Haochang Shou, Ph.D.

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Assistant Professor of Biostatistics in Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania
Department: Biostatistics and Epidemiology

Contact information
Department of Biostatistics, Epidemiology and Informatics
University of Pennsylvania School of Medicine
219 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
Office: 215-573-6534
B.Sc. (Statistics)
Peking University, China, 2009.
Ph.D. (Biostatistics)
Johns Hopkins Bloomberg School of Public Health, 2014.
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Description of Research Expertise

Dr. Shou’s methodological research mainly focuses on functional data analysis with complex structures. She is particularly interested in novel statistical modeling and estimation techniques for multimodal functional and longitudinal measurements, including neuroimaging and human activity data. Her collaborations span brain disorder studies, mental health, and biomarker evaluation for chronic kidney disease.

Selected Publications

Zhang, J; Merikangas, KR; Li, H*; Shou, H*: Two-sample Tests for Multivariate Repeated Measurements of Histogram Objects with Applications to Wearable Device Data. Annals of Applied Statistics 16(4): 2396-2416, Dec 2022 Notes: DOI: 10.1214/21-AOAS1596.

Wen, D; Zheng, Z; Surapaneni, A; Yu, B; Zhou, L; Zhou, W; Xie, D; Shou, H; Avila-Pacheco, J; Kalim, S; He, J; Hsu, CY; Parsa, A; Rao, P; Sondheimer, J; Townsend, R; Waikar, SS; Rebholz, CM; Denburg, MR; Kimmel, PL; Vasan, RS; Clish, CB; Coresh, J; Feldman, HI; Grams, ME; Rhee, EP: Metabolite Profiling of CKD Progression in the Chronic Renal Insufficiency Cohort (CRIC) Study. JCI Insight Sep 2022.

Chand, G; Singhal, P; Dwyer, D; Wen, J; Erus, G; Doshi, J; Srinivasan, D; Mamourian, E; Varol, E; Sotiras, A; Hwang, G; Dazzan, P; Kahn, R; Schnack, H; Zanetti, M; Meisenzahl, E; Busatto, G; Crespo-Facorro, B; Pantelis, C; Wood, S; Zhuo, C; Shinohara, R; Shou, H; Fan, Y; Koutsouleris, N; Kaczkurkin, A; Moore, T; Verma, A, Calkins, M; Gur, RE; Gur, RC; Ritchie, M; Satterthwaite, T; Wolf, D; Davatzikos, C: Schizophrenia Imaging Signatures and their Associations With Cognition, Psychopathology, and Genetics in the General Population. Am J Psychiatry 179(9): 650-660, Sep 2022 Notes: doi: 10.1176/appi.ajp.21070686. Online ahead of print.

Bashyam, V; Doshi, J; Erus, G; Srinivasan, D; Abdulkadir, A; Singh, A; Habes, M; Fan, Y; Masters, C; Maruff, P; Zhuo, C; Völzke, H; Johnson, S; Fripp, J; Koutsouleris, N; Satterthwaite, T; Wolf, D; Gur, RE; Gur, RC; Morris, J; Albert, M; Grabe, H; Resnick, S; Bryan, N; Wittfeld, K; Bülow, R; Wolk, D; Shou, H; Nasrallah, I; Davatzikos, C: Deep Generative Medical Image Harmonization for Improving Cross-Site Generalization in Deep Learning Predictors. Journal of Magnetic Resonance Imaging 55(3): 908-916, Sep 2022 Notes: doi:10.1002/jmri.27908. Epub 2021 Sep 25.

Chu, B; O’Connor, DM; Wan, MT; Barnett, I; Shou, H; Judson, MA; Rosenbach, M: Quality of Life and Physical Activity in 629 Individuals with Sarcoidosis: Prospective, Cross-sectional Study using Smartphones (Sarcoidosis App). JMIR mHealth and uHealth 10(8): e38331, Aug 2022.

Tu, D; Basner, M; Smith, MG; Williams, ES; Ryder, VE; Romoser, AA; Ecker, A; Aeschbach, D; Stahn, A; Jones, CW; Howard, K; Kaizi-lutu, M; Dinges, DF; Shou, H: Dynamic Ensemble Prediction of Cognitive Performance in Spaceflight. Scientific Reports 12(1): 11032, Jun 2022 Notes: doi: 10.1038/s41598-022-14456-8.

Hwang, G; Ahmed, A; Erus, G; Habes, M; Pomponio, R; Shou, H; Doshi, J; Mamourian, E; Rashid, T; Bilgel, M; Fan, Y; Sotiras, A; Srinivasan, D; Morris, JC; Albert, MS; Bryan, NR; Resnick, SM; Nasrallah, IM; Davatzikos, C; Wolk, DA; from the iSTAGING consortium; for the ADNI: Disentangling Alzheimer’s Disease Neurodegeneration from Typical Brain Ageing using Machine Learning. Brain Communications 4(3): fcac117, May 2022 Notes: https://doi.org/10.1093/braincomms/fcac117; online ahead of print.

Wen, J; Fu, C; Tosun, D; Veturi, Y; Yang, Z; Abdulkadir, A; Mamourian, E; Srinivasan, D; Skampardoni, I; Singh, A; Nawani, H; Bao, J; Erus, G; Shou, H; Habes, M; Doshi, J; Varol, E; Mackin, R; Sotiras, A; Fan, Y; Saykin, A; Sheline, Y; Shen, L; Ritchie, M; Wolk, D; Albert, M; Resnick, S; Davatzikos, C; iSTAGING consortium; ADNI; BIOCARD; and BLSA: Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression. JAMA Psychiatry 79(5): 464-474, May 2022 Notes: doi:10.1001/jamapsychiatry.2022.0020. Epub ahead of print.

Minhas, J; Shou, H; Hershman, S; Zamanian, R; Ventetuolo, CE; Bull, T; Hemnes, A; Chakinala, M; Mathai, S; Al-Naamani, N; Ellenberg, S; Matura, L; Kawut, S; Shcherbina, A: Physical Activity and Its Association with Traditional Outcome Measures in Pulmonary Arterial Hypertension. Ann Am Thorac Soc 19(4): 572-582, Apr 2022 Notes: doi: 10.1513/AnnalsATS.202105-560OC.

Chen, A; Srinivasan, D; Pomponio, R; Fan, Y; Nasrallah, I; Resnick, S; Beason-Held, L; Davatzikos, C; Satterthwaite, T; Bassett, D; Shinohara, R; Shou, H: Harmonizing Functional Connectivity Reduces Scanner Effects in Community Detection. NeuroImage Apr 2022 Notes: doi:10.1016/j.neuroimage.2022.119198. Epub ahead of print.

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Last updated: 11/22/2022
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