Arndt Siekmann, Ph.D.

faculty photo
Associate Professor of Cell and Developmental Biology
Department: Cell and Developmental Biology
Graduate Group Affiliations

Contact information
1114 Biomedical Research Building II/III
421 Curie Boulevard
Philadelphia, PA 19104
Office: 215-898-7805
BS (Biology)
Albert-Ludwigs-Universität Freiburg, 2000.
PhD (Molecular Cell Biology and Genetics)
Max Planck Institute, 2004.
Permanent link
> Perelman School of Medicine   > Faculty   > Details

Selected Publications

Elvin V. Leonard, Sana S. Hasan, Arndt F. Siekmann: Temporally and regionally distinct morphogenetic processes govern zebrafish caudal fin blood vessel network expansion. Development April 2023.

Leonard EV, Figueroa RJ, Bussmann J, Lawson ND, Amigo JD, Siekmann AF.: Regenerating vascular mural cells in zebrafish fin blood vessels are not derived from pre-existing mural cells and differentially require Pdgfrb signalling for their development. Development 149: dev199640, Apr 2022.

Lange M, Ohnesorge N, Hoffmann D, Rocha SF, Benedito R, Siekmann AF.: Zebrafish mutants in vegfab can affect endothelial cell proliferation without altering ERK phosphorylation and are phenocopied by loss of PI3K signaling. Dev Biol 486: 26-43, Mar 2022.

Tsaryk R, Yucel N, Leonard EV, Diaz N, Bondareva O, Odenthal-Schnittler M, Arany Z, Vaquerizas JM, Schnittler H, Siekmann AF.: Shear stress switches the association of endothelial enhancers from ETV/ETS to KLF transcription factor binding sites. Sci Rep 12: 4795, Mar 2022.

Benman W., Berlew E.E., Deng H., Parker C., Kuznetsov I.A., Lim B., Siekmann A.F., Chow B.Y., Bugaj L.J.: Temperature-responsive optogenetic probes of cell signaling. Nature Chemical Biology December 2021.

Gao P, Chen C, Howell ED, Li Y, Tober J, Uzun Y, He B, Gao L, Zhu Q, Siekmann AF, Speck NA, Tan K: Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells. Genes and Development 34: 950, June 2020.

Santoro MM, Beltrame M, Panáková D, Siekmann AF, Tiso N, Venero Galanternik M, Jung HM, Weinstein BM: Advantages and Challenges of Cardiovascular and Lymphatic Studies in Zebrafish Research. Frontiers in Cell and Developmental Biology(7), 89, May 2019.

Red-Horse Kristy, Siekmann Arndt F: Veins and Arteries Build Hierarchical Branching Patterns Differently: Bottom-Up versus Top-Down. BioEssays : news and reviews in molecular, cellular and developmental biology 41(3): e1800198, Mar 2019.

Bondareva Olga, Tsaryk Roman, Bojovic Vesna, Odenthal-Schnittler Maria, Siekmann Arndt F, Schnittler Hans-J: Identification of atheroprone shear stress responsive regulatory elements in endothelial cells. Cardiovascular research Feb 2019.

Benedito, Rui and Siekmann, Arndt Friedrich: The European Society of Cardiology (ESC) textbook of Cardiovascular Biology. Blood vessel differentiation and growth. Perez-Pomares, Jose and Kelly, Robert (eds.). Oxford University Press, ISBN: 9780198757269, October 2018.

back to top
Last updated: 05/16/2023
The Trustees of the University of Pennsylvania