Faculty
Kandace L Gollomp, MD
Assistant Professor of Pediatrics (Hematology)
Department: Pediatrics
Graduate Group Affiliations
Contact information
Children's Hospital of Philadelphia
Abramson Research Center, Office 316E
3615 Civic Center Blvd
Philadelphia, PA 19147
Abramson Research Center, Office 316E
3615 Civic Center Blvd
Philadelphia, PA 19147
Office: 2154592468
Publications
Education:
BA (English)
Yale University, 2004.
MD (Medicine)
University of Pennsylvania School of Medicine, 2010.
Permanent linkBA (English)
Yale University, 2004.
MD (Medicine)
University of Pennsylvania School of Medicine, 2010.
Description of Clinical Expertise
Pediatric benign hematologyDescription of Research Expertise
My research focuses on therapies that modify neutrophil extracellular traps (NETs) to improve their ability to capture pathogens including viruses and bacteria, while decreasing their ability to induce harm to host tissue. Such treatments may improve outcomes in conditions such as sepsis, sickle cell disease, heparin-induced thrombocytopenia, and anti-phospholipid antibody syndromeSelected Publications
Amrita Sarkar, Conroy Field, Khalil Bdeir, Santosh Yadav Kandace Gollomp, Keith McCrae, Thomas Ortel, Jason Knight, Jérôme Rollin, Yves Gruel, Gow Arepally,Lubica Rauova, Mortimer Poncz: Antiphospholipid syndrome (APS) is the newest member of the PF4 immunothrombotic family: Mechanistic and therapeutic insights. ASH 2025 Annual Meeting, Orlando Florida (abs25-1773), December 2025 Notes: https://meetings-api.hematology.org/api/abstract/vmpreview/290418.Andrew Fleischman, David Light, Kandace Gollomp, Conroy Field, Benita Balogun, Tonimarie Ruggiero, Mariana Macias, Szirina Ismail, Sophia Sun, Clark Brown, Martin Safo, Osheiza Abdulmalik : Direct hemoglobin S polymerization inhibitor MCP435 completely halts ongoing disease pathophysiology in transgenic sickle cell disease mice. American Society of Hematology Annual Meeting 2025, Orlando Florida (Abs25-11990), December 2025 Notes: Poster presentation.
Magdalene Ford, Zhuangzhuang Geng, Susanna Ostrowski, Anna Prykhodko, Arden McAllister, Andrea Roe, Kandace Gollomp : Cell-free DNA (cfDNA) and plasma proteomics reveal inflammatory heterogeneity in vasoocclusive crises in sickle cell disease (SCD). American Society of Hematology Annual meeting 2025, Orlando Florida(Abs25-11573), December 2025 Notes: Poster presentation.
Weronika Ortmann, Anna Prykhodko, Hyunjun Kim, Abigail Skidmore, Steven Jiang, Lubica Rauova, Mortimer Poncz, Kandace Gollomp : Hepatic intravital imaging reveals the contribution of peptidylarginine deiminase 4 (PAD4) to the spatiotemporal dynamics of neutrophil recruitment and NET release during bacterial infection. American Society of Hematology Annual Meeting 2025(Abs25-13954), December 2025 Notes: Poster presentation
Molly Brakhane, Vittorio Abbonante, Angelo Laranjeira, Christian Di Buduo, Brooke Sadler, Katrina Ashworth, Tim Kong, Christopher Letson, Fan He, Mary Fulbright, Joshua Siner, Dong Chen, Regina Clemens, Elena Pegoraro, Michele Lambert, Kandace Gollomp, Jorge Di Paola, Alessandra Balduini, Stephen Oh : Activating STIM1 mutations drive the development of myelofibrosis. American Society of Hematology Annual Meeting 2025, Orlando Florida(Abs25-4556), December 2025.
Anh Ngo, Weronika Ortmann, Abigail Skidmore, Hyunjun Kim, Jenna Oberg, Amrita Sarkar, Veronica Bochenek, Nate Levine, Lubica Rauova, Irina Chernysh, Zachary Martinez, Caroline Diorio, Mark Goulian, Victor Nizet, Mortimer Poncz, Kandace Gollomp: Platelet factor 4 (PF4) modulates endothelial cell antimicrobial activity to enhance bacterial clearance and improve sepsis outcomes. American Society of Hematology Annual Meeting 2025, Orlando Florida (Abs25-12393), December 2025.
Hilary Whitworth, Hem Regmi, Anna Prykhodko, Leslie Raffini, Mortimer Poncz, E. Vincent Faustino, Kandace Gollomp: Cell-free DNA is associated with central venous catheter-associated deep venous thrombosis in critically ill children. ASH Annual Meeting, 2025 Orlando Florida (Abs25-10363), December 2025 Notes: Oral presentation
Anh T P Ngo, Weronika Ortmann, Abigail Skidmore, Hyunjun Kim, Jenna Oberg, Amrita Sarkar, Veronica Bochenek, Nate Levine, Lubica Rauova, Irina Chernysh , Zachary Martinez, Caroline Diorio, Mark Goulian, Victor Nizet, Mortimer Poncz, Kandace Gollomp: Platelet factor 4 modulates endothelial cell antimicrobial activity to enhance bacterial clearance and improve sepsis outcomes. bioRxiv [Preprint] September 2025.
Santosh Kumar Yadav, Abigail Skidmore, Weronika Ortmann, Jayachandran N. Kizhakkedathu, Manuela Roggiani, Mark Goulian, Amrita Sarkar, Lubica Rauova, Douglas Cines, Mortimer Poncz, Kandace Gollomp: Macromolecular polyanion inhibitors (MPIs) compact neutrophil extracellular traps (NETs) to enhance bacterial capture and killing Annual Meeting of the International Society of Thrombosis and Hemostasis June 2025 Notes: Poster Presentation
Abigail Skidmore 1, Santosh Kumar Yadav 1, Weronika Ortmann 1, Anh T Ngo, Amrita Sarkar, Gowthami Arepally, Lubica Rauova, Mortimer Poncz, Kandace Gollomp : An IgG4 heparin-induced thrombocytopenia (HIT)-like antibody modifies neutrophil extracellular traps (NETs) to enhance bacterial capture and killing Annual Meeting of the International Society of Hemostasis and Thrombosis June 2025 Notes: Oral presentation.
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