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Douglas H. Smith, MD

Robert A. Groff Professor of Teaching and Research in Neurosurgery
Member , Mental Retardation Research Center, University of Pennsylvania
Member , Institute of Medicine and Engineering, University of Pennsylvania
Member , Functional Imaging Center, University of Pennsylvania
Director , Center for Brain Injury and Repair, University of Pennsylvania
Vice Chairman, Teaching and Research, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania
Department: Neurosurgery

Contact information
105 Hayden Hall
3320 Smith Walk
Philadelphia, PA 19104-6316
Office: 215-573-3156
Fax: 215-573-3808
B.S. (Biology)
University of Connecticut, 1981.
M.D. (Medicine)
University of Noreste, 1986.
Post-Graduate Training
Postdoctoral Fellow in Molecular Biology and Protein Chemistry, University of Connecticut Health Center, 1986-1988.
Postdoctoral Fellow in Neuropharmacology and Trauma, University of Connecticut Health Center, 1989-1990.
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Description of Research Expertise

Douglas H. Smith, M.D. is the Robert A. Groff Endowed Professor and Vice Chairman of Neurosurgery at the University of Pennsylvania. He also Directs Penn’s Center for Brain Injury and Repair, which includes over 30 faculty members and their research teams. In addition, Dr. Smith currently serves as the Scientific Director of the Big 10/ Ivy league Consortium on Concussion and he also serves as a member on the Scientific Advisory Boards of the US National Football League (NFL), the National Collegiate Athletic Association (NCAA)-DoD Grand Alliance, “Concussion Assessment, Research and Education” (CARE) Consortium and the International Concussion Society.

For his research efforts, Dr. Smith is Principal Investigator of several multi-center research programs on concussion and TBI-induced neurodegeneration. Dr. Smith also directs an NIH post-doctoral fellow training grant for brain injury. His group has established that damage to brain networks and specifically, diffuse axonal injury (DAI), represents key pathological process underlying concussion symptoms and that the extent of acute axonal pathology is predictive of cognitive outcome. In addition, his group has discovered mechanisms of concussion and more severe TBI that lead to progressive neurodegeneration, including chronic traumatic encephalopathy. These collective efforts are represented in over 250 published scientific reports with an h-index of over 80.
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Last updated: 08/21/2020
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