Faculty

Haochang Shou, Ph.D.

Associate Professor of Biostatistics in Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania

Department: Biostatistics and Epidemiology

Graduate Group Affiliations

Graduate Group in Epidemiology and Biostatistics

Contact information

Department of Biostatistics, Epidemiology and Informatics
University of Pennsylvania School of Medicine
219 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104

Office: 215-573-6534

Email:
hshou@pennmedicine.upenn.edu

Education:
B.Sc. (Statistics)
Peking University, China, 2009.
Ph.D. (Biostatistics)
Johns Hopkins Bloomberg School of Public Health, 2014.

Links
The Penn Statistics in Imaging and Visualization Center (PennSIVE)

Permanent link

> Perelman School of Medicine > Faculty > Details

Description of Research Expertise

Dr. Shou’s methodological research mainly focuses on functional data analysis with complex structures. She is particularly interested in novel statistical modeling and estimation techniques for multimodal functional and longitudinal measurements, including neuroimaging and human activity data. Her collaborations span brain disorder studies, mental health, and biomarker evaluation for chronic kidney disease.

Selected Publications

Zhang, J; Guo, W; Carpenter, JS; Leroux, A; Merikangas, KS; Martin, NG; Hickie, IB; Shou, H; Li, H.: Empirical Likelihood Inference of Variance Components in Linear Mixed-Effects Models. Statistical Sinica 2023, accepted Notes: 10.5705/ss.202022.0336.

Laughlin, AI; Cao, Q; Bryson, R; Haughey, V; Abdul-Salaam, R; Gonzenbach, V; Rudraraju, M; Eydman, I; Tweed, CM; Fala, GJ; Patel, K; Fox, KR; Hanson, CW; Bekelman, JE; Shou, H.: Detection of Medication Taking using Wrist-worn Commercially Available Wearable Device. JCO Clinical Cancer Informatics 2023, accepted.

Zhang, J; Basner, M; Jones, CW; Dinges, DF; Shou, H; Li, H : Mediation Analysis with Random Distribution as Mediator with an Application to iCOMPARE Trial. Stat Biosci. Aug 2023 Notes: https://doi-org.proxy.library.upenn.edu/10.1007/s12561-023-09383-9.

Dubin RF, Deo R, Ren Y, Lee H, Shou H, Feldman H, Kimmel P, Waikar SS, Rhee EP, Tin A, Chen J, Coresh J, Go AS, Kelly T, Rao PS, Chen TK, Segal MR, Ganz P.: Analytical and Biological Variability of a Commercial Modified Aptamer Assay in Plasma Samples of Patients with Chronic Kidney Disease. J Appl Lab Med. 8(3): 491-503, May 2023 Notes: doi: 10.1093/jalm/jfac145.

Hwang G, Wen J, Sotardi S, Brodkin ES, Chand GB, Dwyer DB, Erus G, Doshi J, Singhal P, Srinivasan D, Varol E, Sotiras A, Dazzan P, Kahn RS, Schnack HG, Zanetti MV, Meisenzahl E, Busatto GF, Crespo-Facorro B, Pantelis C, Wood SJ, Zhuo C, Shinohara RT, Shou H, Fan Y, Di Martino A, Koutsouleris N, Gur RE, Gur RC, Satterthwaite TD, Wolf DH, Davatzikos C.: Assessment of Neuroanatomical Endophenotypes of Autism Spectrum Disorder and Association With Characteristics of Individuals With Schizophrenia and the General Population. JAMA Psychiatry 80(4): 498-507, May 2023 Notes: doi: 10.1001/jamapsychiatry.2023.0409.

Dwyer DB, Chand GB, Pigoni A, Khuntia A, Wen J, Antoniades M, Hwang G, Erus G, Doshi J, Srinivasan D, Varol E, Kahn RS, Schnack HG, Meisenzahl E, Wood SJ, Zhuo C, Sotiras A, Shinohara RT, Shou H, Fan Y, Schaulfelberger M, Rosa P, Lalousis PA, Upthegrove R, Kaczkurkin AN, Moore TM, Nelson B, Gur RE, Gur RC, Ritchie MD, Satterthwaite TD, Murray RM, Di Forti M, Ciufolini S, Zanetti MV, Wolf DH, Pantelis C, Crespo-Facorro B, Busatto GF, Davatzikos C, Koutsouleris N, Dazzan P.: Psychosis brain subtypes validated in first-episode cohorts and related to illness remission: results from the PHENOM consortium. Mol Psychiatry. May 2023 Notes: doi: 10.1038/s41380-023-02069-0. [Epub ahead of print]

Basner M, Smith MG, Jones CW, Ecker AJ, Howard K, Schneller V, Cordoza M, Kaizi-Lutu M, Park-Chavar S, Stahn AC, Dinges DF, Shou H, Mitchell JA, Bhatnagar A, Smith T, Smith AE, Stopforth CK, Yeager R, Keith RJ.: Associations of bedroom PM2.5, CO2, temperature, humidity, and noise with sleep: An observational actigraphy study. Sleep Health April 2023 Notes: doi: 10.1016/j.sleh.2023.02.010. [Epub ahead of print]

Deo R, Dubin RF, Ren Y, Murthy AC, Wang J, Zheng H, Zheng Z, Feldman H, Shou H, Coresh J, Grams M, Surapaneni AL, Bhat Z, Cohen JB, Rahman M, He J, Saraf SL, Go AS, Kimmel PL, Vasan RS, Segal MR, Li H, Ganz P.: Proteomic cardiovascular risk assessment in chronic kidney disease. Eur Heart J. April 2023 Notes: doi: 10.1093/eurheartj/ehad115. [Epub ahead of print]

Wyss P, Ginsbourger D, Shou H, Davatzikos C, Klöppel S, Abdulkadir A. : Adaptive data-driven selection of sequences of biological and cognitive markers in pre-clinical diagnosis of dementia. Sci Rep. 13(1): 5406. April 2023 Notes: doi: 10.1038/s41598-023-32867-z.

Fu CHY, Erus G, Fan Y, Antoniades M, Arnone D, Arnott SR, Chen T, Choi KS, Fatt CC, Frey BN, Frokjaer VG, Ganz M, Garcia J, Godlewska BR, Hassel S, Ho K, McIntosh AM, Qin K, Rotzinger S, Sacchet MD, Savitz J, Shou H, Singh A, Stolicyn A, Strigo I, Strother SC, Tosun D, Victor TA, Wei D, Wise T, Woodham RD, Zahn R, Anderson IM, Deakin JFW, Dunlop BW, Elliott R, Gong Q, Gotlib IH, Harmer CJ, Kennedy SH, Knudsen GM, Mayberg HS, Paulus MP, Qiu J, Trivedi MH, Whalley HC, Yan CG, Young AH, Davatzikos C: AI-based Dimensional Neuroimaging System for Characterizing Heterogeneity in Brain Structure and Function in Major Depressive Disorder: COORDINATE-MDD Consortium Design and Rationale. BMC Psychiatry 23(59), Jan 2023 Notes: doi.org/10.1186/s12888-022-04509-7.