Faculty
Kyle Bittinger, Ph.D.

Assistant Professor of Pediatrics at the Children's Hospital of Philadelphia
Department: Pediatrics
Graduate Group Affiliations
Contact information
The Children's Hospital of Philadelphia
Microbiome Center
Roberts Center for Pediatric Research
2716 South Street, 14th Floor
Philadelphia, PA 19146-2305
Microbiome Center
Roberts Center for Pediatric Research
2716 South Street, 14th Floor
Philadelphia, PA 19146-2305
Office: 267-425-1641
Email:
bittingerk@email.chop.edu
bittingerk@email.chop.edu
Education:
B.S. (Chemistry)
University of Pittsburgh, 2001.
Ph.D. (Physical Chemistry)
Massachusetts Institute of Technology, 2008.
Permanent linkB.S. (Chemistry)
University of Pittsburgh, 2001.
Ph.D. (Physical Chemistry)
Massachusetts Institute of Technology, 2008.
Selected Publications
Hong G, Lipscombe C, Daniel S, O’Dea A, Bittinger K, Dorgan D, Hadjiliadis D.: CFTR modulation on the microbial environment in cystic fibrosis. Blood 138: 3169, Nov 2022.Firrman J, Liu L, Mahalak K, Tanes C, Bittinger K, Tu V, Bobokalonov J, Mattei L, Zhang H, Van den Abbeele P: The impact of environmental pH on the gut microbiota community structure and short chain fatty acid production. FEMS Microbiol Ecol 98: fiac038, May 2022.
Paraskevopoulou M, Mayer LS, Krueger A, Pattekar A, Ramos A, ... Bittinger K, ... Tomov V, Juarez J.: A single cell approach reveals immune cell dynamics in ulcerative colitis (UC) and highlights association of CD8 intraepithelial lymphocytes (IELS) with response to Vedolizumab treatment. Gastroenterology 167(2): S-1093, May 2022.
Benitez A, Tanes C, Hu W, Friedman ES, Gerber J, Kelly A... Bittinger K, Zemel BS.: Impact of early life antibiotics on the gut microbiome, bile acids, and related gastrointestinal manifestations. Gastroenterology 167(2): S-1010, May 2022.
Zong W, Allu SR, Friedman ES, Firrman J, Tu V, Bittinger K, Liu L, Vinogradov S, Wu GD.: Disruption of intestinal oxygen dynamics during acute colitis alters the gut microbiome. Gastroenterology 162(7): S-511, May 2022.
Lemons JS, Conrad M, Tanes C, Friedman ES, Chau L, Ogawa SA, Curry D, Murphy D, Kachelries K, Bittinger K, Liu LS, Baldassano RN, Wu GD: Intestinal acylcarnitines as a biomarker of IBD and their role in bacterial metabolism. Gastroenterology 162(7): S-222, May 2022.
Kastl A, Zong W, Gershuni V, Friedman ES, Tanes C, Boateng A, O’Connor K, Bittinger K, Terry NA, Bales CB, Albenberg L, Wu GD.: Clinical phenotyping of patients with short bowel syndrome via effects of diet and the gut microbiota on bile acid metabolism. Gastroenterology 162(7): S-653-S-654, May 2022.
Redding LE, Tu V, Abbas A, Alvarez M, Zackular JP, Gu C, Bushman FD, Kelly DJ, Barnhart D, Lee JJ, Bittinger K: Genetic and phenotypic characteristics of Clostridium (Clostridioides) difficile from canine, bovine, and pediatric populations. Anaerobe 74: 102539, Apr 2022.
Mennella JA, Li Y, Bittinger K, Friedman ES, Zhao C, Li H, Wu GD, Trabulsi JC: The Macronutrient Composition of Infant Formula Produces Differences in Gut Microbiota Maturation That Associate with Weight Gain Velocity and Weight Status. Nutrients 14: 1241, Mar 2022.
Breton J, Tanes C, Tu V, Albenberg L, Rowley S, Devas N, Hwang R, Kachelries K, Wu GD, Baldassano RN, Bittinger K, Mattei P: A microbial signature for pediatric perianal Crohn's Disease. J Crohn’s Colitis Page: jjac032, Feb 2022 Notes: Epub Ahead of print.
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