Faculty

Kiran Musunuru, MD, PhD, MPH, ML, MRA

Barry J. Gertz Professor for Translational Research

Department: Medicine

Graduate Group Affiliations

Cell and Molecular Biology

Contact information

Email:
kiranmusunuru@gmail.com

Education:
AB (Biochemical Sciences)
Harvard College, Cambridge, MA, 1997.
PhD (Biomedical Sciences)
The Rockefeller University, New York, NY, 2003.
MD (Medicine)
Weill-Cornell Medical College, New York, NY, 2004.
MPH (Epidemiology)
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2009.
ML (Law)
University of Pennsylvania Law School, Philadelphia, PA, 2019.
MRA (Regulatory Affairs)
Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2024.

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Gurevitz C, Bajaj A, Khera AV, Do R, Schunkert H, Musunuru K, Rosenson RS.: Gene therapy and genome editing for lipoprotein disorders. Eur Heart J Jul 2025.

Shuvaev VV, Tam YK, Lee BW, Myerson JW, Herbst A, Kiseleva RY, Glassman PM, Parhiz H, Alameh MG, Pardi N, Muramatsu H, Shuvaeva TI, Arguiri E, Marcos-Contreras OA, Hood ED, Brysgel TV, Nong J, Papp TE, Eaton DM, Riley R, Palanki R, Musunuru K, Brenner JS, Mitchell MJ, Ferrari VA, Mui BL, Semple SC, Weppler SA, Atluri P, Margulies KB, Weissman D, Muzykantov VR.: Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo. Proc Natl Acad Sci U S A 122: e2409266122, Jul 2025.

Musunuru K, Grandinette SA, Wang X, Hudson TR, Briseno K, Berry AM, Hacker JL, Hsu A, Silverstein RA, Hille LT, Ogul AN, Robinson-Garvin NA, Small JC, McCague S, Burke SM, Wright CM, Bick S, Indurthi V, Sharma S, Jepperson M, Vakulskas CA, Collingwood M, Keogh K, Jacobi A, Sturgeon M, Brommel C, Schmaljohn E, Kurgan G, Osborne T, Zhang H, Kinney K, Rettig G, Barbosa CJ, Semple SC, Tam YK, Lutz C, George LA, Kleinstiver BP, Liu DR, Ng K, Kassim SH, Giannikopoulos P, Alameh MG, Urnov FD, Ahrens-Nicklas RC.: Patient-specific in vivo gene editing to treat a rare genetic disease. N Engl J Med 392: 2235-2243, Jun 2025.

Urnov F, Kassim S, Musunuru K, Liu D, Lee A, Barrera L, Stetkiewicz P, Bruno J, Hewitt M, Lister T, Malech H, Gasch L, Diver M, Gertler N, Grignon F, Le A, Lehmicke M, Almendro-Navarro V, Lembong J.: Advancing gene-editing platforms to improve the viability of rare-disease therapeutics: key insights from a 2024 Scientific Exchange hosted by ARM, ISCT, and Danaher. Cytotherapy Jun 2025.

Musunuru K, Urnov F.: Moving Therapeutic Genome Editing into Global Clinical Trials and Medicine. CRISPR J May 2025.

Musunuru K.: A milestone for gene-editing therapies. N Engl J Med 392: 508-509, Jan 2025.

Allyse MA, Agam P, Bombard Y, Feys R, Horstmann M, Kokayi A, Isasi R, Meagher KM, Michie M, Musunuru K, Ormond KE, Riggan KA, Yap JQ.: Building better medicine: translational justice and the quest for equity in US healthcare. Am J Bioeth 2025.

Kassim SH, Urnov F, Musunuru K, Lee A, Barrera L, Stetkiewicz P, Bruno J, Hewitt M, Lister T, Malech H, Gasch L, Diver M, Gertler N, Grignon F, Le A, Lehmicke M, Horwitz EM, Liu DR, Lembong J, Almendro-Navarro V.: Platform solutions for commercial challenges to expanding patient access and making gene editing sustainable. Nat Biotechnol 2025.

IGVF Consortium: Deciphering the impact of genomic variation on function. Nature 633: 47-57, Sep 2024.

Riggan KA, Feys R, Kokayi A, Meagher KM, Michie M, Musunuru K, Ormond KE, Schelhaas AJ, Yap JQ, Isasi R, Allyse MA.: Grounded in reality: integrating community values and priorities of end users in human gene editing. Am J Bioeth 24: 43-45, Aug 2024.