Rebecca A Hubbard, Ph.D.

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Professor of Biostatistics in Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania
Department: Biostatistics and Epidemiology

Contact information
Department of Biostatistics, Epidemiology & Informatics
University of Pennsylvania School of Medicine
604 Blockley Hall
423 Guardian Drive
Philadelphia, PA 19104
Office: 215-898-3311
Fax: 215-573-4865
B.S. (Ecology & Evolution, summa cum laude)
University of Pittsburgh, Pittsburgh, PA, 1999.
M.Sc. (Epidemiology)
University of Edinburgh, Edinburgh, UK, 2001.
M.Sc. (Applied Statistics, with honors)
Oxford University, Oxford, UK, 2002.
Ph.D. (Biostatistics)
University of Washington, Seattle, WA , 2007.
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Description of Research Expertise

Dr. Hubbard's research focuses on development and application of statistical methodology for studies using observational data from community medical practice. This work encompasses evaluation of screening and diagnostic test performance, methods for comparative effectiveness studies, and health services research. A wealth of data on healthcare utilization, performance, and outcomes are available from electronic medical records. However, the complex observation scheme giving rise to these data necessitates careful study design and analysis to ensure that inference is valid. Dr. Hubbard’s methodological research emphasizes development of statistical tools for such inference and has been applied to studies of cancer screening, aging and dementia, pharmacoepidemiology, women’s health, and behavioral health.

Selected Publications

Schinasi LH, Kenyon CC, Yen Y-T, Moore K, Melly S, Hubbard RA, Maltenfort M, Forrest CB, Diez Roux AV, De Roost AJ: Associations between high ambient temperatures and asthma exacerbations among children in Philadelphia, PA: A time series analysis. Occupational and Environmental Medicine 79(5): 326-332, May 2022.

Ellis DE, Hubbard RA, Willis AW, Zuppa AF, Zaoutis TE, Hennessy S: Comparing LASSO and random forest models for predicting neurological dysfunction among fluoroquinolone users. Pharmacoepidemiology & Drug Safety 31(4): 393-403, April 2022.

Parikh RB, Takvorian SU, Vader D, Wileyto EP, Clark AS, Lee DJ, Goyal G, Rocque GB, Dotan E, Geynisman DM, Phull P, Spiess PE, Kim RY, Davidoff AJ, Gross CP, Miksad RA, Calip GS, Ferrell W, Shulman LN, *Mamtani R, *Hubbard RA: Impact of the COVID-19 pandemic on treatment patterns for patients with metastatic solid cancer in the United States. JNCI 29(5): 918-927, April 2022 Notes: *Equal contribution.

Ho T-QH, Bissell MCS, Kerlikowske K, Hubbard RA, Sprague BL, Lee CI, Tice JA, Rauscher GH, Tosteson ANA, Miglioretti DL for the Breast Cancer Surveillance Consortium: Cumulative probability of false positive results after 10 years of screening with digital breast tomosynthesis vs. digital mammography. JAMA Network Open 5(3): e222440, March 2022.

Sobrin L, Yu Y, Han S, Susarla G, Kempen JH, Hubbard RA, VanderBeek BL: Angiotensin converting enzyme-inhibitors and incidence of non-infectious uveitis in a large healthcare claims database. Ophthalmic Epidemiology 29(1): 25-30, January 2022.

Aysola J, Rewley J, Xu C, Schapira M, Hubbard RA: Primary care patient social networks and tobacco use: An observational study. Journal of Primary Care and Community Health 13: 1-10, January 2022.

Harton J, Segal B, Mamtani R, *Mitra N, *Hubbard RA: Combining real-world and randomized control trial data using data-adaptive weighting via the on-trial score. Statistics in Biopharmaceutical Research In press, 2022 Notes: *Equal contribution.

Harton J, *Mitra N, *Hubbard RA: Informative presence bias in analyses of electronic health records-derived data: A cautionary note. Journal of the American Medical Informatics Association In press, 2022 Notes: *Equal contribution.

Ginestra JC, Kohn R, Hubbard RA, Crane-Droesch A, Halpern SD, Prasad Kerlin M, Weissman GE: Association of unit census with delays in antimicrobial initiation among ward patients with hospital-acquired sepsis. Annals of the American Thoracic Society In press, 2022.

Nimgaonkar V, Hubbard RA, Carpenter EL, Mamtani R: Biomarker testing, treatment uptake, and outcomes for the first oral targeted therapy in urothelial cancer. JAMA Oncology In press, 2022.

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Last updated: 06/09/2022
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