David J. Margolis, MD, Ph.D

faculty photo
Gerald R. Lazarus Professor
Department: Dermatology

Contact information
901 Blockley Hall
423 Guardian Drive
Department of Dermatology and Department of Biostatistics and Epidemiology
University of Pennsylvania
Philadelphia, PA 19104-4283
Office: 215-662-2590
Lab: 215 898 4938
Wesleyan University, 1981.
University of Chicago-Pritzker, 1985.
M.S.C.E. (Epidemiology)
University of Pennsylvania, 1998.
Ph.D. (Epidemiology)
University of Pennsylvania, 2000.
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Description of Research Expertise

epidemiology, clinical trials, pharmacoepidemiology, wound repair, chronic wounds

Description of Clinical Expertise

dermatology, chronic wounds

Selected Publications

Margolis DJ, Mitra N, Duke JL, Berna R, Margolis JD, Hoffstad O, Kim BS, Yan AC, Zaenglein AL, Chiesa Fuxench Z, Dinou A, Wasserman J, Tairis N, Mosbruger TL, Ferriola D, Damianos G, Kotsopoulou I, Monos DS.: Human Leukocyte Antigen Class-I Variation is Associated with Atopic Dermatitis: A Case-control Study. Hum Immunol. 82(8): 593-599, August 2021.

Margolis DJ, Mitra N, Kim BS, Duke JL, Berna RA, Hoffstad OJ, Wasserman JR, Ferriola DA, Mosbruger TL, Wubbenhorst BS, Nathanson KL, Monos DS.: HLA Class I Polymorphisms Influencing Both Peptide Binding and KIR Interactions Are Associated with Remission among Children with Atopic Dermatitis: A Longitudinal Study. J Immunol. 1(206 (9)): 2038-2044, May 2021.

Berna R, Mitra N, Lou C, Wan J, Hoffstad O, Wubbenhorst B, Nathanson KL, Margolis DJ.: TSLP and IL-7R Variants Are Associated with Persistent Atopic Dermatitis. J Invest Dermatol. 141(2): 446-450.e2, February 2021.

Wang F, Trier AM, Li F, Kim S, Chen Z, Chai JN, Mack MR, Morrison SA, Hamilton JD, Baek J, Yang TB, Ver Heul AM, Xu AZ, Xie Z, Dong X, Kubo M, Hu H, Hsieh CS, Dong X, Liu Q, Margolis DJ, Ardeleanu M, Miller MJ, Kim BS.: A Basophil-neuronal Axis Promotes Itch. Cell. 21(184 (2)): 422-440.e17, January 2021 Notes: PMC7878015.

Barbieri JS, Margolis DJ.: Optimizing the Trial Design for a Comparative Effectiveness Study of Spironolactone versus Oral Antibiotics for Women With Acne: A Delphi Consensus Panel. J Drugs Dermatol. Page: 1;19 (12):1238-1239. December 2020.

Margolis DJ, Mitra N, Monos DS.: Rheumatoid Arthritis Known HLA Associations are Unlikely To Be Associated With Atopic Dermatitis. J Rheumatol. October 2020.

Winters C, Kirsner RS, Margolis DJ, Lantis JC.: Cost Effectiveness of Fish Skin Grafts Versus Standard of Care on Wound Healing of Chronic Diabetic Foot Ulcers: A Retrospective Comparative Cohort Study. Wounds. 32(10): 283-290. October 2020.

Paller AS, Fölster-Holst R, Chen SC, Diepgen TL, Elmets C, Margolis DJ, Pollock BH: No Evidence of Increased Cancer Incidence in Children Using Topical Tacrolimus for Atopic Dermatitis. J Am Acad Dermatol 83(2): 375-381, Aug 2020.

Barbieri JS, Mitra N, Margolis DJ, Harper CC, Mostaghimi A, Abuabara K.: Influence of Contraception Class on Incidence and Severity of Acne Vulgaris. Obstet Gynecol. Page: 135(6):1306-1312. June 2020.

Thapa RK, Margolis DJ, Kiick KL, Sullivan MO. : Enhanced Wound Healing via Collagen-turnover-driven Transfer of PDGF-BB Gene in a Murine Wound Model. ACS Appl Bio Mater. 15(3(6)): 3500-3517, June 2020.

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Last updated: 12/16/2021
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