Faculty

Benjamin Jacob Samelson-Jones, MD, PhD

faculty photo
Assistant Professor of Pediatrics at the Children's Hospital of Philadelphia
Department: Pediatrics
Graduate Group Affiliations

Contact information
The Children's Hospital of Philadelphia
Colket Translational Research Building, Rm 5016
3501 Civic Center Blvd
Philadelphia, PA 19104
Office: 267-425-0147
Fax: 215-590-3660
Education:
AB (Physics )
Amherst College, 2001.
MS
Albert Einstein College of Medicine, 2006.
MD
Albert Einstein College of Medicine, 2009.
PhD (Biophysics)
Albert Einstein College of Medicine, 2009.
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Selected Publications

Arruda VR, Doshi BS, Samelson-Jones B: Emerging therapies for hemophilia: controversies and unanswered questions. F1000 Research Page: In press, 2018.

French RA, Samelson-Jones B, Niemeyer GP, Lothrop CD, Merricks EP, Nichols TC, Arruda VR: Complete correction of hemophilia B phenotype by FIX-Padua skeletal muscle gene therapy in an inhibitor-prone dog model. Blood Advances Page: In press, 2018.

Samelson-Jones BJ, Kramer PM, Chicka M, Gunning III WT, Lambert MP: MYH9-macrothrombocytopenia caused by a novel variant (E1421K) initially presenting as apparent neonatal alloimmune thrombocytopenia. Pediatric Blood and Cancer 65(4): doi: 10.1002, 2018.

George LA, Ragni MV, Samelson-Jones B, Cuker A, Runoski AR, Cole G, Wright F, Chen Y, Hui DJ, Wachtel K, Takefman D, Couto LB, Reape KZ, Carr ME, Anguela XM, High KA: Spk-8011: Preliminary Results from a Phase 1/2 Dose Escalation Trial of an Investigational AAV-Mediated Gene Therapy for Hemophilia a. Blood 130(1): 604, Dec 2017.

Parsons NA, Ho MD, Davidson RJ, Thalji NK, Samelson-Jones B, Camire RM, George LA: Regulation of Factor VIII By Activated Protein C: Assessment In Vitro and In Vivo. Blood 130(1): 3650, Dec 2017.

George LA, Sullivan SK, Giermasz A, Samelson-Jones B, Ducore JM, Teitel JM, Cuker A, Von Mackensen S, Majumdar S, McGuinn CE, Runoski AR, Wright F, Dasen S, Barber K, Chen Y, Hui DJ, Patel R, Liu Y, Wachtel K, Takefman D, Couto LB, Reape KZ, Carr CE, Anguela XM, High KA : Spk-9001: Adeno-Associated Virus Mediated Gene Transfer for Hemophilia B – 1 Year Follow up and Impact of Baseline Characteristics on Transgene-Derived Factor IX Activity and Persistence. Blood 130(1): 601, Dec 2017.

Hui DJ, Liu Y, Patel R, Chen Y, George LA, Sullivan SK, Giermasz A, Rasko J, Samelson-Jones B, Ducore JM, Dasen S, Carr ME, Anguela XM, High KA: Spk-9001: Adeno-Associated Virus Mediated Gene Transfer for Hemophilia B Achieves Sustained Factor IX with Minimal Immune Response. Blood 130(1): 2056, Dec 2017.

Samelson-Jones B, French RA, Crudele JM, Nichols TC, Arruda VR: The Role of Transgene Levels in Immune Tolerance Induction after AAV Gene Therapy in Hemophilia B Canine Models. Blood 130(1): 2057, Dec 2017.

Arruda VR, Doshi BS, Samelson-Jones B.: Novel approaches to hemophilia therapy: successes and challenges. Blood 130(21): 2251-2256, Novemeber 2017.

George, L.A., Sullivan, S.K., Giermasz, A, Ducore, J. M, Teitel, J.M., Samelson-Jones, B., Cuker, A, Sullivan, L.M., Majumdar, S., McGuinn, C.E., Galvao, A.M., Luk A.Y., Wright, J.F., Chen, Y., Hui, D.J., Wachtel, K., Galas, T., Takefman, D., Couto, L.B., Carr, M.E., Anguela, X.M., High, K.A. : Initiation of Oral Steroid Therapy Produced Rapid Normalization of Transaminase Levels and Stabilization of FIX Activity in Subjects Who Developed Capsid Directed T-Cell Responses in the SPK-9001: Adeno-Associated Virus Mediated Gene Transfer for Hemophilia B Phase 1/2 Trial. Hemostasis and Thrombosis Research Society Annual Meeting, Scottsdale, AZ Apr 2017 Notes: poster.

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Last updated: 03/22/2018
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