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E. James Petersson, Ph.D.
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Professor of Chemistry
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Department: Chemistry
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Graduate Group Affiliations
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Contact information
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Room 350 Chemistry 1973 Building
3d 231 South 34th Street
Philadelphia, PA 19104-6323
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3d 231 South 34th Street
Philadelphia, PA 19104-6323
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Office: 215-746-2221
3e Lab: 215-746-8450
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3e Lab: 215-746-8450
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Email:
ejpetersson@sas.upenn.edu
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ejpetersson@sas.upenn.edu
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Publications
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Education:
21 9 A.B. 16 (Chemistry) c
2a Dartmouth College, 1998.
21 a Ph.D. 16 (Chemistry) c
3b California Institute of Technology, 2005.
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Permanent link21 9 A.B. 16 (Chemistry) c
2a Dartmouth College, 1998.
21 a Ph.D. 16 (Chemistry) c
3b California Institute of Technology, 2005.
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14f Riggle Brittany A, Greenberg Mara L, Wang Yanfei, Wissner Rebecca F, Zemerov Serge D, Petersson E James, Dmochowski Ivan J: A cryptophane-based "turn-on" 129Xe NMR biosensor for monitoring calmodulin. Organic & biomolecular chemistry 15(42): 8883-8887, Oct 2017.
181 Ferrie John J, Ieda Naoya, Haney Conor M, Walters Christopher R, Sungwienwong Itthipol, Yoon Jimin, Petersson E James: Multicolor protein FRET with tryptophan, selective coumarin-cysteine labeling, and genetic acridonylalanine encoding. Chemical communications (Cambridge, England) 53(80): 11072-11075, Oct 2017.
173 Po Pengse, Delaney Erin, Gamper Howard, Szantai-Kis D Miklos, Speight Lee, Tu LiWei, Kosolapov Andrey, Petersson E James, Hou Ya-Ming, Deutsch Carol: Effect of Nascent Peptide Steric Bulk on Elongation Kinetics in the Ribosome Exit Tunnel. Journal of molecular biology 429(12): 1873-1888, Jun 2017.
1d4 Sungwienwong Itthipol, Hostetler Zachary M, Blizzard Robert J, Porter Joseph J, Driggers Camden M, Mbengi Lea Z, Villegas José A, Speight Lee C, Saven Jeffery G, Perona John J, Kohli Rahul M, Mehl Ryan A, Petersson E James: Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection. Organic & biomolecular chemistry 15(17): 3603-3610, May 2017.
180 Walters Christopher R, Szantai-Kis D Miklos, Zhang Yitao, Reinert Zachary E, Horne W Seth, Chenoweth David M, Petersson E James: The effects of thioamide backbone substitution on protein stability: a study in α-helical, β-sheet, and polyproline II helical contexts. Chemical science 8(4): 2868-2877, Apr 2017.
175 Lin Yi-Chih, Repollet-Pedrosa Milton H, Ferrie John J, Petersson E James, Fakhraai Zahra: Potential Artifacts in Sample Preparation Methods Used for Imaging Amyloid Oligomers and Protofibrils due to Surface-Mediated Fibril Formation. The journal of physical chemistry. B 121(12): 2534-2542, Mar 2017.
196 Chen Xing, Mietlicki-Baase Elizabeth G, Barrett Taylor M, McGrath Lauren E, Koch-Laskowski Kieran, Ferrie John J, Hayes Matthew R, Petersson E James: Thioamide Substitution Selectively Modulates Proteolysis and Receptor Activity of Therapeutic Peptide Hormones. Journal of the American Chemical Society 139(46): 16688-16695, 11 2017.
1a9 Haney Conor M, Cleveland Christina L, Wissner Rebecca F, Owei Lily, Robustelli Jaclyn, Daniels Malcolm J, Canyurt Merve, Rodriguez Priscilla, Ischiropoulos Harry, Baumgart Tobias, Petersson E James: Site-Specific Fluorescence Polarization for Studying the Disaggregation of α-Synuclein Fibrils by Small Molecules. Biochemistry 56(5): 683-691, 02 2017.
