Faculty

Russell Takeshi Shinohara, Ph.D.

Professor of Biostatistics and Epidemiology

Department: Biostatistics and Epidemiology

Graduate Group Affiliations

Contact information

Center for Clinical Epidemiology and Biostatistics
Department of Biostatistics, Epidemiology and Informatics
Perelman School of Medicine
University of Pennsylvania
217 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104-6021

Office: 215-746-1090
Fax: 215-573-1050

Email:
rshi@pennmedicine.upenn.edu

Education:
Honors BSc (Probability and Statistics)
McGill University, 2006.
MSc (Mathematics and Statistics)
McGill University, 2007.
PhD (Biostatistics)
The Johns Hopkins University, 2012.

Links
Penn Statistical Imaging and Visualization Endeavor

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Puvvula J, Hwang WT, McCandless L, Xie C, Braun JM, Vuong AM, Oulhote Y, Schisterman EF, Shinohara RT, Booij L, Bouchard MF, Linn K, Borghese MM, Seguin JR, Zidek A, Till C, Fraser W, Yolton K, Cecil KM, Ashley-Martin J, Arbuckle TE, Lanphear B, Chen A: Gestational exposure to environmental chemical mixtures and cognitive abilities in children: A pooled analysis of two North American birth cohorts Environmental International 196: 109298, Feb 2025 Notes: doi: 10.1016/j.envint.2025.109298. Epub 2025 Jan 29.

Ripart M, Spitzer H, Williams LZJ, Walger L, Chen A, Napolitano A, Rossi- Espagnet C, Foldes ST, Hu W, Mo J, Likeman M, Rüber T, Caligiuri ME, Gambardella A, Guttler C, Tietze A, Lenge M, Guerrini R, Cohen NT, Wang I, Kloster A, Pinborg LH, Hamandi K, Jackson G, Tortora D, Tisdall M, Conde-Blanco E, Pariente JC, Perez-Enriquez C, Gonzalez-Ortiz S, Mullatti N, Vecchiato K, Liu Y, Kalviainen R, Sokol D, Shetty J, Sinclair B, Vivash L, Willard A, Winston GP, Yasuda C, Cendes F, Shinohara RT, Duncan JS, Cross JH, Baldeweg T, Robinson EC, Iglesias JE, Adler S, Wagstyl K; MELD FCD writing group; Fawaz A, De Benedictis A, De Palma L, Zhang K, Labate A, Barba C, You X, Gaillard WD, Tang Y, Wang S, Davies S, Semmelroch M, Severino M, Striano P, Chari A, D'Arco F, Mankad K, Bargallo N, Pascual-Diaz S, Delgado-Martinez I, O'Muircheartaigh J, Abela E, Kandasamy J, McLellan A, Desmond P, Lui E, O'Brien TJ, Whitaker K: Detection of Epileptogenic Focal Cortical Dysplasia Using Graph Neural Networks: A MELD Study. JAMA Neurology Page: e245406, Feb 2025 Notes: doi: 10.1001/jamaneurol.2024.5406. Epub ahead of print.

Martin ML, Cao Q, Luskin E, Renner B, Daboul L, O'Donnell CM, Rodrigues P, Derbyshire J, Azevedo CJ, Bar-Or A, Caverzasi E, Calabresi P, Cree BAC, Freeman L, Henry RG, Longbrake EE, Oh J, Papinutto N, Pelletier D, Prchkovska V, Ramos M, Samudralwar RD, Schindler MK, Sotirchos ES, Sicotte NL, Solomon AJ, Reich DS, Ontaneda D, Shinohara RT, Sati P: Reliability of Central Vein Sign Imaging With 3T FLAIR* in a Multicenter Study. Journal of Neuroimaging 35(1): e70011, Jan-Feb 2025.

Pecsok MK, Robinson H, Atkins A, Calkins ME, Elliott MA, Mordy A, Stifelman J, Gur RC, Moberg PJ, Nanga RPR, Ruparel K, Shinohara RT, Wolk DA, Reddy R, Roalf DR: Mapping hippocampal glutamate in healthy aging with in vivo glutamate-weighted CEST (GluCEST) imaging. Frontiers in Aging Neuroscience 16: 1535158, Jan 2025.

Solomon AJ, Weinstein S, Shinohara RT, Aoun SM, Schmidt H, Solari A: Diagnostic Delay and Misdiagnosis of Symptoms Reported by Patients with Multiple Sclerosis Participating in a Research Registry. Multiple Sclerosis Journal – Experimental, Translational and Clinical In press 2025.

Sydnor VJ, Bagautdinova J, Larsen B, Arcaro MJ, Barch DM, Bassett DS, Alexander-Bloch AF, Cook PA, Covitz S, Franco AR, Gur RE, Gur RC, Mackey AP, Mehta K, Meisler SL, Milham MP, Moore TM, Müller EJ, Roalf DR, Salo T, Schubiner G, Seidlitz J, Shinohara RT, Shine JM, Yeh FC, Matthew Cieslak M, Satterthwaite TD: Human thalamocortical structural connectivity develops in line with a hierarchical axis of cortical plasticity. Nature Neuroscience In press 2025.

Gardner M, Shinohara RT, Bethlehem RAI, Romero-Garcia R, Warrier V, Dorfschmidt L, Lifespan Brain Chart Consortium, Shanmugan S, Seidlitz J, Alexander-Bloch A, Chen A: ComBatLS: A location- and scale-preserving method for multi-site image harmonization. Human Brain Mapping In press 2025.

Keller AS, Sun KY, Francisco A, Robinson H, Beydler E, Bassett DS, Cieslak M, Cui Z, Davatzikos C, FanY, Gardner M, Kishton R, Kornfield SL, Larsen B, Li H, Linder I, Pines A, Pritschet L, Raznahan A, Roalf DR, Seidlitz J, Shafiei G, Shinohara RT, Lauren K. White LK, Wolf DH, Alexander-Bloch A, Satterthwaite TD, Shanmugan S: Reproducible Sex Differences in Personalized Functional Network Topography in Youth. British Journal of Psychiatry In press 2025.

Roalf, DR, Atkins, A, Czernuszenko, A, Pecsok MK, McDonald-McGinn, DM, Schmitt JE, Roeske MJ, Hopkins S, Freedman P, Alexander-Bloch A, Schabdach J, Jung B, Crowley TB, Gallagher RS, McGinn DE, Moberg PJ, Ruparel K, Shinohara RT, Turetsky BI, White L, Zackai EH, Gur RC, Gur RE: Presence, severity, and functional associations of incomplete hippocampal inversion in 22q11.2 deletion syndrome. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging In press 2025.

Thompson EW, Dong NJ, Kim JS, Bhattaru A, Vu P, Hu F, Shinohara RT, Swago S, Donnelly E, Zhang X, Loth A, Vuthuri L, Lanzilotta K, Whitehead KK, Duda J, Gee J, Almasy L, Goldmuntz E, Fogel MA, Witschey WR: Cardiovascular Magnetic Resonance Imaging Traits Associated with Adverse Right Ventricular Remodeling in Repaired Tetralogy of Fallot. J Cardiovasc Magn Reson In press 2025.