Kiran Musunuru, MD, PhD, MPH
Associate Professor of Medicine
Department: Medicine
Graduate Group Affiliations
Contact information
3400 Civic Center Blvd, Bldg 421
11-104 Smilow Center for Translational Research
Philadelphia, PA 19104
11-104 Smilow Center for Translational Research
Philadelphia, PA 19104
Office: 215-573-4717
Email:
kiranmusunuru@gmail.com
kiranmusunuru@gmail.com
Education:
AB (Biochemical Sciences)
Harvard College, Cambridge, MA, 1997.
PhD (Biomedical Sciences)
The Rockefeller University, New York, NY, 2003.
MD (Medicine)
Weill-Cornell Medical College, New York, NY, 2004.
MPH (Epidemiology)
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2009.
Permanent linkAB (Biochemical Sciences)
Harvard College, Cambridge, MA, 1997.
PhD (Biomedical Sciences)
The Rockefeller University, New York, NY, 2003.
MD (Medicine)
Weill-Cornell Medical College, New York, NY, 2004.
MPH (Epidemiology)
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2009.
Selected Publications
Musunuru Kiran, Arora Pankaj, Cooke John P, Ferguson Jane F, Hershberger Ray E, Hickey Kathleen T, Lee Jin-Moo, Lima João A C, Loscalzo Joseph, Pereira Naveen L, Russell Mark W, Shah Svati H, Sheikh Farah, Wang Thomas J, MacRae Calum A: Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association. Circulation. Genomic and precision medicine 11(6): e000046, Jun 2018.Li Shuang, Li Mushan, Liu Xiaojian, Yang Yuanyuan, Wei Yuda, Chen Yanhao, Qiu Yan, Zhou Tingting, Feng Zhuanghui, Ma Danjun, Fang Jing, Ying Hao, Wang Hui, Musunuru Kiran, Shao Zhen, Zhao Yongxu, Ding Qiurong: Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator in Hepatic Differentiation of Human Pluripotent Stem Cells. Stem cell reports May 2018.
Musunuru Kiran, Bernstein Daniel, Cole F Sessions, Khokha Mustafa K, Lee Frank S, Lin Shin, McDonald Thomas V, Moskowitz Ivan P, Quertermous Thomas, Sankaran Vijay G, Schwartz David A, Silverman Edwin K, Zhou Xiaobo, Hasan Ahmed A K, Luo Xiao-Zhong James: Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research. Circulation. Genomic and precision medicine 11(4): e002178, Apr 2018.
Musunuru Kiran: Stem cell modeling of lipid genetics. Current opinion in lipidology 29(2): 151-155, Apr 2018.
Small Kerrin S, Todorčević Marijana, Civelek Mete, El-Sayed Moustafa Julia S, Wang Xiao, Simon Michelle M, Fernandez-Tajes Juan, Mahajan Anubha, Horikoshi Momoko, Hugill Alison, Glastonbury Craig A, Quaye Lydia, Neville Matt J, Sethi Siddharth, Yon Marianne, Pan Calvin, Che Nam, Viñuela Ana, Tsai Pei-Chien, Nag Abhishek, Buil Alfonso, Thorleifsson Gudmar, Raghavan Avanthi, Ding Qiurong, Morris Andrew P, Bell Jordana T, Thorsteinsdottir Unnur, Stefansson Kari, Laakso Markku, Dahlman Ingrid, Arner Peter, Gloyn Anna L, Musunuru Kiran, Lusis Aldons J, Cox Roger D, Karpe Fredrik, McCarthy Mark I: Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition. Nature genetics 50(4): 572-580, Apr 2018 Notes: co-senior author.
Musunuru Kiran: How genome editing could be used in the treatment of cardiovascular diseases. Personalized medicine 15(2): 67-69, Mar 2018.
Chadwick Alexandra C, Evitt Niklaus H, Lv Wenjian, Musunuru Kiran: Reduced Blood Lipid Levels With In Vivo CRISPR-Cas9 Base Editing of ANGPTL3. Circulation 137(9): 975-977, Feb 2018.
Zezulin Alexandra, Musunuru Kiran: Turning up the Heat with Therapeutic Epigenome Editing. Cell stem cell 22(1): 10-11, Jan 2018.
Musunuru Kiran, Sheikh Farah, Gupta Rajat M, Houser Steven R, Maher Kevin O, Milan David J, Terzic Andre, Wu Joseph C: Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling and Precision Medicine: A Scientific Statement From the American Heart Association. Circulation. Genomic and precision medicine 11(1): e000043, Jan 2018.
Xu Yu-Xin, Redon Valeska, Yu Haojie, Querbes William, Pirruccello James, Liebow Abigail, Deik Amy, Trindade Kevin, Wang Xiao, Musunuru Kiran, Clish Clary B, Cowan Chad, Fizgerald Kevin, Rader Daniel, Kathiresan Sekar: Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol. Atherosclerosis 268: 196-206, Jan 2018.