192 Karpowicz Richard J, Haney Conor M, Mihaila Tiberiu S, Sandler Raizel M, Petersson E James, Lee Virginia M-Y: Selective imaging of internalized proteopathic α-synuclein seeds in primary neurons reveals mechanistic insight into transmission of synucleinopathies. The Journal of biological chemistry 292(32): 13482-13497, 08 2017.
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Selected Publications
f8 Haney Conor M, Petersson E James: Fluorescence spectroscopy reveals N-terminal order in fibrillar forms of α-synuclein. Chemical communications (Cambridge, England) Jan 2018.14f Riggle Brittany A, Greenberg Mara L, Wang Yanfei, Wissner Rebecca F, Zemerov Serge D, Petersson E James, Dmochowski Ivan J: A cryptophane-based "turn-on" 129Xe NMR biosensor for monitoring calmodulin. Organic & biomolecular chemistry 15(42): 8883-8887, Oct 2017.
181 Ferrie John J, Ieda Naoya, Haney Conor M, Walters Christopher R, Sungwienwong Itthipol, Yoon Jimin, Petersson E James: Multicolor protein FRET with tryptophan, selective coumarin-cysteine labeling, and genetic acridonylalanine encoding. Chemical communications (Cambridge, England) 53(80): 11072-11075, Oct 2017.
173 Po Pengse, Delaney Erin, Gamper Howard, Szantai-Kis D Miklos, Speight Lee, Tu LiWei, Kosolapov Andrey, Petersson E James, Hou Ya-Ming, Deutsch Carol: Effect of Nascent Peptide Steric Bulk on Elongation Kinetics in the Ribosome Exit Tunnel. Journal of molecular biology 429(12): 1873-1888, Jun 2017.
1d4 Sungwienwong Itthipol, Hostetler Zachary M, Blizzard Robert J, Porter Joseph J, Driggers Camden M, Mbengi Lea Z, Villegas José A, Speight Lee C, Saven Jeffery G, Perona John J, Kohli Rahul M, Mehl Ryan A, Petersson E James: Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection. Organic & biomolecular chemistry 15(17): 3603-3610, May 2017.
180 Walters Christopher R, Szantai-Kis D Miklos, Zhang Yitao, Reinert Zachary E, Horne W Seth, Chenoweth David M, Petersson E James: The effects of thioamide backbone substitution on protein stability: a study in α-helical, β-sheet, and polyproline II helical contexts. Chemical science 8(4): 2868-2877, Apr 2017.
175 Lin Yi-Chih, Repollet-Pedrosa Milton H, Ferrie John J, Petersson E James, Fakhraai Zahra: Potential Artifacts in Sample Preparation Methods Used for Imaging Amyloid Oligomers and Protofibrils due to Surface-Mediated Fibril Formation. The journal of physical chemistry. B 121(12): 2534-2542, Mar 2017.
196 Chen Xing, Mietlicki-Baase Elizabeth G, Barrett Taylor M, McGrath Lauren E, Koch-Laskowski Kieran, Ferrie John J, Hayes Matthew R, Petersson E James: Thioamide Substitution Selectively Modulates Proteolysis and Receptor Activity of Therapeutic Peptide Hormones. Journal of the American Chemical Society 139(46): 16688-16695, 11 2017.
1a9 Haney Conor M, Cleveland Christina L, Wissner Rebecca F, Owei Lily, Robustelli Jaclyn, Daniels Malcolm J, Canyurt Merve, Rodriguez Priscilla, Ischiropoulos Harry, Baumgart Tobias, Petersson E James: Site-Specific Fluorescence Polarization for Studying the Disaggregation of α-Synuclein Fibrils by Small Molecules. Biochemistry 56(5): 683-691, 02 2017.
192 Karpowicz Richard J, Haney Conor M, Mihaila Tiberiu S, Sandler Raizel M, Petersson E James, Lee Virginia M-Y: Selective imaging of internalized proteopathic α-synuclein seeds in primary neurons reveals mechanistic insight into transmission of synucleinopathies. The Journal of biological chemistry 292(32): 13482-13497, 08 2017.
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