Faculty
John H. Holmes, PhD, FACE, FACMI, FIAHSI
Professor of Medical Informatics in Epidemiology in Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania
Department: Biostatistics and Epidemiology
Graduate Group Affiliations
Contact information
401 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
423 Guardian Drive
Philadelphia, PA 19104
Office: 215-898-4833
Fax: 215-573-5325
Fax: 215-573-5325
Publications
Education:
A.B. (Sociology)
University of Pennsylvania, 1976.
M.S. (Information Systems)
Drexel University, 1987.
Ph.D. (Information Science)
Drexel University, 1996.
Permanent linkA.B. (Sociology)
University of Pennsylvania, 1976.
M.S. (Information Systems)
Drexel University, 1987.
Ph.D. (Information Science)
Drexel University, 1996.
Description of Research Expertise
medical informatics; data mining; evolutionary computation; machine learning; artificial intelligence; database design and implementation for clinical research; medical decision making;Selected Publications
Lutfi W, Pan Z, Grasty MA, Goel NJ, Catalano MA, Sperry AE, Szeto J, Kurzan P, Lawrence KM, Desai, ND, Szeto WY, Holmes JH, Brown CR: Cardiac Valve Prosthesis Choice for Left-sided Infective Endocarditis in Medicare Patients. JTCVS Open. https://doi.org/10.1016/j.xjon.2025.09.050 November 2025.Sultan L, Venkatakrishna SSB, Anupindi S, Andronikou S, Acord M, Otero H, Holmes JH: ChatGPT-4-Driven Liver Ultrasound Radiomics Analysis: Advantages and Drawbacks Compared to Traditional Techniques. JMIR AI doi:10.2196/68144 2025.
Skarke C, Yang W, Sha D, Lahens NF, Isakova T, Unruh M, Deo R, Carmona-Powell E, Holmes JH, Ficarra E, Chen J, Jiang He, Rincon-Choles H, Shah V, Hsu CY, Anderson AH, Lash JP, Rahman M: A multi-center study to discern the diurnal variation of wearable device-based heart rate variability (HRV) in the Chronic Renal Insufficiency Cohort (CRIC) Study. medRxiv doi:10.1101/2025.04.30.25326177 2025.
Beidler E, Teel E, Schmitt AJ, Muccio G, Holmes JH, Bretzin AC: Anxiety-Related Concussion Perceptions of Parents of Youth Athletes. Journal of Athletic Training Dec 2024.
Moutchia J, McClelland RL, Al-Naamani N, Appleby, Holmes JH, Minhas J, Mazurek JA, Palevsky HI, Ventetuolo CE, Kawut SM: Pulmonary arterial hypertension treatment: an individual participant data network meta-analysis. European Heart Journal Page: ehae049, Feb 2024.
Getzen E, Tan AL, Brat G, Omenn GS, Strasser Z; Consortium for Clinical Characterization of COVID-19 by EHR (4CE) (Collaborative Group/Consortium); Long Q, Holmes JH, Mowery D: Leveraging informative missing data to learn about acute respiratory distress syndrome and mortality in long-term hospitalized COVID-19 patients throughout the years of the pandemic. AMIA Annu Symp Proc Page: 942-950, Jan 2024.
Minhas J, Moutchia J, Al-Naamani N, Mazurek JA, Holmes JH, Appleby D, Smith KA, Fritz JS, Pugliese SC, Palevsky HI, Kawut SM: Electrocardiographic Abnormalities and Their Association with Outcomes in Randomized Clinical Trials of Pulmonary Arterial Hypertension. Ann Am Thorac Soc Jan 2024.
Bretzin AC, Schmitt AJ, Teel E, Holmes JH, Wiebe DJ, Beidler E: Parent and Youth Athlete Perceptions of Concussion Injury: Establishing a Factor Structure. Arch Clin Neuropsychol Jan 2024.
Koch S, Holmes JH, Sacchi L: Unlocking the Potential of the Next Generation: Methods of Information in Medicine Student Paper Award 2024. Methods Inf Med 63(3-04): 63-65, 2024.
Dixon BE, Holmes JH: Special Section on Digital Health for Precision in Prevention: Notable Papers that Leverage Informatics Approaches to Support Precision Prevention Efforts in Health Systems. nternational Medical Informatics Association Yearbook of Medical Informatics 33(1): 70-72, 2024.
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