Tejvir S. Khurana, MD, PhD

faculty photo
Professor of Physiology
Department: Physiology
Graduate Group Affiliations

Contact information
Department of Physiology,
University of Pennsylvania,
750 Clinical Research Building (CRB),
415 Curie Boulevard,
Philadelphia, PA 19004-6085
Office: (215) 898-4116
Fax: (215) 573-2273
Lab: (215) 573-2640
Education:
MBBS (Medicine)
Delhi University, 1985.
Ph.D. (Neurobiology)
Harvard University, 1992.
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Description of Research Expertise

muscle, muscular disease, muscular dystrophy, therapeutics, gene therapy, extraocular muscle, transcriptome, proteome, genomics, sports medicine, athletic doping, hypoxia, altitude, respiratory, neuromuscular junctions, synapses.

Selected Publications

Simonson B, Subramanya V, Chan MC, Zhang A, Franchino H, Ottaviano F, Mishra MK, Knight AC, Hunt D, Ghiran I, Khurana TS, Kontaridis MI, Rosenzweig A, Das S: DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress. Sci Signal 10 (468): eaaf5967, 2017.

Loro E, Ramaswamy G, Chandra A, Tseng WJ, Mishra MK, Shore EM, Khurana TS: IL15RA is required for osteoblast function and bone mineralization. Bone 103: 20-30, 2017.

Mishra MK, Loro E, Sengupta K, Wilton SD, Khurana TS: Functional improvement of dystrophic muscle by repression of utrophin: let-7c interaction. PLoS One 12(10): e0182676, 2017.

Loro E, Wang SH, Schwab RJ, Khurana TS: In Vivo Evaluation of the Mechanical and Viscoelastic Properties of the Rat Tongue. J Vis Exp 6: (125), 2017.

Hong S, Zhou W, Fang B, Lu W, Loro E, Damle M, Ding G, Jager J, Zhang S, Zhang Y, Feng D, Chu Q, Dill BD, Molina H, Khurana TS, Rabinowitz JD, Lazar MA, Sun Z: Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion. Nat Med 23: 223-234, 2017.

Arsenault PR, Song D, Chung YJ, Khurana TS, Lee FS: The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α Mol Cell Biol 36(18): 2328-43, 2016.

Stone RA, Cohen Y, McGlinn AM, Davison S, Casavant S, Shaffer J, Khurana TS, Pardue MT, Iuvone PM.: Development of Experimental Myopia in Chicks in a Natural Environment. IOVS 57 (11): 4779-89, 2016.

Frederick DW, Loro E, Liu L, Davila A Jr, Chellappa K, Silverman IM, Quinn WJ 3rd, Gosai SJ, Tichy ED, Davis JG, Mourkioti F, Gregory BD, Dellinger RW, Redpath P, Migaud ME, Nakamaru-Ogiso E, Rabinowitz JD, Khurana TS, Baur JA: Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle. Cell Metab 24(2): 269-82, 2016.

Bird SB, Krajacic P, Sawamoto K, Bunya N, Loro E, Khurana TS.: Pharmacotherapy to protect the neuromuscular junction after acute organophosphorus pesticide poisoning. Ann N Y Acad Sci 1374(1): 86-93, 2016.

Ferretti R, Marques MJ, Khurana TS, Santo Neto H: Expression of calcium-buffering proteins in rat intrinsic laryngeal muscles. Physiol Rep 6: pii: e12409, 2015.

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Last updated: 08/31/2018
The Trustees of the University of Pennsylvania