Faculty

Jina Ko, PhD

Assistant Professor of Pathology and Laboratory Medicine

Department: Pathology and Laboratory Medicine

Graduate Group Affiliations

Contact information

422 Curie Blvd
Philadelphia, PA 19104-4283

Email:
Jina.Ko@Pennmedicine.upenn.edu

Education:
B.S.
Rice University, 2013.
Ph.D.
University of Pennsylvania, 2018.

Links
This is my postdoctoral fellowship website that introduces my research with some videos.
Lab website

Permanent link

> Perelman School of Medicine > Faculty > Details

Description of Research Expertise

Medical Diagnostics, Droplet Microfludiics, Biomarker Discovery, Microfabrication

Selected Publications

U. Chintapula, S. Liu, A. Fernandez Del Castillo, J. Lim, Y. Roh, X. Zhang, RT. Morales, M. Sellmyer, X. Xu, J. Ko: Droplet Squeeze Microfluidic Platform for Generating Extracellular Vesicle Hybrids for Drug Delivery. Small 2025.

D.E. Reynolds*, Y. Roh*, U. Chintapula, E. Huynh, P. Vallapureddy, H. H. Tran, D. Lee, M. G. Allen, X. Xu, J. Ko.: Vertically Aligned Nanowires for Longitudinal Intracellular Sampling. ACS Nano 2025.

J. Lim, D. Oh, M. Cheng, U. Chintapula, S. Liu, D. E. Reynolds, X. Zhang, X. Xu, J. Ko. : Enhancing Chimeric Antigen Receptor T-Cell Generation via Microfluidic Mechanoporation and Lipid Nanoparticles. Small 2025.

D.E. Reynolds, Y. Roh, D. Oh, P. Vallapureddy, J. Ko.: Temporal and Spatial Omic Technologies for 4D Profiling. Nature Methods 2025.

Y. Roh*, RT. Morales*, E. Huynh, U. Chintapula, D.E. Reynolds, R.J. Agosto Nieves, D. Oh, A.J. Seiner, J. Lim, C. B. Rodell, J. Ko: Squeezable Hydrogel Microparticles for Single Extracellular Vesicle Protein Profiling. Small OCT 2024 Notes: Online Version of Record before inclusion in an issue 2407809.

D. Koo, X. Cheng, S. Udani, D. Zhu, J. Li, B. Hall, N. Tsubamoto, J. Ko, K. Cheng, D. Di Carlo: Optimizing cell therapy by sorting cells with high extracellular vesicle secretion. Nature Communications 15: 4870, JUNE 2024 Notes: Alt Title: Increasing Cell Therapeutic Potential by Selecting Cells with High Extracellular Vesicle Secretion.

Z. Tang, D.E. Reynolds, C. Lv, D. Zhang, J. Ko, Y. Wang: A Versatile Microchannel Array Device for Portable and Parallel Droplet Generation. Small Science 4(5), MAR 2024 Notes: no publication month.

U. Chintapula, D. Oh, C. Perez, S. Davis, J. Ko: Anti-cancer bioactivity of sweet basil leaf derived extracellular vesicles on pancreatic cancer cells. Journal of Extracellular Biology 3(2): e142, FEB 2024.

D.E. Reynolds, Y. Sun, X. Wang, P. Vallapureddy, J. Lim, M. Pan, A. Fernadez Del Castillo, J. C. T. Carlson, M. A. Sellmyer, M. Nasrallah, Z. Binder, D. M. O’Rourke, G. Ming, H. Song, J. Ko: Live Organoid Cyclic Imaging. Advanced Science 11(14): 2309289, FEB 2024.

D.E. Reynolds, J. Lim, Y. Roh, U. Chintapula, RT. Morales, D. Oh, J. Ko.: Droplet and Digital Microfluidics: Ideation to Implementation. Elsevier 2024.