Selected Publications

Yamaguchi TN, Houlahan KE, Zhu H, Kurganovs N, Livingstone J, Fox NS, Yuan J, Sietsma Penington J, Jung CH, Schwarz T, Jaratlerdsiri W, van Riet J, Georgeson P, Mangiola S, Taraszka K, Lesurf R, Jiang J, Chow K, Heisler LE, Shiah YJ, Ramanand SG, Clarkson MJ, Nguyen A, Espiritu SMG, Stuchbery R, Jovelin R, HuangV, Bell C, O’Connor E, McCoy PJ, Lalansingh CM, Cmero M, Salcedo A, Chan EKF, Liu LY, Stricker PD, Bhandari V, Bornman RMS, Sendorek DH, Lonie A, Prokopec SD, Fraser M, Peters JS, Foucal A, Mutambirwa SBA, Mcintosh L, Orain M, Wakefield M, Picard V, Park DJ, Hovington H, Kerger M, Bergeron A, Sabelnykova V, Seo JH, Pomerantz MM, Zaitlen N, Waszak SM, Gusev A, Lacombe L, Fradet Y, Ryan A, Kishan AU, Lolkema MP, Weischenfeldt J, Tˆetu B, Costello AJ, Hayes VM, Hung RJ, He HH, McPherson JD, Pasaniuc B, van der Kwast T, Papenfuss AT, Freedman ML, Pope BJ, Bristow RG, Mani RS, Corcoran NM, Reimand J, Hovens CM, Boutros PC: The Germline and Somatic Origins of Prostate Cancer Heterogeneity Cancer Discov Feb 2025.

Abramowitz SA, Boulier K, Keat K, Cardone KM, Shivakumar M, DePaolo J, Judy R, Bermudez F, Mimouni N, Neylan C, Kim D, Rader DJ, Ritchie MD, Voight BF, Pasaniuc B, Levin MG, Damrauer SM; Penn Medicine BioBank: Evaluating Performance and Agreement of Coronary Heart Disease Polygenic Risk Scores. JAMA 333(1): 60-70, Jan 2025.

The PRIMED Consortium: Reducing disparities in polygenic risk assessment. Kullo IJ, Conomos MP, Nelson SC, Adebamowo SN, Choudhury A, Conti D, Fullerton SM, Gogarten SM, Heavner B, Hornsby WE, Kenny EE, Khan A, Khera AV, Li Y, Martin I, Mercader JM, Ng M, Raffield LM, Reiner A, Rowley R, Schaid D, Stilp A, Wiley K, Wilson R, Witte JS, Natarajan P, Polygenic Risk Methods in Diverse Populations (PRIMED) Consortium: The PRIMED Consortium: Reducing disparities in polygenic risk assessment. Am J Hum Genet 111(12): 2594-2606, Dec 2024.

Doyle AE, Bearden CE, Gur RE, Ledbetter DH, Martin CL, McCoy TH Jr, Pasaniuc B, Perlis RH, Smoller JW, Davis LK: Advancing Mental Health Research Through Strategic Integration of Transdiagnostic Dimensions and Genomics. Biol Psychiatry 97(5): 450-460, Oct 2024.

Heffel MG, Zhou J, Zhang Y, Lee DS, Hou K, Pastor-Alonso O, Abuhanna KD, Galasso J, Kern C, Tai CY, Garcia-Padilla C, Nafisi M, Zhou Y, Schmitt AD, Li T, Haeussler M, Wick B, Zhang MJ, Xie F, Ziffra RS, Mukamel EA, Eskin E, Nowakowski, TJ, Dixon JR, Pasaniuc B, Ecker JR, Zhu Q, Bintu B, Paredes MF, Luo C: Temporally distinct 3D multi-omic dynamics in the developing human brain. Nature 635(8038): 481-489, Oct 2024.

Jee YH, Thibord F, Dominguez A, Sept C, Boulier K, Venkateswaran V, Ding Y, Cherlin T, Verma SS, Faro VL, Bartz TM, Boland A, Brody JA, Deleuze JF, Emmerich J, Germain M, Johnson AD, Kooperberg C, Morange PE, Pankratz N, Psaty BM, Reiner AP, Smadja DM, Sitlani CM, Suchon P, Tang W, Tr´egou¨et DA, Z¨ollner S, Pasaniuc B, Damrauer SM, Sanna S, Snieder H; Lifelines Cohort Study; Kabrhel C, Smith NL, Kraft P: INVENT Consortium. Multi-ancestry polygenic risk scores for venous thromboembolism. Hum Mol Genet 33(18): 1584-1591, Sept 2024.

Fu M, Valiente-Banuet L, Wadhwa SS, Pasaniuc B, Vossel K, Chang TS: Improving genetic risk modeling of dementia from real-world data in underrepresented populations. Commun Biol 7(1): 1049, Aug 2024.

Fu M, Valiente-Banuet L, Wadhwa SS; UCLA Precision Health Data Discovery Repository Working Group; UCLA Precision Health ATLAS Working Group; Pasaniuc B, Vossel K, Chang TS.: Improving genetic risk modeling of dementia from real-world data in underrepresented populations. medRxiv 7(1): 1049, Aug 2024.

Hou K, Xu Z, Ding Y, Mandla R, Shi Z, Boulier K, Harpak A, Pasaniuc B: Calibrated prediction intervals for polygenic scores across diverse contexts. Nat Genet 56(7): 1386-1396, Jul 2024.

Hervoso JL, Amoah K, Dodson J, Choudhury M, Bhattacharya A, Quinones-Valdez G, Pasaniuc B*, Xiao X*: Splicing-specific transcriptome-wide association uncovers genetic mechanisms for schizophrenia. Am J Hum Genet 111(8): 1573-1587, Jun 2024.