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Warren J Leonard, MD
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Adjunct Professor of Pathology and Laboratory Medicine
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Department: Pathology and Laboratory Medicine
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Contact information
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Bldg. 10, Rm. 7B05
4d National Heart, Lung, and Blood Institute, NIH
Bethesda, MD 20892
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4d National Heart, Lung, and Blood Institute, NIH
Bethesda, MD 20892
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Office: 301-496-0098
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32 Fax: 301-402-0971
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Email:
wjl@helix.nih.gov
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wjl@helix.nih.gov
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Education:
21 8 n/a c
3f Massachusetts Institutes of Technology, 1970.
21 7 AB 18 (Mathematics) c
2e Princeton University , 1973.
21 7 MD 15 (Medicine) c
2c Stanford University, 1977.
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Permanent link21 8 n/a c
3f Massachusetts Institutes of Technology, 1970.
21 7 AB 18 (Mathematics) c
2e Princeton University , 1973.
21 7 MD 15 (Medicine) c
2c Stanford University, 1977.
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17a Erdmann R B, Gartner J G, Leonard W J, Ellison C A: Lack of Functional TSLP Receptors Mitigates Th2 Polarization and the Establishment and Growth of 4T1 Primary Breast Tumours but has Different Effects on Tumour Quantities in the Lung and Brain. Scandinavian journal of immunology 78(5): 408-18, Nov 2013.
187 Yamashita Saori, Segawa Ryosuke, Satou Nozomi, Hiratsuka Masahiro, Leonard Warren J, Hirasawa Noriyasu: Induction of Thymic Stromal Lymphopoietin Production by Nonanoic Acid and Exacerbation of Allergic Inflammation in Mice. Allergology international : official journal of the Japanese Society of Allergology Sep 2013.
1c2 Rasheed Mohammed Ata Ur, Latner Donald R, Aubert Rachael D, Gourley Tania, Spolski Rosanne, Davis Carl W, Langley William A, Ha Sang-Jun, Ye Lilin, Sarkar Surojit, Kalia Vandana, Konieczny Bogumila T, Leonard Warren J, Ahmed Rafi: Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells. Journal of virology 87(13): 7737-46, Jul 2013.
160 Schmitz Iwana, Schneider Christoph, Fröhlich Anja, Frebel Helge, Christ Daniel, Leonard Warren J, Sparwasser Tim, Oxenius Annette, Freigang Stefan, Kopf Manfred: IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection. PLoS pathogens 9(5): e1003362, May 2013.
1b6 Ishigame Harumichi, Zenewicz Lauren A, Sanjabi Shomyseh, Licona-Limón Paula, Nakayama Maki, Leonard Warren J, Flavell Richard A: Excessive Th1 responses due to the absence of TGF-β signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis. Proceedings of the National Academy of Sciences of the United States of America 110(17): 6961-6, Apr 2013.
17c Wan Chi-Keung, Oh Jangsuk, Li Peng, West Erin E, Wong Elizabeth A, Andraski Allison B, Spolski Rosanne, Yu Zu-Xi, He Jianping, Kelsall Brian L, Leonard Warren J: The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells. Immunity 38(3): 514-27, Mar 2013.
190 Horikawa Mayuka, Weimer Eric T, DiLillo David J, Venturi Guglielmo M, Spolski Rosanne, Leonard Warren J, Heise Mark T, Tedder Thomas F: Regulatory B cell (B10 Cell) expansion during Listeria infection governs innate and cellular immune responses in mice. Journal of immunology (Baltimore, Md. : 1950) 190(3): 1158-68, Feb 2013.
e8 Liao Wei, Lin Jian-Xin, Leonard Warren J: Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy. Immunity 38(1): 13-25, Jan 2013.
14a Chen Bo, Yi Bing, Mao Rui, Liu Haitao, Wang Jinhua, Sharma Ashok, Peiper Stephen, Leonard Warren J, She Jin-Xiong: Enhanced T cell lymphoma in NOD.Stat5b transgenic mice is caused by hyperactivation of Stat5b in CD8+ thymocytes. PloS one 8(2): e56600, 2013.
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Selected Publications
157 Usategui Alicia, Criado Gabriel, Izquierdo Elena, Del Rey Manuel J, Carreira Patricia E, Ortiz Pablo, Leonard Warren J, Pablos José L: A profibrotic role for thymic stromal lymphopoietin in systemic sclerosis. Annals of the rheumatic diseases 72(12): 2018-23, Dec 2013.17a Erdmann R B, Gartner J G, Leonard W J, Ellison C A: Lack of Functional TSLP Receptors Mitigates Th2 Polarization and the Establishment and Growth of 4T1 Primary Breast Tumours but has Different Effects on Tumour Quantities in the Lung and Brain. Scandinavian journal of immunology 78(5): 408-18, Nov 2013.
187 Yamashita Saori, Segawa Ryosuke, Satou Nozomi, Hiratsuka Masahiro, Leonard Warren J, Hirasawa Noriyasu: Induction of Thymic Stromal Lymphopoietin Production by Nonanoic Acid and Exacerbation of Allergic Inflammation in Mice. Allergology international : official journal of the Japanese Society of Allergology Sep 2013.
1c2 Rasheed Mohammed Ata Ur, Latner Donald R, Aubert Rachael D, Gourley Tania, Spolski Rosanne, Davis Carl W, Langley William A, Ha Sang-Jun, Ye Lilin, Sarkar Surojit, Kalia Vandana, Konieczny Bogumila T, Leonard Warren J, Ahmed Rafi: Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells. Journal of virology 87(13): 7737-46, Jul 2013.
160 Schmitz Iwana, Schneider Christoph, Fröhlich Anja, Frebel Helge, Christ Daniel, Leonard Warren J, Sparwasser Tim, Oxenius Annette, Freigang Stefan, Kopf Manfred: IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection. PLoS pathogens 9(5): e1003362, May 2013.
1b6 Ishigame Harumichi, Zenewicz Lauren A, Sanjabi Shomyseh, Licona-Limón Paula, Nakayama Maki, Leonard Warren J, Flavell Richard A: Excessive Th1 responses due to the absence of TGF-β signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis. Proceedings of the National Academy of Sciences of the United States of America 110(17): 6961-6, Apr 2013.
17c Wan Chi-Keung, Oh Jangsuk, Li Peng, West Erin E, Wong Elizabeth A, Andraski Allison B, Spolski Rosanne, Yu Zu-Xi, He Jianping, Kelsall Brian L, Leonard Warren J: The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells. Immunity 38(3): 514-27, Mar 2013.
190 Horikawa Mayuka, Weimer Eric T, DiLillo David J, Venturi Guglielmo M, Spolski Rosanne, Leonard Warren J, Heise Mark T, Tedder Thomas F: Regulatory B cell (B10 Cell) expansion during Listeria infection governs innate and cellular immune responses in mice. Journal of immunology (Baltimore, Md. : 1950) 190(3): 1158-68, Feb 2013.
e8 Liao Wei, Lin Jian-Xin, Leonard Warren J: Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy. Immunity 38(1): 13-25, Jan 2013.
14a Chen Bo, Yi Bing, Mao Rui, Liu Haitao, Wang Jinhua, Sharma Ashok, Peiper Stephen, Leonard Warren J, She Jin-Xiong: Enhanced T cell lymphoma in NOD.Stat5b transgenic mice is caused by hyperactivation of Stat5b in CD8+ thymocytes. PloS one 8(2): e56600, 2013.
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