Jinbo Chen, Ph.D.
Department of Biostatistics, Epidemiology and Informatics
203 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
Beijing Normal University, P.R. China, 1992.
University of Washington, Seattle, WA, 1999.
University of Washington, Seattle, WA, 2002.
Description of Research ExpertiseDr. Jinbo Chen’s primary areas of research include the development of statistical methods for designing and analyzing two-phase epidemiologic studies, methodological and collaborative work in genetic association studies of complex diseases, and the development and evaluation of risk prediction models. Dr. Chen has published numerous methods papers on haplotype analysis using data from cohort, nested case-control, and matched case-control designs, methods on exploring gene-gene and gene-environment interactions, and efficient methods for screening SNP
genotypes. Her recent work has focused on design and analyses issues arising from studies of complex genetic and environmental effects on pregnancy-related and early-life disorders. Dr. Chen has been collaborating with researchers on dissecting genetic and environmental influences on the risk of biliary tract cancer, childhood leukemia, preterm birth, food allergy, and cardio-metabolic and cardiovascular diseases.
Selected PublicationsChen J, Chatterjee N: Haplotype-based association analysis in cohort and nested case-control studies. Biometrics 62(1): 28-35, 2006.
Chen J, Pee D, Ayyagari R, Graubard B, Schairer C, Byrne C, Benichou J, Gail, MH: Projecting absolute invasive breast cancer risk in white women with a model that includes mammographic density. Journal of the National Cancer Institute 98(17): 1215-1226, 2006.
Chen J, Peters U, Foster C, Chatterjee N: A haplotype-based test of association using data from cohort and nested case-control epidemiological studies. Human Heredity 58(1): 18-29, 2004.
Chen J, Breslow NE: Semiparametric efficient estimation for the auxiliary outcome problem with the conditional mean model. Canadian Journal of Statistics 32(4): 359-372, 2004.
Sakado LC, Gao YT, Chen BE, Chen J, Rosenberg P, Rashid A, Deng J, Shen MC, Wang BS, Han TQ, Zhang BH, Cohen-Webb H, Yeager M, Welsh R, Chanock S, Fraumeni JF, Hsing AW: Prostaglandin-endoperoxide synthase 2(PTGS2) gene polymorphisms and risk of biliary tract cancer and gallstones: A population-based study in Shanghai, China. Carcinogenesis 27(6): 1251-1256, 2006.
Engels EA, Chen J, Viscidi RP, Shah KV, Daniel RW, Chatterjee N, Klebanoff MA : Poliovirus vaccination during pregnancy, maternal seroconversion to Simian virus 40, and risk of childhood cancer. American Journal of Epidemiology 160(4): 306-316, 2004.
Baccarelli A, Hou L, Chen J, Lissowska J, El-Omar EM, Grillo P, Giacomini SM, Yaeger M, Bernig T, Zatonski W, Fraumeni JF Jr, Chanock SJ, Chow WH: Mannose-binding lectin-2 genetic variation and stomach cancer risk. International Journal of Cancer 119(8): 1970-1975, 2006.
Engels EA, Brock MV, Chen J, Gillison M, Hooker C, Moore RD: Elevated incidence of lung cancer among HIV-infected individuals. Journal of Clinical Oncology 24(9): 1383-1388, 2006.
Fossa SD, Chen J, Schonfeld S, McGlynn K, McMaster M, Gail MH, Travis LB: Risk of contralateral testicular cancer: a population-based study of 29,515 U.S. men. Journal of the National Cancer Institute 97(14): 1056-1066, 2005.
Engels EA, Chen J, Hartge P, Cerhan JR, Davis S, Severson RK, Cozen W, Viscidi RP: Antibody responses to simian virus 40 T antigen: a case-control study of non-Hodgkin’s lymphoma. Cancer Epidemiology, Biomarkers & Prevention 14(2): 521-524, 2005.