Faculty

Lucie Guo

Assistant Professor of Ophthalmology

Department: Ophthalmology

Graduate Group Affiliations

Cell and Molecular Biology

Contact information

422 Curie Blvd, Stellar Chance M8B
Philadelphia, PA 19104

Email:
lucie.guo@pennmedicine.upenn.edu

Education
BA (Biochemical Sciences)
Harvard University, 2010.
PhD (Biochemistry and Molecular Biophysics)
University of Pennsylvania, 2018.
MD (Medicine)
University of Pennsylvania, 2018.

Links
lab website

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Lucie Y Guo, Daniel SW Ting: From black boxes to biomarkers: artificial intelligence in surgical retina. Ophthalmology Retina (in press) June 2026.

Melissa Yuan, Amer Alsoudi, Purna Nangia, Lucie Guo, Ahmad Al-Moujahed, Chase A Ludwig, Karen M Wai, Prithvi Mruthyunjaya, Ehsan Rahimy: Prevalence and incidence of mental health disorders in patients with inherited retinal diseases: a population-based study. J AAPOS May 2026.

Anas Alkhabaz, Joseph Waiguru, Lucie Y Guo, Jared Sokol, Carolyn Pan, Charles DeBoer: Regression of a Subretinal Proliferation Band with Intravitreal Methotrexate in Recurrent Retinal Detachment. Retinal Cases and Brief Reports April 2026.

Anas Alkhabaz, Lucie Y Guo, Charles DeBoer: Foreign Body Presenting as Golden Hypopyon. Surgeries September 2025.

Thakur S, Guo LY, Mruthyunjaya P.: An Unusual Pigmented Lesion. Ophthalmology 132(1): e14, Jan 2025.

Soetikno BT, Ghoraba H, Brant A, DeBoer C, Guo L, Shue A, Hartnett ME.: Retinal racemose hemangioma presenting with a chorioretinal anastomosis. Am J Ophthalmol Case Rep 36(16): 102188, Oct 2024.

Guo LY, Mishra K, Leung LB.: Severe progression of pentosan maculopathy over a decade. Am J Ophthalmol Case Rep 30(8): 101826, Mar 2023.

Kempton HR, Love KS, Guo LY, Qi LS.: Scalable biological signal recording in mammalian cells using Cas12a base editors. Nat Chem Biol 18(7): 742-750, July 2022.

Guo LY, Bian J, Davis AE, Liu P, Kempton HR, Zhang X, Chemparathy A, Gu B, Lin X, Rane DA, Xu X, Jamiolkowski RM, Hu Y, Wang S, Qi LS.: Multiplexed genome regulation in vivo with hyper-efficient Cas12a. Nat Cell Biol 24(4): 590-600, April 2022.

Guo LY, Jamiolkowski RM, Hassan M, Leng T.: A buoyant mass in the brain: Intraventricular migration of silicone oil. Am J Ophthalmol Case Rep 25(3): 101399, Feb 2022.