Faculty

Christopher Thom, MD, PhD

faculty photo
Assistant Professor of Pediatrics
Department: Pediatrics
Graduate Group Affiliations

Contact information
Children's Hospital of Philadelphia
Colket Translational Research Bldg, Room 10-052
3501 Civic Center Blvd
Philadelphia, PA 19104
Philadelphia, PA 19104
Office: 267-760-7684
Education:
BA (Chemistry)
Williams College, 2006.
PhD (Cell and Molecular Biology)
University of Pennsylvania, 2015.
MD (Medicine)
University of Pennsylvania, 2015.
Permanent link
 
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Selected Publications

Gu H, Devine M, Hedrick HL, Rintoul NE, Thom CS: High rate of extreme thrombocytosis indicates bone marrow hyperactivity and splenic dysfunction among congenital diaphragmatic hernia patients. Platelets Page: 1-3, Oct 2021 Notes: doi: 10.1080/09537104.2021.1994546.

Thom CS, Echevarria E, Osborne AD, Carr L, Rubey KM, Salazar E, Callaway D, Pawlowski T, Devine M, Kleinman S, Witmer C, Flibotte J, Lambert MP: Extreme thrombocytosis is associated with critical illness and young age, but not increased thrombotic risk, in hospitalized pediatric patients. Journal of thrombosis and haemostasis 18(12): 3352-3358, Dec 2020 Notes: doi: 10.1111/jth.15103. Epub 2020 Oct 21.

Thom CS, Deshmukh H, Soorikian L, Jacobs I, Fiadjoe J, Lioy J. : Airway emergency management in a pediatric hospital before and during the COVID-19 pandemic. International Journal of Pediatric Otorhinolaryngology 139(110458): doi: 10.1016/j.ijporl.2020.110458, Dec 2020.

Thom CS, Ding Z, Levin MG, Damrauer SM, Lee KM, Lynch JA, Chang KM, Tsao PS, Cho K, Wilson PWF, Assimes TL, Sun YV, O’Donnell CJ: Genetic determinants of increased body mass index mediate the effect of smoking on increased risk for type 2 diabetes risk but not coronary artery disease. Human Molecular Genetics 29(19): 3327-3337, November 2020 Notes: doi: 10.1093/hmg/ddaa193.

Thom CS, Voight BF: Genetic colocalization atlas points to common regulatory sites and genes for hematopoietic traits and hematopoietic contributions to disease phenotypes. BMC Medical Genomics 13(1): 89, June 2020.

Thom CS, Jobaliya CD, Lorenz K, Maguire JA, Gagne A, Gadue P, French DL, Voight BF: Tropomyosin 1 genetically constrains in vitro hematopoiesis. BMC Biology 18(1): 52, May 2020.

Thom CS, Brandsma E, Lambert MP: Thrombocytosis in an infant with a TRPV4 mutation: a case report. Platelets 32(3): 429-431, April 2020 Notes: doi.org/10.1080/09537104.2020.1755644.

Thom CS, Chou ST, French DL: Mechanistic and translational advances using iPSC-derived blood cells. Journal of Experimental Pathology 1(2): 36-44, Mar 2020 Notes: doi: 10.33696/pathology.1.010.

Thom CS, Devine M, Kleinman S, Jensen EA, Lambert MP, Padula MA: Neonatal platelet count trends during inhaled nitric oxide therapy. British Journal of Haematology 188(3): e28-e30, Feb 2020.

Lechauve C, Keith J, Khandros E, Fowler S, Mayberry K, Freiwan A, Thom CS, Delbini P, Romero EB, Zhang J, Motta I, Tillman H, Cappellini MD, Kundu M, Weiss MJ: Unc 51–like autophagy-activating kinase (ULK1) mediates clearance of free α-globin in β-thalassemia. Science Translational Medicine 11(506): doi: 10.1126, August 2019.

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Last updated: 03/31/2022
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