Dorian McGavern, PhD
Adjunct Associate Professor of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine
Contact information
National Institutes of Neurologial Disorders and Stroke
National Institutes of Health
Bldg 10, Rm 7C213
10 Center Dr
Bethesda, MD 20892
National Institutes of Health
Bldg 10, Rm 7C213
10 Center Dr
Bethesda, MD 20892
Office: 301-443-7949
Fax: 301-402-1007
Fax: 301-402-1007
Email:
mcgavernd@ninds.nih.gov
mcgavernd@ninds.nih.gov
Education:
BS (Microbiology)
Pennsylvania State University, 1995.
PhD (Molecular Neuroscience)
Mayo Clinic/ Foundation, 2000.
Permanent linkBS (Microbiology)
Pennsylvania State University, 1995.
PhD (Molecular Neuroscience)
Mayo Clinic/ Foundation, 2000.
Selected Publications
Moseman E Ashley, McGavern Dorian B: The great balancing act: regulation and fate of antiviral T-cell interactions. Immunological reviews 255(1): 110-24, Sep 2013.Navarathna Dhammika H M L P, Munasinghe Jeeva, Lizak Martin J, Nayak Debasis, McGavern Dorian B, Roberts David D: MRI confirms loss of blood-brain barrier integrity in a mouse model of disseminated candidiasis. NMR in biomedicine 26(9): 1125-34, Sep 2013.
Nayak Debasis, Johnson Kory R, Heydari Sara, Roth Theodore L, Zinselmeyer Bernd H, McGavern Dorian B: Type I interferon programs innate myeloid dynamics and gene expression in the virally infected nervous system. PLoS pathogens 9(5): e1003395, May 2013.
Zinselmeyer Bernd H, Heydari Sara, Sacristán Catarina, Nayak Debasis, Cammer Michael, Herz Jasmin, Cheng Xiaoxiao, Davis Simon J, Dustin Michael L, McGavern Dorian B: PD-1 promotes immune exhaustion by inducing antiviral T cell motility paralysis. The Journal of experimental medicine 210(4): 757-74, Apr 2013.
Swanson, P., and McGavern, D.B.: “Portals of viral entry into the nervous system”. The Blood-Brain Barrier in Health and Disease. Edited by Katerina Dorovini-Zis (eds.). Science Publishers, Page: In Press, 2013.
Nayak, D., and McGavern, D.B.: Microglia development and function. Ann Rev Immunol. In Press, 2013.
Roth, T.L., Nayak, D., and McGavern, D.B.: Transcranial amelioration of inflammation and cell death following brain injury. Nature In Press, 2013.
Herz Jasmin, Zinselmeyer Bernd H, McGavern Dorian B: Two-photon imaging of microbial immunity in living tissues. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 18(4): 730-41, Aug 2012.
Garidou Lucile, Heydari Sara, Gossa Selamawit, McGavern Dorian B: Therapeutic blockade of transforming growth factor beta fails to promote clearance of a persistent viral infection. Journal of virology 86(13): 7060-71, Jul 2012.
Oldstone Michael B A, Edelmann Kurt H, McGavern Dorian B, Cruite Justin T, Welch Megan J: Molecular anatomy and number of antigen specific CD8 T cells required to cause type 1 diabetes. PLoS pathogens 8(11): e1003044, 2012.