Stefano B Rivella, PhD

faculty photo
Professor of Pediatrics (Hematology)
Department: Pediatrics
Graduate Group Affiliations

Contact information
Children’s Hospital of Philadelphia
3615 Civic Center Blvd.
Abramson Research Center, Room 316B
Philadelphia, PA 19104

Philadelphia, PA 19104
Office: 215-590-6840
Fax: 267-426-5476
University of Pavia, 1990.
University of Pavia, 1999.
Permanent link
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Selected Publications

Breda L, Papp TE, Triebwasser MP, Yadegari A, Fedorky MT, Tanaka N, Abdulmalik O, Pavani G, Wang Y, Grupp SA, Chou ST, Ni H, Mui BL, Tam YK, Weissman D, Rivella S, Parhiz H.: In vivo hematopoietic stem cell modification by mRNA delivery. Science 381: 436-443, Jul 2023.

Guerra A, Parhiz H, Rivella S.: Novel potential therapeutics to modify iron metabolism and red cell synthesis in diseases associated with defective erythropoiesis. Haematologica Jun 2023.

Bou-Fakhredin R, Rivella S, Cappellini MD, Taher AT.: Pathogenic Mechanisms in Thalassemia I: Ineffective Erythropoiesis and Hypercoagulability. Hematol Oncol Clin North Am 2023.

Noguchi K, Ikawa Y, Takenaka M, Sakai Y, Fujiki T, Kuroda R, Chappell M, Ghiaccio V, Rivella S, Wada T.: Protocol for a high titer of BaEV-Rless pseudotyped lentiviral vector: Focus on syncytium formation and detachment. J Virol Methods 2023.

Ganz T, Nemeth E, Rivella S, Goldberg P, Dibble AR, McCaleb ML, Guo S, Monia BP, Barrett TD.: TMPRSS6 as a Therapeutic Target for Disorders of Erythropoiesis and Iron Homeostasis. Adv Ther 2023.

Costa E, Cappellini MD, Rivella S, Chilin A, Alessi E, Riccaboni M, Leufkens HGM, Luzzatto L.: Emergent treatments for β-thalassemia and orphan drug legislations. Drug Discov Today 27: 103342, Sep 2022.

Di Modica SM, Tanzi E, Olivari V, Lidonnici MR, Pettinato M, Pagani A, Tiboni F, Furiosi V, Silvestri L, Ferrari G, Rivella S, Nai A.: Transferrin receptor 2 (Tfr2) genetic deletion makes transfusion-independent a murine model of transfusion-dependent β-thalassemia. Am J Hematol 2022.

Casu C, Liu A, De Rosa G, Low A, Suzuki A, Sinha S, Ginzburg YZ, Abrams C, Aghajan M, Guo S, Rivella S.: Tmprss6-ASO as a tool for the treatment of Polycythemia Vera mice. PLoS One 16: e0251995, Dec 2021.

Pires Lourenco S, Jarocha D, Ghiaccio V, Guerra A, Abdulmalik O, La P, Zezulin A, Smith-Whitley K, Kwiatkowski JL, Guzikowski V, Nakamura Y, Raabe T, Breda L, Rivella S.: Inclusion of a short hairpin RNA targeting BCL11A into a β-globin expressing vector allows concurrent synthesis of curative adult and fetal hemoglobin. Haematologica 106: 2740-2745, Oct 2021.

Lam LKM, Murphy S, Kokkinaki D, Venosa A, Sherrill-Mix S, Casu C, Rivella S, Weiner A, Park J, Shin S, Vaughan AE, Hahn BH, Odom John AR, Meyer NJ, Hunter CA, Worthen GS, Mangalmurti NS.: DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia. Sci Transl Med 13: eabj1008, Oct 2021.

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Last updated: 09/07/2023
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