Faculty

Daniel P Kelly, MD

faculty photo
Willard and Rhoda Ware Professor of Diabetes and Metabolic Diseases
Department: Medicine
Graduate Group Affiliations

Contact information
3400 Civic Center Blvd.
Smilow Center for Translational Research
11-122
Philadelphia, PA 19104
Office: 215-898-0768
Lab: 215-898-2374
Education:
B.S. (Biology)
University of Illinois, 1978.
M.D. (Medicine )
University of Illinois College of Medicine, Chicago, Illinois, 1982.
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Selected Publications

Zamani P, Proto EA, Wilson N, Fazelinia H, Ding H, Spruce LA, D’Avila Jr A, Mazurek J, Prenner SB, Desjardins B, Margulies KB, Kelly DP, Arany Z, Doulias P-T, Elrod J, Allen ME, McCormack SE, Schur GM, D’Aquilla K, Kumar D, Thakuri D, Prabhakaran K, Langham MC, Poole DC, Seeholzer SH, Reddy R, Ischiropoulos H, Chirinos JA: Multimodality assessment of HFpEF skeletal muscle reveals differences in the machinery of energy fuel metabolism. ESC Heart Failure Aug 2021.

Yurista SR, Chong C-R, Badimon JJ, Kelly DP, de Boer RA, Westenbrink BD: Therapeutic potential of ketone bodies for patients with Cardiovascular disease. J Am Coll Cardiol Apr 2021.

Sharp III TE, Scarborough AL, Li Z, Polhemus DJ, Hidalgo HA, Schumacher JD, Matsuura TR, Jenkins JS, Kelly DP, Goodchild TT, Lefer DJ: Novel Göttingen miniswine model of heart failure with preserved ejection fraction integrating multiple comorbidities. JACC Basic to Translational Science Feb 2021.

Yurista SR, Matsuura TR, Silljé HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, Oberdorf-Maass SU, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD: Ketone ester treatment improves cardiac function and reduces pathologic remodeling in pre-clinical models of heart failure. Circ Heart Failure Jan 2021.

Dierickx P, Jiang C, Xiao Y, Carpenter B, Zhai J, Vermunt MW, Nguyen H, Blobel G, Kelly DP, Pei L, Lazar MA: The circadian REV-ERB nuclear receptors are essential drivers of heart metabolism and function. Nature Cardiovascular Research In press 2021.

Selvaraj S, Margulies K, Dugyala S, Schubert E, Tierney A, Arany Z, Pryma DA, Shah SH, Rame E, Kelly DP, Bravo PE: Comparison of exogenous ketone administration versus dietary carbohydrate restriction on myocardial glucose suppression: A Randomized Clinical Trial. Journal of Nuclear Medicine 2021.

Muoio DM, Recchia FA, and Kelly DP: Comments on Crosstalk 49: Ketone bodies serve as an important fuel for the normal and diseased heart. J of Physiol 2021.

Davidson MT, Grimsrud PA, Lai L, Draper JA, Fisher-Wellman KH, Narowski TM, Koves TR, Kelly DP, Muoio DM: Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure. Circulation Research Sep 2020.

Sakamoto T and Kelly DP: A case for adaptive cardiac hypertrophic remodeling is CITED. Circulation Research Aug 2020.

Tomoya Sakamoto , Timothy R Matsuura , Shibiao Wan , David M Ryba , Junil Kim , Kyoung-Jae Won , Ling Lai , Christopher Petucci , Nataliya Petrenko , Kiran Musunuru , Rick B Vega , and Daniel P Kelly: A Critical Role for Estrogen-related Receptor Signaling in Cardiac Maturation. Circulation Research Jun 2020.

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Last updated: 11/07/2021
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