Haochang Shou, Ph.D.

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Assistant Professor of Biostatistics in Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania
Department: Biostatistics and Epidemiology
Graduate Group Affiliations

Contact information
Department of Biostatistics, Epidemiology and Informatics
University of Pennsylvania School of Medicine
219 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
Office: 215-573-6534
B.Sc. (Statistics)
Peking University, China, 2009.
Ph.D. (Biostatistics)
Johns Hopkins Bloomberg School of Public Health, 2014.
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Description of Research Expertise

Dr. Shou’s methodological research mainly focuses on functional data analysis with complex structures. She is particularly interested in novel statistical modeling and estimation techniques for multimodal functional and longitudinal measurements, including neuroimaging and human activity data. Her collaborations span brain disorder studies, mental health, and biomarker evaluation for chronic kidney disease.

Selected Publications

Bashyam, VM, Doshi, J, Erus, G, Srinivasan, D, Abdulkadir, A, Singh, A, Habes, M, Fan, Y, Masters, CL, Maruff, P, Zhuo, C, Völzke, H, Johnson, SC, Fripp, J, Koutsouleris, N, Satterthwaite, TD, Wolf, DH, Gur, RE, Gur, RC, Morris, JC, Albert, MS, Grabe, HJ, Resnick, SM, Bryan, NR, Wittfeld, K, Bülow, R, Wolk, DA, Shou, H, Nasrallah, IM, Davatzikos, C: Deep Generative Medical Image Harmonization for Improving Cross-Site Generalization in Deep Learning Predictors. Journal of Magnetic Resonance Imaging Sep 2021.

Butler, ER; Chen, A; Ramadan, R; Le, T.T; Ruparel, K; Moore, TM; Satterthwaite, TD; Zhang, F; Shou, H; Gur, RC; Nichols, TE and Shinohara, RT: Statistical Pitfalls in Brain Age Analyses. Human Brain Mapping 42(13): 4092-4101, Sep 2021.

Song, J; Pavlou, A; Burke, M; Shou, H; Atsina, K; Xiao, J; Loevner, L; Mankoff, D; Fan, Z; Kasner, S: Imaging Endpoints of Intracranial Atherosclerosis using Vessel Wall MR Imaging: A Systematic Review. Neuroradiology 63(6): 847-856, Jun 2021 Notes: doi: 10.1007/s00234-020-02575-w. Online ahead of print.

Clasen, S; Shou, H; Freedman, G; Plastaras, J; Taunk, N; Teo, B; Smith, A; Demissei, B; Ky, B : Early Cardiac Effects of Contemporary Radiation Therapy in Patients With Breast Cancer. International Journal of Radiation Oncology, Biology, Physics 109(5): 1301-1310, Apr 2021 Notes: doi: 10.1016/j.ijrobp.2020.12.008. Epub 2020 Dec 17.

Bashyam, V; Shou, H; Davatzikos, C: Reply: From ‘loose fitting’ to High-performance, Uncertainty-aware Brain-age Modelling. Brain 144(144): e32, Mar 2021 Notes: https://doi.org/10.1093/brain/awaa455.

Hu, E; Coresh, J; Anderson, C; Appel, L; Grams, M; Crews, D; Mills, K; He, J; Scialla, J; Rahman, M; Navaneethan, S; Lash, J; Ricardo, A; Feldman, H; Weir, M; Shou, H; Rebholz, C; CRIC Study Investigators : Adherence to Healthy Dietary Patterns and Risk of CKD Progression and All-Cause Mortality: Findings from the CRIC Study. Am J Kidney Dis 77(2): 235-244, Feb 2021 Notes: doi: 10.1053/j.ajkd.2020.04.019. Epub 2020 Aug 5.

Difrancesco, S; Riese, H; Merikangas, K; Shou, H; Zipunnikov, V; Antypa, N; van Hemert, A; Schoevers, R; Penninx, B; Lamers, F: Sociodemographic, Health and Lifestyle, Sampling, and Mental Health Determinants of 24-Hour Motor Activity Patterns: Observational Study. Journal of Medical Internet Research 23(2): e20700, Feb 2021 Notes: doi: 10.2196/20700.

MacLean, M; Jehangir, Q; Vujkovic, M; Ko, Y; Litt, H; Borthakur, A; Sagreiya, H; Rosen, M; Mankoff, D; Schnall, M; Shou, H; Chirinos, J; Damrauer, S; Torigian, D; Carr, R; Rader, D; Witschey, W : Quantification of Abdominal Fat from Computed Tomography using Deep Learning and its Association with Electronic Health Records in an Academic Biobank. Journal of the American Medical Informatics Association Page: ocaa342, Feb 2021 Notes: doi: 10.1093/jamia/ocaa342. Online ahead of print.

Schrauben, S; Shou, H; Zhang, X; Hyre, A; Anderson, A; Bonventre, J; Chen, J; Coca, S; Furth, S; Greenberg, J; Gutierrez, O; Ix, J; Lash, J; Parikh, C; Rebholz, C; Sabbisetti, V; Sarnak, M; Shlipak, M; Waikar, S; Kimmel, P; Vasan, R; Feldman, H; Schelling, J; CKD Biomarkers Consortium and the Chronic Renal Insufficiency Cohort (CRIC) Study Investigators: Association of Multiple Plasma Biomarker Concentrations with Progression of Prevalent Diabetic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study. Journal of the American Society of Nephrology: JASN 32(1): 115-126, Jan 2021 Notes: doi: 10.1681/ASN.2020040487. Epub 2020 Oct 29.

Habes, M; Pomponio, R; Shou, H; Doshi, J; Mamourian, E; Erus, G; Nasrallah, I; Launer, L; Rashid, T; Bilgel, M; Fan, Y; Toledo, J; Yaffe, K; Sotiras, A; Srinivasan, D; Espeland, M; Masters, C; Maruff, P; Fripp, J; Volzk, H; Johnson, S; Morris, J; Albert, M; Miller, M; Bryan, R; Grabe, H; Resnick, S; Wolk, D; Davatzikos, C; iSTAGING consortium, the Preclinical AD consortium, the ADNI, and the CARDIA studies: The Brain Chart of Aging: Machine-learning Analytics Reveals Links between Brain Aging, White Matter Disease, Amyloid Burden, and Cognition in the iSTAGING Consortium of 10,216 Harmonized MR Scans. Alzheimer's & Dementia 17(1): 89-102, Jan 2021 Notes: doi: 10.1002/alz.12178. Epub 2020 Sep 13.

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Last updated: 12/02/2021
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