Daniel N Holena, MD MCSE

faculty photo
Associate Professor of Surgery at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia
Department: Surgery
Graduate Group Affiliations

Contact information
Division of Trauma, Surgical Critical Care & Emergency Surgery
Penn Presbyterian Medical Center
51 North 39th St., Suite 120
Philadelphia, PA 19104
Office: 215-662-7323
Fax: 215-243-3221
McGill University, Montreal , 1995.
State University of New York at Stony Brook , 2002.
University of Pennsylvania Center for Clinical Epidemiology and Biostatistics, 2011.
MSCE (Epidemiology)
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 2015.
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Description of Clinical Expertise

Dr. Daniel Holena is board certified in General Surgery and Surgical Critical Care. He received his General Surgery training at Cornell, and completed is fellowship in Trauma Surgery and Surgical Critical Care at the University of Pennsylvania. Dr. Holena specializes in the treatment of traumatic injury, emergency general surgery conditions, and surgical critical care. His research interests include outcomes after emergency general surgery and triage biomarkers in acute trauma.

Description of Research Expertise

Dr. Holena's research interests encompass the study of quality of care after injury. He has a specific interest in the methodology used for risk-adjusting trauma morbidity, mortality, and failure to rescue.

Selected Publications

Hatchimonji J, Passman J, Kaufman E, Sharoky C, Ma L, Scantling D, Xiong A, Holena D: Enterocutaneous Fistula After Emergency General Surgery: Mortality, Readmission, and Financial Burden. Journal of Trauma March 2020.

Dumas RP, Jafari D, Moore SA, Ruffolo L, Holena DN, Seamon MJ: Emergency Department Versus Operating Suite Intubation in Operative Trauma Patients: Does Location Matter? World J Surg 44(3): 780-787, Mar. 2020 Notes: doi: 10.1007/s00268-019-05296-1.

Laytin AD, Clarke D, Gerdin Wärnberg M, Kong VY, Bruce JL, Laing G, Holena DN, Juillard CJ: The Search for a Simple Injury Score to Reliably Discriminate the Risk of In-Hospital Mortality in South Africa Surgery Feb. 2020 Notes: doi: 10.1016/j.surg.2020.01.009.

Hatchimonji J, Kaufman E, Dumas R, Scantling D, Stoecker J, Holena D: Challenging Dogma: Does a GCS of 8 require intubation? Annual Academic Surgical Congress, Orlando FL Feb. 2020.

Scantling D, Holena D, Yang W, Christie J, Xiong A, Hatchimonji J, Reilly P : Cardiac Complications and Failure to Rescue After Injury in a Mature State Trauma System: Towards Identifying Opportunities for Improvement Injury Injury Feb. 2020 Notes: https://doi.org/10.1016/j.injury.2020.02.003.

Faust HE, Reilly JP, Anderson BJ, Ittner CAG, Forker CM, Zhang P, Weaver BA, Holena DN, Lanken PN, Christie JD, Meyer NJ, Mangalmurti NS, Shashaty MGS: Plasma Mitochondrial DNA Levels Are Associated With ARDS in Trauma and Sepsis Patients Chest 157(1): 67-76, Jan. 2020 Notes: doi: 10.1016/j.chest.2019.09.028.

Dumas R, Moore S, Jafari D, Holena D, Ruffolo L, Seamon M: Emergency Department versus Operating Suite Intubation in Operative Trauma Patients: Does Location Matter? World Journal of Surgery 44: 780-787, 2020.

Faust H , Holena DN: Plasma Mitochondrial DNA Levels are Associated with Acute Respiratory Distress Syndrome in Trauma and Sepsis Patients Thorax 2020.

Hatchimonji J, Kaufman E, Sharoky C, Ma L, Garcia A, Holena D: Failure to Rescue in Surgical Patients: A Review for Acute Care Surgeons. Journal of Trauma 2019

Mullens CL, Seamon MJ, Shiroff A, Cannon JW, Kaplan LJ, Pascual JL, Holena DN, Martin ND: A Statewide Assessment of Rib Fixation Patterns Reveals Missed Opportunities Journal of Surgical Research 244: 205-211, Dec. 2019 Notes: doi: 10.1016/j.jss.2019.06.048.

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Last updated: 08/17/2020
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