blockley Hall
423 Guardian Drive
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania
Philadelphia, PA 19104-6021
423 Guardian Drive
Center for Clinical Epidemiology and Biostatistics
University of Pennsylvania
Philadelphia, PA 19104-6021
Office: 215-573-5811
Fax: 215-573-5315
Fax: 215-573-5315
Education:
BA (Japanese)
University of Wisconsin-Madison, 1992.
MD
University of Minnesota School of Medicine, 1997.
MSCE (Epidemiology)
Perelman School of Medicine, University of Pennsylvania, 2006.
Permanent linkBA (Japanese)
University of Wisconsin-Madison, 1992.
MD
University of Minnesota School of Medicine, 1997.
MSCE (Epidemiology)
Perelman School of Medicine, University of Pennsylvania, 2006.
Description of Research Expertise
My research is dedicated to improving treatment outcomes of patients with HIV and tuberculosis (TB) and other AIDS-associated opportunistic infections. Current research projects are evaluating the relationship between very early virologic and immunologic response to antiretroviral therapy and clinical outcomes in adults with HIV/TB. Many patients with advanced HIV die soon after antiretroviral therapy initiation, and our research group focuses on trying to understand the pathophysiologic and social mechanisms underlying these early deaths. In addition, we are pursuing translational projects evaluating novel host-directed therapies for treatment of drug resistant TB.Selected Publications
M. Marll, S. El Sammak, F. Willis, A. Queiroz, A. Rajaratnam, N. Mofokeng, L. Mngomezulu, P. Maenetje, G. Bisson, S. Auld,: Patterns of pulmonary impairment before and after tuberculosis treatment. Union Conference 2025 Nov 2025.M. Marll, A. Rajaratnam, F. Willis, A. Queiroz, T. Ngwanto, P. Maenetje, L. Jane Choene, R. Ramaite Malemela, R. Nkanyane, G. Bisson, S. Auld,: Trajectories of lung function in people with and without HIV during and after pulmonary tuberculosis treatment. Union Conference 2025 Nov 2025.
Mochankana, Kagiso; Bah, Muhammed; Bisson, Greg; Celso, Khosa; Htet, Kyaw; Meghji, Jamilah; Navuluri, Neelima; Rachow, Andrea; Masekela, Refiloe: Post-Tuberculosis Lung Disease Evaluation in Paediatric National Guidelines: Scoping Review of High-Burden Countries. International Journal of Tuberculosis and Lung Disease Open Sept 2025.
Muhammed S. Bah, Kyaw Ko Ko Htet, Gregory P. Bisson, Celso Khosa, Refiloe Masekela, Jamilah Meghji, Kagiso Mochankana, Andrea Rachow, Neelima Navuluri: Assessment of Comorbidities, Risk Factors, and Post Tuberculosis Lung Disease in National Tuberculosis Guidelines: A Scoping Review. PLOS Global Public Health 5(7): e0004935, Jul 2025 Notes: DOI: 10.1371/journal.pgph.0004935.
Alvaro A. Ordonez, Mboyo-di-tamba Willy Vangu, Anisha Rajaratnam, Nomsa Mofokeng, Lungile Gabuza, Pholo Maenetje, Mariane Le Fur, Sydney B. Montesi, Peter Caravan, Sara C. Auld, Gregory P. Bisson: Collagen-targeted PET/CT imaging of tuberculosis patients. European Respiratory Journal 66(1): 2500195, Jul 2025 Notes: doi: 10.1183/13993003.00195-2025.
Mugoma S, Wiebe D, Larson PS, Li Y, Bisson GP: The impact of COVID-19 and public health measures on homicide and suicide trends in Botswana using an interrupted time series analysis. Inj Epidemiol 12(1): 42, Jul 2025 Notes: DOI: 10.1186/s40621-025-00592-y.
Auld SC, Bisson GP: Post-tuberculosis Sequelae and the Burden of "Long TB": Continuing TB Care after Treatment Completion. American Journal of Respiratory and Critical Care Medicine 211(6): 912-913, June 2025 Notes: doi: 10.1164/rccm.202502-0442ED.
Meghji J, Auld SC, Bisson GP, Khosa C, Masekela R, Navuluri N, Rachow A: Post-tuberculosis lung disease: Towards prevention, diagnosis and care. Lancet Respir Med. 13(5): 460-472, May 2025 Notes: DOI: 10.1016/S2213-2600(24)00429-6.
Auld SC, Queiroz ATL, Araujo-Pereira M, Maenetje P, Mofokeng N, Mngomezulu L, Masilela D, Dobosh B, Tirouvanziam R, Kornfeld H, Andrade B, Bisson GP: Inflammatory profiles in sputum and blood of people with TB with and without HIV coinfection. Tuberculosis 151: 102612, Mar 2025 Notes: DOI: 10.1016/j.tube.2025.102612.
Richterman A, Sinha P, Ivers LC, Gross R, Rantleru T, Tamuhla N, Bisson GP: Food Insecurity and Undernutrition Are Associated With Distinct Immunologic Profiles in People With Tuberculosis and Advanced HIV Starting Antiretroviral Therapy. J Acquir Immune Defic Syndr 95(5): 494-504, Apr 2024 Notes: doi: 10.1097/QAI.0000000000003386.