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Paul A. Offit
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Maurice R. Hilleman Chair of Vaccinology
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Department: Pediatrics
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Graduate Group Affiliations
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Contact information
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Division of Infectious Diseases
2e Abramson Research Building, Room 1202D
3a 3615 Civic Center Blvd.
Philadelphia, PA 19104
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2e Abramson Research Building, Room 1202D
3a 3615 Civic Center Blvd.
Philadelphia, PA 19104
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Office: (215) 590-2020
35 Fax: (215) 590-2025
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35 Fax: (215) 590-2025
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Email:
OFFIT@EMAIL.CHOP.EDU
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OFFIT@EMAIL.CHOP.EDU
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Publications
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Education:
21 9 B.S. c
2a Tufts University , 1973.
21 9 M.D. c
2f University of Maryland, 1977.
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21 9 B.S. c
2a Tufts University , 1973.
21 9 M.D. c
2f University of Maryland, 1977.
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Links
b0 Search PubMed for articles
bb Website for Vaccine Education Center designed to provide up-to-date, scientifically accurate information about vaccines.
41 Immunology graduate group faculty webpage.
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3
3
90
Permanent linkb0 Search PubMed for articles
bb Website for Vaccine Education Center designed to provide up-to-date, scientifically accurate information about vaccines.
41 Immunology graduate group faculty webpage.
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5e
54 rotavirus, rotavirus vaccine, intestinal immunity, vaccines, vaccine safety
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4c Key words: rotavirus, rotavirus vaccine, intestinal immunity.
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26 Description of Research
141 We studied the genetics of rotavirus virulence, rotavirus neutralization phenotype and protein-specificities of rotavirus-specific cytotoxic T lymphocytes as a prelude to making a bovine-human reassortant rotavirus vaccine. The vaccine, RotaTeq, was licensed by the Food and Drug Administration in February, 2006.
8
20 Rotation Projects
14a None. The laboratory closed in December, 2005. My professional time is devoted to running the Vaccine Education Center at the Children’s Hospital of Philadelphia: an international center that creates educational materials for parents and healthcare professionals and runs on an endowment yielding about $500,000 per year.
26 29
27
Description of Research Expertise
2b Research Interests54 rotavirus, rotavirus vaccine, intestinal immunity, vaccines, vaccine safety
8
4c Key words: rotavirus, rotavirus vaccine, intestinal immunity.
8
26 Description of Research
141 We studied the genetics of rotavirus virulence, rotavirus neutralization phenotype and protein-specificities of rotavirus-specific cytotoxic T lymphocytes as a prelude to making a bovine-human reassortant rotavirus vaccine. The vaccine, RotaTeq, was licensed by the Food and Drug Administration in February, 2006.
8
20 Rotation Projects
14a None. The laboratory closed in December, 2005. My professional time is devoted to running the Vaccine Education Center at the Children’s Hospital of Philadelphia: an international center that creates educational materials for parents and healthcare professionals and runs on an endowment yielding about $500,000 per year.
26 29
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131 Chow, A.A., Moser C.A., Speaker, T.J., and Offit, P.A. : Determination of efficiency of attachment of biotinylated antibodies to avidin-linked, aqueous-based microcapsules by flow cytometry. J. Immunol. Methods 277: 135-139, 2003.
ec Offit, P.A., Jew, R.K.: Addressing parents’ concerns: Do vaccines contain harmful preservatives, adjuvants, additives, or residuals? Pediatrics [in press] 2003.
be Offit, P.A. and Coffin, S.E. : Communicating science to the public: MMR vaccine and autism. Vaccine [in press] 2003.
129 Offit, PA, HF Clark, and RL Ward. : Current state of development of human rotavirus vaccines. Viral Gastroenteritis. U. Desselberger and J. Gray (eds.). Elsevier Science BV, Amsterdam, The Netherlands, Page: 345-356, 2003.
133 Ward RL, HF Clark, PA Offit, and RI Glass.: Live vaccine strategies to prevent rotavirus disease. New Generation Vaccines. M.M. Levine, G.C. Woodrow, J.B. Kaper, and G.S. Cobon (eds.). Marcel Dekker, Inc., New York, NY, in press 2003.
eb Clark, H F., P.A. Offit, R.I. Glass, and RM Ward. : Rotavirus vaccines. Vaccines, 4th Edition. S.A.Plotkin and W. Orenstein (eds.). W.B. Saunders in press 2003.
114 Offit P.A., and C.J. Hackett. : Do vaccines weaken, overwhelm, or alter the normal balance of the immune system. Vaccines, 4th Edition. S.A.Plotkin and W. Orenstein (eds.). W.B. Saunders in press 2003.
a1 Offit, PA. : Getting "fully informed" about vaccines. Contemp. Pediatr. in press 2003.
8f Offit, P.A.: The power of 'box a'. Expert Rev Vaccines 2: 1-3, 2003.
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Selected Publications
dc Offit, P.A. and Hackett, C.J. : Addressing parents’ concerns: Do vaccines cause allergic or autoimmune diseases? Pediatrics 111: 653-659, 2003.131 Chow, A.A., Moser C.A., Speaker, T.J., and Offit, P.A. : Determination of efficiency of attachment of biotinylated antibodies to avidin-linked, aqueous-based microcapsules by flow cytometry. J. Immunol. Methods 277: 135-139, 2003.
ec Offit, P.A., Jew, R.K.: Addressing parents’ concerns: Do vaccines contain harmful preservatives, adjuvants, additives, or residuals? Pediatrics [in press] 2003.
be Offit, P.A. and Coffin, S.E. : Communicating science to the public: MMR vaccine and autism. Vaccine [in press] 2003.
129 Offit, PA, HF Clark, and RL Ward. : Current state of development of human rotavirus vaccines. Viral Gastroenteritis. U. Desselberger and J. Gray (eds.). Elsevier Science BV, Amsterdam, The Netherlands, Page: 345-356, 2003.
133 Ward RL, HF Clark, PA Offit, and RI Glass.: Live vaccine strategies to prevent rotavirus disease. New Generation Vaccines. M.M. Levine, G.C. Woodrow, J.B. Kaper, and G.S. Cobon (eds.). Marcel Dekker, Inc., New York, NY, in press 2003.
eb Clark, H F., P.A. Offit, R.I. Glass, and RM Ward. : Rotavirus vaccines. Vaccines, 4th Edition. S.A.Plotkin and W. Orenstein (eds.). W.B. Saunders in press 2003.
114 Offit P.A., and C.J. Hackett. : Do vaccines weaken, overwhelm, or alter the normal balance of the immune system. Vaccines, 4th Edition. S.A.Plotkin and W. Orenstein (eds.). W.B. Saunders in press 2003.
a1 Offit, PA. : Getting "fully informed" about vaccines. Contemp. Pediatr. in press 2003.
8f Offit, P.A.: The power of 'box a'. Expert Rev Vaccines 2: 1-3, 2003.
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