Selected Publications

Jo AY, Xie Y, Wooldridge LM, Rogers SA, Kimmey BA, Rodrigues A, Ortega RAS, Creasy KT, Beier KT, Blendy JA, Corder G.: VTA µ-Opioidergic Neurons Facilitate Low Sociability in Protracted Opioid Abstinence. J Neurosci 45: e1154242025, Apr 2025.

Schneider KM, Cao F, Huang HYR, Chen L, Chen Y, Gong R, Raptis A, Creasy KT, Clusmann J, van Haag F, Koop PH, Guillot A, Luedde T, Loomba R, Francque S, Schneider CV.: The Lipidomic Profile Discriminates Between MASLD and MetALD. Aliment Pharmacol Ther 2025.

Huang HYR, Vitali C, Zhang D, Hand NJ, Phillips MC, Creasy KT, Scorletti E, Park J, Regeneron Centre, Schneider KM, Rader DJ, Schneider CV.: Deep metabolic phenotyping of humans with protein-altering variants in TM6SF2 using a genome-first approach. JHEP Rep 7: 101243, Oct 2024.

Rendel MD, Vitali C, Creasy KT, Zhang D, Scorletti E, Huang H, Seeling KS, Park J, Hehl L, Vell MS, Conlon D, Hayat S; Regeneron Center; Phillips MC, Schneider KM, Rader DJ, Schneider CV.: The common p.Ile291Val variant of ERLIN1 enhances TM6SF2 function and is associated with protection against MASLD. Med 5: 963-980, Aug 2024.

Schophaus S, Creasy KT, Koop PH, Clusmann J, Jaeger J, Punnuru V, Koch A, Trautwein C, Loomba R, Luedde T, Schneider KM, Schneider CV.: Machine learning uncovers manganese as a key nutrient associated with reduced risk of steatotic liver disease. Liver International July 2024.

Leonida Hehl, Kate T Creasy, Cecilia Vitali, Eleonora Scorletti, Katharina S Seeling, Mara S Vell, Miriam D Rendel, Donna Conlon, Marijana Vujkovic, Inuk Zandvakili, Christian Trautwein, Kai M Schneider, Daniel J Rader, Carolin V Schneider: A genome-first approach to variants in MLXIPL and their association with hepatic steatosis and plasma lipids. Hepatology Communications 8(5): e0427, May 2024.

Kahealani Uehara, Won Dong Lee, Megan Stefkovich, Dipsikha Biswas, Dominic Santoleri, Anna Garcia Whitlock, William Quinn, Talia Coopersmith, Kate Townsend Creasy, Daniel J Rader, Kei Sakamoto, Joshua D Rabinowitz, Paul M Titchenell: mTORC1 controls murine postprandial hepatic glycogen synthesis via Ppp1r3b. The Journal of Clinical Investigation 134(7): e173782, April 2024.

Eleonora Scorletti, Yedidya Saiman, Sookyoung Jeon, Carolin V. Schneider, Delfin G. Buyco, Chelsea Lin, Blanca E. Himes, Clementina A. Mesaros, Marijana Vujkovic, Kate Townsend Creasy, Emma E. Furth, Jeffrey T. Billheimer, Nicholas J. Hand, David E. Kaplan, Kyong-Mi Chang, Philip S. Tsao, Julie A. Lynch, Joseph L. Dempsey, Julia Harkin, Susovon Bayen, Donna Conlon, Marie Guerraty, Michael C. Phillips, Daniel J. Rader, Rotonya M. Carr: A missense variant in human perilipin 2 (PLIN2 Ser251Pro) reduces hepatic steatosis in mice. JHEP Reports 6(1): 100902, January 2024.

Rader DJ, Creasy KT.: Yo-yo dieting accelerates cardiovascular disease by reprogramming the immune system. Nature 2024.

Creasy KT, Ren H, Jiang J, Peterson ML, Spear BT.: Elongation of Very Long Chain Fatty Acids Like- 3 (Elovl3) is activated by ZHX2 and is a regulator of cell cycle progression. Am J Physiol Gastrointest Liver Physiol 325: G582-G592, Oct 2023.