Daniel P Kelly, MD

faculty photo
Willard and Rhoda Ware Professor of Diabetes and Metabolic Diseases
Department: Medicine
Graduate Group Affiliations

Contact information
3400 Civic Center Blvd.
Smilow Center for Translational Research
Philadelphia, PA 19104
Office: 215-898-0768
Lab: 215-898-2374
B.S. (Biology)
University of Illinois, 1978.
M.D. (Medicine )
University of Illinois College of Medicine, Chicago, Illinois, 1982.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Zamani P, Proto EA, Wilson N, Fazelinia H, Ding H, Spruce LA, D’Avila Jr A, Mazurek J, Prenner SB, Desjardins B, Margulies KB, Kelly DP, Arany Z, Doulias P-T, Elrod J, Allen ME, McCormack SE, Schur GM, D’Aquilla K, Kumar D, Thakuri D, Prabhakaran K, Langham MC, Poole DC, Seeholzer SH, Reddy R, Ischiropoulos H, Chirinos JA: Multimodality assessment of HFpEF skeletal muscle reveals differences in the machinery of energy fuel metabolism. ESC Heart Failure Aug 2021.

Dierickx P, Jiang C, Xiao Y, Carpenter B, Zhai J, Vermunt MW, Nguyen H, Blobel G, Kelly DP, Pei L, Lazar MA: The circadian REV-ERB nuclear receptors are essential drivers of heart metabolism and function. Nature Cardiovascular Research In press 2021.

Muoio DM, Recchia FA, and Kelly DP: Comments on Crosstalk 49: Ketone bodies serve as an important fuel for the normal and diseased heart. J of Physiol 2021.

Tomoya Sakamoto, Daniel Kelly: A Case for Adaptive Cardiac Hypertrophic Remodeling is CITED. Circulation Research August 2020.

Davidson MT, Grimsrud PA, Lai L, Draper JA, Fisher-Wellman KH, Narowski TM, Koves TR, Kelly DP, Muoio DM: Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure. Circulation Research Jul 2020.

Tomoya Sakamoto , Timothy R Matsuura , Shibiao Wan , David M Ryba , Junil Kim , Kyoung-Jae Won , Ling Lai , Christopher Petucci , Nataliya Petrenko , Kiran Musunuru , Rick B Vega , and Daniel P Kelly: A Critical Role for Estrogen-related Receptor Signaling in Cardiac Maturation. Circulation Research Jun 2020.

Selvaraj S, Kelly DP, Margulies KB: Implications of Altered Ketone Metabolism and Therapeutic Ketosis in Heart Failure. Circulation Jun 2020.

Zamani P, Proto EA, Mazurek J, Prenner S, Margulies KB, Townsend RR, Kelly DP, Arany ZP, Poole DC, Wagner PD, Chirinos JA: Peripheral Determinants of Oxygen Utilization in Heart Failure with Preserved Ejection Fraction: Central Role of Adiposity. JACC: Basic to Transnational Science March 2020.

Timothy R. Matsuura, Teresa C. Leone, Daniel P. Kelly: Fueling Cardiac Hypertrophy. Circulation Research 126(2): 197 - 199, Jan 2020.

Yurista SR, Matsuura TR, Silljé HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, Oberdorf-Maass SU, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD: Ketone ester treatment improves cardiac function and reduces pathologic remodeling in pre-clinical models of heart failure. Circ Heart Failure In press 2020.

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Last updated: 09/13/2021
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